Characterization of pathological alterations in the central nervous system of red foxes caused by canine distemper virus

2020 ◽  
Author(s):  
F. Geiselhardt ◽  
M. Peters ◽  
S. Kleinschmidt ◽  
M. Ludlow ◽  
A. Beineke
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Red Foxes ◽  
The Central Nervous System

scholarly journals The nervous form of canine distemper

2018 ◽  
Vol 13 (2) ◽  
pp. 125-136
Author(s):  
Alice Fernandes Alfieri ◽  
Alexandre Mendes Amude ◽  
Amauri Alcindo Alfier
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Demyelinating Disease ◽  
Clinical Course ◽  
Systemic Infection ◽  
Canine Distemper ◽  
Systemic Involvement ◽  
Clinical Syndromes ◽  
The Central Nervous System

Canine distemper is a systemic infection, frequently lethal in dogs. The canine distemper virus(CDV) causes a persistent infection within the central nervous system resulting in aprogressive, multifocal demyelinating disease. In dogs, CDV infection may lead togastrointestinal and/or respiratory signs, frequently with central nervous system involvement.Myoclonus has been a common and characteristic sign observed in dogs with distemperencephalomyelitis. However, the nervous form of distemper may occur in the absence ofmyoclonus and systemic involvement. This review will point the clinical course and theneurological signs of nervous distemper, as well the clinical syndromes of CDV infection,neuropathology of acute and chronic demyelination, and diagnostic aids of CDVencephalomyelitis.

Studies on canine distemper virus persistence in the central nervous system

1995 ◽  
Vol 89 (5) ◽  
pp. 438-445 ◽  
Author(s):  
Cornelia F. M�ller ◽  
Rosmarie S. Fatzer ◽  
Karin Beck ◽  
Marc Vandevelde ◽  
Andreas Zurbriggen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Virus Persistence ◽  
The Central Nervous System

scholarly journals Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Watanyoo Pratakpiriya ◽  
Angeline Ping Ping Teh ◽  
Araya Radtanakatikanon ◽  
Nopadon Pirarat ◽  
Nguyen Thi Lan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Virus Receptor ◽  
The Central Nervous System

scholarly journals Early T cell response in the central nervous system in canine distemper virus infection

1999 ◽  
Vol 97 (1) ◽  
pp. 45-56 ◽  
Author(s):  
A. Tipold ◽  
P. Moore ◽  
A. Zurbriggen ◽  
I. Burgener ◽  
G. Barben ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
T Cell ◽  
Virus Infection ◽  
Cell Response ◽  
Canine Distemper Virus ◽  
T Cell Response ◽  
Canine Distemper ◽  
The Central Nervous System

Studies on canine distemper virus persistence in the central nervous system

1995 ◽  
Vol 89 (5) ◽  
pp. 438-445 ◽  
Author(s):  
Cornelia F. M�ller ◽  
Rosmarie S. Fatzer ◽  
Karin Beck ◽  
Marc Vandevelde ◽  
A. Zurbriggen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Virus Persistence ◽  
The Central Nervous System

scholarly journals Molecular cloning and analysis of l(1)ogre, a locus of Drosophila melanogaster with prominent effects on the postembryonic development of the central nervous system.

Genetics ◽  
1990 ◽  
Vol 126 (4) ◽  
pp. 1033-1044 ◽  
Author(s):  
T Watanabe ◽  
D R Kankel
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Postembryonic Development ◽  
P Element ◽  
Reading Frame ◽  
Isolation And Characterization ◽  
The Central Nervous System ◽  
Highly Hydrophobic ◽  
Conceptual Translation

Abstract Previous genetic studies have shown that wild-type function of the l(1)ogre (lethal (1) optic ganglion reduced) locus is essential for the generation and/or maintenance of the postembryonic neuroblasts including those from which the optic lobe is descended. In the present study molecular isolation and characterization of the l(1)ogre locus was carried out to study the structure and expression of this gene in order to gain information about the nature of l(1)ogre function and its relevance to the development of the central nervous system. About 70 kilobases (kb) of genomic DNA were isolated that spanned the region where l(1)ogre was known to reside. Southern analysis of a l(1)ogre mutation and subsequent P element-mediated DNA transformation mapped the l(1)ogre+ function within a genomic fragment of 12.5 kb. Northern analyses showed that a 2.9-kb message transcribed from this 12.5-kb region represented l(1)ogre. A 2.15-kb portion of a corresponding cDNA clone was sequenced. An open reading frame (ORF) of 1,086 base paris was found, and a protein sequence of 362 amino acids with one highly hydrophobic segment was deduced from conceptual translation of this ORF.

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