scholarly journals Three Case Reports of Intravenous Leiomyomatosis with Intracardiac Extensions

2020 ◽  
Vol 09 (01) ◽  
pp. e40-e43
Author(s):  
Yundan Deng ◽  
Bing Song
Keyword(s):  
Gold Standard ◽  
Tumor Recurrence ◽  
Benign Tumor ◽  
Case Reports ◽  
Perioperative Complications ◽  
Biological Behavior ◽  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
Intracardiac Extension ◽  
The Right

Abstract Background Intravenous leiomyomatosis is a rare disease. Histologically, intravenous leiomyomatosis is a benign tumor, but its biological behavior can be malignant. The development of intracardiac extensions leads to congestive heart failure and occasionally sudden fatalities. Case Description The cases of three patients treated at our university between 2017 and 2018 were studied retrospectively. Intravenous tumors extending into the right heart system were fully removed without perioperative complications or death. Only one tumor recurrence was observed during the followed-up period. Conclusion The gold standard for the treatment of intravenous leiomyomatosis with intracardiac extension is complete and successful surgical resection.

Orthostatic hypotension and right heart failure as the initial manifestation of intravenous leiomyomatosis

2015 ◽  
Vol 26 (3) ◽  
pp. 586-588 ◽  
Author(s):  
Ya-Qin Li ◽  
Xiao-Ping Yin ◽  
Zhan-Wen Xu
Keyword(s):  
Right Atrium ◽  
Right Heart Failure ◽  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
Caval Vein ◽  
Initial Manifestation ◽  
Inferior Caval Vein ◽  
Mobile Mass ◽  
History Of ◽  
The Right

AbstractA 36-year-old woman, who had a history of myomectomy, presented with lightheadedness after changing position from sitting to standing and effort-related shortness of breath. Echocardiography demonstrated a hyperechoic elongated mobile mass extending from the inferior caval vein to the right atrium. The mass was surgically removed, and histological examination established the diagnosis of intravenous leiomyomatosis. This case caught the attention of our cardiology group to consider the diagnosis when an inferior caval vein or right atrium mass is found in a patient with a history of uterine leiomyomatosis.

scholarly journals Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Haruhisa Konishi ◽  
Iemasa Koh ◽  
Noriyuki Shiroma ◽  
Yukie Kidani ◽  
Satoshi Urabe ◽  
...  
Keyword(s):  
Uterine Leiomyoma ◽  
Case Reports ◽  
Hormonal Treatment ◽  
Benign Neoplasm ◽  
Blue Staining ◽  
Alcian Blue Staining ◽  
Intravenous Leiomyomatosis ◽  
Complete Surgical Resection ◽  
The Right ◽  
Different Levels

Intravenous leiomyomatosis (IVL) is a rare benign neoplasm. Herein, we describe two cases of IVL at different levels of progression. The tumor in Case 1 was extensive, invading the right atrium after a hysterectomy for a uterine myoma. The tumor temporarily responded to hormonal treatment; however, tumor regrowth occurred. In contrast, the tumor in Case 2 extended only to the pelvic veins and was revealed preoperatively. Hysterectomy and bilateral salpingo-oophorectomy were performed, resulting in the complete surgical resection of the tumor. In Case 2, no recurrence has been observed. Tumor samples were evaluated for hyaluronan expression using Alcian blue staining (with and without hyaluronidase digestion). The tumor in Case 1 stained strongly positive for hyaluronan while the tumor in Case 2 stained weakly positive for hyaluronan. In contrast, a large non-IVL uterine leiomyoma (control) stained negative for hyaluronan. These results suggest a relationship between tumor hyaluronan expression and IVL progression, similar to that in other cancers.

scholarly journals Surgical treatment of intravenous leiomyomatosis involving the right heart: a case series

2019 ◽  
Vol 47 (7) ◽  
pp. 3465-3474
Author(s):  
Guangze Luo ◽  
Hongrui Pan ◽  
Jiaxue Bi ◽  
Yudong Luo ◽  
Jiechang Zhu ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Case Series ◽  
Iliac Vein ◽  
Right Atrial ◽  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
The Right

Objective This study was performed to investigate the surgical treatment of intravenous leiomyomatosis involving the right heart. Methods The clinical data of five patients with intracardiac leiomyomatosis treated from April 2002 to October 2017 at a single center were retrospectively analyzed. Results All five patients underwent successful intravenous and right atrial tumor removal via abdominal and inferior vena cava incisions. In three patients, these incisions were combined with thoracotomy and a right atrial incision, and in two patients, they were combined with uterine and bilateral fallopian tube and ovarian resection. One patient with advanced disease underwent a one-stage procedure and died thereafter. Of the remaining four patients who underwent follow-up for 1.5 to 12.0 years, one developed recurrence at 1 year postoperatively. The recurrent tumor, which was pathologically confirmed to be an intravenous leiomyoma, was removed via inferior vena cava and internal iliac vein incisions without subsequent recurrence. Conclusions The main treatment goal for inferior vena cava leiomyomas involving the right heart is to first address the severe obstruction of cardiac blood flow and then pursue second-stage surgery. Concurrent thoracotomy appears unnecessary because moderately sized right heart tumors can be gently removed via the inferior vena cava.

One-Stage Surgical Removal of Intravenous Leiomyomatosis with Right Heart Extension is Safe

2011 ◽  
Vol 14 (3) ◽  
pp. 192 ◽  
Author(s):  
Qiang Li ◽  
Jie Ma ◽  
Bin Hao ◽  
Xintao Pi ◽  
Hao Li
Keyword(s):  
Smooth Muscle ◽  
Circulatory Arrest ◽  
Smooth Muscle Tumor ◽  
Resected Specimen ◽  
Surgical Removal ◽  
Histopathologic Examination ◽  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
Intracardiac Extension ◽  
Muscle Tumor

Intravenous leiomyomatosis is a rare smooth muscle tumor. We report the case of a 42-year-old woman with both intravenous and intracardiac extension of leiomyomatosis who underwent 3 operations within 9 years. During the last admission, she underwent a successful single-stage surgical approach while under cardiopulmonary bypass with circulatory arrest. A postoperative histopathologic examination of the resected specimen confirmed the diagnosis.

scholarly journals A one-stage approach to the treatment of intravenous leiomyomatosis extending to the right heart

2010 ◽  
Vol 52 (1) ◽  
pp. 212-215 ◽  
Author(s):  
Pietro Rispoli ◽  
Davide Santovito ◽  
Caterina Tallia ◽  
Gianfranco Varetto ◽  
Massimo Conforti ◽  
...  
Keyword(s):  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
One Stage ◽  
The Right

scholarly journals Parotid Myoepithelial Carcinoma in a Pediatric Patient with Multiple Recurrences: Case Report

2021 ◽  
pp. 989-997
Author(s):  
Harold Bravo Thompson ◽  
Maria Lim Law ◽  
Ruth Vergara Vasquez ◽  
Omar Castillo Fernandez
Keyword(s):  
De Novo ◽  
Case Reports ◽  
Hepatic Metastases ◽  
Distant Metastases ◽  
Biological Behavior ◽  
Myoepithelial Carcinoma ◽  
Temporal Fossa ◽  
Parotid Region ◽  
The Right ◽  
Multiple Recurrences

Myoepithelial carcinoma of the salivary glands is a rare entity, with scarce amount of case reports in the literature. Due to its infrequency, its diagnosis is usually difficult and uncertain. Although there are reports of locoregional recurrences and distant metastases, its low incidence and varied biological behavior limits the clinical evidence that can be used to predict the prognosis and determine the course of treatment. We present a 23-year-old female patient without past medical history with an initial 1-year history of volume increase in the right parotid region of tumor aspect and painful on palpation. As a malignancy was suspected, a total parotidectomy was performed, reporting in the deep lobe a parotid myoepithelial carcinoma with vascular and neural invasion, negative borders, and 3–9 negative regional nodes. During her 16-year clinical evolution, she presented approximately every 2 years and a total of 9 locoregional recurrences and hepatic metastases, including cervical lymphoid nodules, temporal bone, frontal bone, and temporal fossa. Those recurrences have been treated with coordinated efforts between repeated external radiotherapy, chemotherapy, and multiple surgical resections. Myoepithelial tumors represent only 1.0–1.5% of all salivary gland tumors. The literature reports suggest a high incidence of locoregional recurrences and distant metastases in de novo myoepithelial carcinomas. Due to its rarity, treatment continues to be based on the experience of medical staff.

scholarly journals The importance of cytology in diagnosing rare breast carcinoma: Two case reports

2013 ◽  
Vol 66 (1-2) ◽  
pp. 86-91
Author(s):  
Mirjana Cuk ◽  
Radoslav Gajanin ◽  
Milos Malis ◽  
Drazan Eric ◽  
Nenad Lalovic ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Case Reports ◽  
Outer Region ◽  
Morphological Characteristics ◽  
Final Diagnosis ◽  
Biological Behavior ◽  
Primary Breast Tumor ◽  
Rare Tumors ◽  
The Right

Introduction. This paper presents two cases of very rare tumors of breast: breast sebaceos carcinoma, which has rarely been described in medical literature, and breast carcinosarcoma. Morphological characteristics and biological behavior of sebaceos carcinoma are still rather vague. Carcinosarcoma of the breast is a rare malignancy with distinct cell lines described as a breast carcinoma of ductal type with a sarcoma-like component. Case report. The first presented case is a 73-year-old female referred to our hospital in January 2008 with tumor of the right breast in the upper outer region of the breast and enlarged lymph nodes in the right axillary region. The second presented case is a 51-year-old female with carcinosarcoma, also a very rare primary breast tumor. She was admitted to our hospital in June 2011 with history of lump in the upper and lower outer quadrant of the left breast. In both cases, biopsy of tumor tissue was carried out with a thin needle, i.e. the aspiration cytology was applied as a diagnostic method, and during the operation the fast diagnostics of frozen sections and cytologic diagnostics were done. Although this methodology is important in diagnosis, in both cases it showed certain limitations in diagnosing such rare tumors. The final diagnosis was made after carefully synthesizing the histological findings and immunohistochemical phenotype. Conclusion. An accurate classification of breast tumors on cytological preparations is not possible in case of poorly differentiated and rare tumors. A careful and accurate classification of these tumors is necessary.

Successful One-Stage Operative Resection of an Intravenous Leiomyomatosis Involving the Right-Sided Heart Chambers and Pulmonary Artery

2016 ◽  
Vol 19 (2) ◽  
pp. 064
Author(s):  
Rongjian Xu ◽  
Qi Miao ◽  
Xingrong Liu ◽  
Chaoji Zhang ◽  
Guotao Ma
Keyword(s):  
Cardiopulmonary Bypass ◽  
Pulmonary Artery ◽  
Unique Feature ◽  
Circulatory Arrest ◽  
Deep Hypothermic Circulatory Arrest ◽  
Intravenous Leiomyomatosis ◽  
Right Heart ◽  
One Stage ◽  
The Right

Intravenous leiomyomatosis (IVL) is a rare neoplastic disorder. It may extend into the right cardiac chambers, which are named after intracardiac leiomyomatosis (ICL). We describe a case of IVL extending into the right heart and pulmonary artery in a 46-year-old woman. The patient successfully underwent a one-stage operation under cardiopulmonary bypass (CPB) with deep hypothermic circulatory arrest. The patient fully recovered without major complications and did not exhibit any recurrence at the 9-month follow-up. The unique feature of this case is its involvement with the pulmonary artery, which is uncommon but potentially lethal.

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