Status Epilepticus: Work-Up and Management in Adults

2020 ◽  
Vol 40 (06) ◽  
pp. 652-660
Author(s):  
Assia Meziane-Tani ◽  
Brandon Foreman ◽  
Moshe A. Mizrahi
Keyword(s):  
United States ◽  
Status Epilepticus ◽  
Drug Administration ◽  
Baby Boomer ◽  
The United States ◽  
Morbidity And Mortality ◽  
Significant Morbidity ◽  
Neurological Emergencies ◽  
Work Up

AbstractStatus epilepticus is one of the most common neurological emergencies and is likely to have increasing prevalence in coming years given an aging “baby boomer” population in the United States. Because status epilepticus is associated with significant morbidity and mortality, identification and treatment are paramount. Care should be taken to exclude nonorganic mimics and infectious and metabolic causes. Status epilepticus can be classified into stages with associated recommendations for escalation in therapy, increasing from push-dose benzodiazepines to continuous anesthetic infusions and other nontraditional therapies. Concurrent electroencephalogram monitoring helps to identify, localize, and assess resolution of ictal patterns alongside antiseizure drug administration. A protocol is proposed for the management of status epilepticus in a step-wise fashion.

Smallpox Vaccination

PEDIATRICS ◽  
1972 ◽  
Vol 49 (6) ◽  
pp. 922-923
Author(s):  
Edward B. Shaw
Keyword(s):  
United States ◽  
Herd Immunity ◽  
The United States ◽  
Morbidity And Mortality ◽  
Routine Immunization ◽  
Smallpox Vaccination ◽  
Significant Morbidity

The zero incidence of smallpox in the United States for so many years, and the significant morbidity and mortality from vaccination, has led to the acceptable and desirable recommendation that routine immunization against smallpox be discontinued. However appropriate this step may seem, it will pose a number of new problems which will involve the pediatrician especially. (1) For many years, smallpox vaccination has been an almost sacred tenet, an immunologic gospel to the population, and has been credited with the conquest of this disease in this country—even though herd immunity could hardly be said to have existed here. Public reeducation is a hazardous matter.

scholarly journals A Case Series of Patients Coinfected With Influenza and COVID-19

2020 ◽  
Vol 8 ◽  
pp. 232470962093467 ◽  
Author(s):  
Venu Madhav Konala ◽  
Sreedhar Adapa ◽  
Srikanth Naramala ◽  
Avantika Chenna ◽  
Shristi Lamichhane ◽  
...  
Keyword(s):  
United States ◽  
Influenza Infection ◽  
Treatment Options ◽  
Case Series ◽  
The United States ◽  
Vaccine Effectiveness ◽  
Morbidity And Mortality ◽  
Significant Morbidity ◽  
Global Pandemic

Coronavirus disease 2019, also called COVID-19, is a global pandemic resulting in significant morbidity and mortality worldwide. In the United States, influenza infection occurs mainly during winter and several factors influence the burden of the disease, including circulating virus characteristics, vaccine effectiveness that season, and the duration of the season. We present a case series of 3 patients with coinfection of COVID-19 and influenza, with 2 of them treated successfully and discharged home. We reviewed the literature of patients coinfected with both viruses and discussed the characteristics, as well as treatment options.

scholarly journals Severe Maternal Morbidity and Mortality Among Indigenous Women in the United States

2020 ◽  
Vol 135 (2) ◽  
pp. 294-300 ◽  
Author(s):  
Katy B. Kozhimannil ◽  
Julia D. Interrante ◽  
Alena N. Tofte ◽  
Lindsay K. Admon
Keyword(s):  
United States ◽  
Maternal Morbidity ◽  
The United States ◽  
Indigenous Women ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Maternal Morbidity And Mortality

scholarly journals Healthcare-Associated Infections among Patients in a Large Burn Intensive Care Unit: Incidence and Pathogens, 2008–2012

2014 ◽  
Vol 35 (10) ◽  
pp. 1304-1306 ◽  
Author(s):  
David J. Weber ◽  
David van Duin ◽  
Lauren M. DiBiase ◽  
Charles Scott Hultman ◽  
Samuel W. Jones ◽  
...  
Keyword(s):  
United States ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
The United States ◽  
Burn Injuries ◽  
Morbidity And Mortality ◽  
Common Source ◽  
Healthcare Associated Infections ◽  
Burn Patients ◽  
Healthcare Associated

Burn injuries are a common source of morbidity and mortality in the United States, with an estimated 450,000 burn injuries requiring medical treatment, 40,000 requiring hospitalization, and 3,400 deaths from burns annually in the United States. Patients with severe burns are at high risk for local and systemic infections. Furthermore, burn patients are immunosuppressed, as thermal injury results in less phagocytic activity and lymphokine production by macrophages. In recent years, multidrug-resistant (MDR) pathogens have become major contributors to morbidity and mortality in burn patients.Since only limited data are available on the incidence of both device- and nondevice-associated healthcare-associated infections (HAIs) in burn patients, we undertook this retrospective cohort analysis of patients admitted to our burn intensive care unit (ICU) from 2008 to 2012.

scholarly journals Mortality after a First Episode of Status Epilepticus in the United States and Europe

Epilepsia ◽  
2005 ◽  
Vol 46 (s11) ◽  
pp. 46-48 ◽  
Author(s):  
Giancarlo Logroscino ◽  
Dale C. Hesdorffer ◽  
Gregory Cascino ◽  
W. Allen Hauser ◽  
Alessandra Coeytaux ◽  
...  
Keyword(s):  
United States ◽  
Status Epilepticus ◽  
The United States ◽  
First Episode

The Dispensatory of the United States of America

PEDIATRICS ◽  
1948 ◽  
Vol 1 (6) ◽  
pp. 846-846
Keyword(s):  
United States ◽  
Drug Administration ◽  
United States Of America ◽  
Editorial Policy ◽  
The United States ◽  
Trade Mark ◽  
British Pharmacopoeia ◽  
Therapeutic Uses ◽  
Trade Name ◽  
New Feature

This edition is based on the U. S. P. XIII, N.F. VIII, N.N.R., 1947, and the British Pharmacopoeia, 1932, and its addenda. The significant change in editorial policy is the enlargement of that portion of each monograph devoted to a discussion of therapeutic uses and dosage of drugs, and an increased emphasis placed upon precautions to be observed during drug administration. Another new feature is the inclusion of the name of the manufacturer or distributor whose trade name or trade mark of the drug being discussed. It contains complete medical and pharmaceutical information of every drug used in medicine.

Narrowing the mindware gap in medicine

Diagnosis ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Pat Croskerry
Keyword(s):  
United States ◽  
Cognitive Performance ◽  
Clinical Reasoning ◽  
Medical Errors ◽  
Medical Error ◽  
Causes Of Death ◽  
The United States ◽  
Morbidity And Mortality ◽  
Medical Educators ◽  
High Degree

Abstract Medical error is now recognized as one of the leading causes of death in the United States. Of the medical errors, diagnostic failure appears to be the dominant contributor, failing in a significant number of cases, and associated with a high degree of morbidity and mortality. One of the significant contributors to diagnostic failure is the cognitive performance of the provider, how they think and decide about the process of diagnosis. This thinking deficit in clinical reasoning, referred to as a mindware gap, deserves the attention of medical educators. A variety of specific approaches are outlined here that have the potential to close the gap.

Prehospital Treatment of Status Epilepticus in the United States

JAMA ◽  
2021 ◽  
Vol 326 (19) ◽  
pp. 1970
Author(s):  
Elan L. Guterman ◽  
James F. Burke ◽  
Karl A. Sporer
Keyword(s):  
United States ◽  
Status Epilepticus ◽  
The United States ◽  
Prehospital Treatment
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