scholarly journals Antimicrobial Resistance Patterns in Clinically Significant Isolates from Medical Wards of a Tertiary Care Hospital in North India

2020 ◽  
Vol 12 (03) ◽  
pp. 196-202
Author(s):  
Venkatesh Sudharsan Vaithiyam ◽  
Neha Rastogi ◽  
Piyush Ranjan ◽  
Niranjan Mahishi ◽  
Arti Kapil ◽  
...  

Abstract Background The global burden of infections due to multidrug-resistant organism (MDRO) has a significant impact on patients’ morbidity and mortality along with increased healthcare expenditure. Aim This article estimates the prevalence of MDRO and the spectrum of clinical infectious syndromes caused by these organisms in medical wards of a tertiary care hospital in India. Design and Methods A cross-sectional observational study was performed among patients admitted in medicine wards diagnosed with the various infectious syndromes and one or more clinically significant positive culture at a tertiary care hospital in North India over a period of 18 months. Results Out of 323 clinically significant microbiological culture isolates from 229 patients included in the study, 86 (27%) isolates showed multidrug resistance (MDR) pattern, 197 (61%) isolates showed possible extremely drug-resistance pattern, and only 40 (12%) isolates showed nonmultidrug-resistance pattern of antibiogram. Conclusion The prevalence of MRDOs is high in clinically significant culture isolates from medicine wards in India. This emphasizes the importance of appropriate antibiotic usage and implementation of antibiotic stewardship programs in this part of the world.

2020 ◽  
Vol 11 (02) ◽  
pp. 237-244
Author(s):  
Sandeep Grover ◽  
Neha Sharma ◽  
Aseem Mehra

Abstract Objective This study aimed to evaluate the prevalence of stigma for mental disorders among nursing staff in a tertiary care hospital, and the secondary objective of the study was to assess the correlation of stigma with the socio-demographic profile and previous experience with mentally ill patients. Methods This cross-sectional study was performed among the 210 nurses working in a tertiary care multispecialty teaching public sector hospital in north India. They were evaluated on community attitudes toward the mentally ill (CAMI) scale. Results About two-thirds of the participants (67.1%) were females and had done graduation (64.2%) in nursing. Nearly 50% of the study participants had an experience of working with mentally ill patients. Female had a more significant positive attitude on the domain of social restrictiveness. Authoritarianism had a significant positive correlation with benevolence and social restrictiveness domains. The benevolence domain had a significant correlation with all other domains. Social restrictiveness domain also had a significant correlation with other domains. Conclusion Nurses have a positive attitude toward mentally ill patients.


Author(s):  
Shivani Juneja ◽  
Proteesh Rana ◽  
Parvinder Chawala ◽  
Rekha Katoch ◽  
Kulvir Singh ◽  
...  

Abstract Objectives The use of Hydroxychloroquine (HCQ) prophylaxis has been recommended by the National task force constituted by the Indian Council of Medical Research (ICMR) for the prevention of corona virus disease 2019 (COVID-19) among healthcare workers (HCWs). However, this recommendation was based essentially on the preclinical data and limited clinical experience. The aim of this study was to evaluate the efficacy and safety of HCQ as a pre-exposure prophylaxis for COVID-19 infection among Indian HCWs. Methods A cross-sectional study was conducted among HCWs of a tertiary care hospital in north India. The HCQ prophylaxis was initiated among 996 HCWs and they were followed up to 8 weeks for conversion to COVID-19 positive status and any adverse drug reaction (ADR). Results About 10.3% of the study participants were tested positive for COVID-19 which was comparable to the positivity rate among HCWs not taking HCQ prophylaxis (9.7%). Conclusions HCQ was well tolerated at a weekly dose of 400 mg for 8 weeks but provided no additional benefit in prevention of COVID-19 among HCWs.


2021 ◽  
Vol 6 (2) ◽  
pp. 451-458
Author(s):  
Rajender Singh ◽  
Mangla Sood ◽  
Vipin Roach

Background: Despite benefits of breast feeding for both the infants and mothers, its prevalence has remained low worldwide. The present study was conducted to examine the knowledge and attitude towards breast feeding practices among postnatal mothers. Methodology:A cross sectional study was conducted among non-randomly selected postnatal mothers at a tertiary care hospital in North India. Data was collected through a structured online questionnaire administered on electronic tablet before discharge. Results: Among 430 females enrolled in study, majority (98.65%)of the mothers believed breast milk is best nutrition for infant. 211(95%) multipara were breastfeeders, 64 among them had breastfed for more than 2 years. Only 9 mothers had stopped BF before 6 months. However, only 301(78%) had initiated breast feeding within one hour of birth. Early initiation was higher among vaginal (50.34%) compared to Caesarean (25.7%) births. Only 40% mothers observed correct positioning and attachment of infant on breast. Higher number of antenatal visits and correct skill of latching infant on breast were significantly associated with better exclusive BF rates. 91% mothers preferred to increase suckling on breast by infant to tackle problem of inadequate breast milk output. Conclusion: Our findings showed increase knowledge and positive attitude for BF among post natal mothers delivering in hospitals. We emphasise on the importance of prenatal education to mothers and fathers on breast-feeding. We also recommend strengthening the public health education campaigns to promote breast-feeding. Keywords: Attitudes, Breast feeding, India, Infant feeding practices, Knowledge, Mothers.


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