scholarly journals Redox Changes in Amateur Race Car Drivers Before and After Racing

2017 ◽  
Vol 1 (06) ◽  
pp. E212-E219
Author(s):  
Kimberly Bjugstad ◽  
Paul Gutowski ◽  
Jennifer Pekarek ◽  
Pamela Bourg ◽  
Charles Mains ◽  
...  

AbstractDespite the unique opportunity race car driving provides to study exercise in extreme conditions, the sport of racing is under-represented. A better understanding of how racing changes physiological measures combined with driver demographics may help reduce driver risks and expand the field of driver science. This study charted the changes in heart rate, body temperature, blood pressure, static oxidation reduction potential (sORP), and antioxidant capacity in drivers before and after racing (n=23). The interaction between racing and driver characteristics on physiological variables were evaluated. Heart rate, body temperature, and sORP were elevated after racing (P<0.05). Age, cockpit temperature, experience, and speed did not correlate with physiological or oxidative measures (P>0.05). Elevated post-race sORP values were associated with higher pre-race systolic blood pressure and lower antioxidant capacity (P<0.05). We conclude that racing alters the redox response in drivers and that drivers’ pre-race systolic blood pressure and antioxidant capacity can further alter it. A better understanding of the physical and oxidative changes which result from racing may help minimize the unique risks

2020 ◽  
Vol 9 (8) ◽  
pp. e316985536
Author(s):  
Jaqueline Oliveira Barreto ◽  
Julliana Cariry Palhano Freire ◽  
Arthur Willian de Lima Brasil ◽  
Cristian Statkievicz ◽  
Francisley Ávila Souza ◽  
...  

Objective: To assess dental anxiety in patients undergoing oral surgery, as well as its impact on blood pressure and heart rate. Material and Methods: A total of 233 patients answered a socio-demographic questionnaire and another one based on the Corah dental anxiety scale. Blood pressure and heart rate were assessed at three moments while: patients were in the waiting room, immediately before and after the procedure. Results: This study revealed a prevalence of anxiety of 77.3%. There was a statistically significant difference in mean systolic blood pressure and heart rate at the three moments of the evaluation. Anxiety was prevalent in the sample and was observed from the time in the waiting room until the time when local anesthesia was performed, causing variations in systolic blood pressure and heart rate, anxiety levels decreased after the end of the service. In conclusion, we observed that oral surgery is directly related to increased anxiety, and anxiety is mainly related to the change in heart rate.


2010 ◽  
Vol 25 (6) ◽  
pp. 899-903 ◽  
Author(s):  
Akira SYOUBO ◽  
Toshio SUSAKI ◽  
Noboru HIROSE ◽  
Toshiro OKU ◽  
Kstsuhiko TACHINO

2017 ◽  
Vol 20 (2) ◽  
pp. 172-178 ◽  
Author(s):  
María J Del Sole ◽  
Pablo Nejamkin ◽  
Verónica Cavilla ◽  
Paula Schaiquevich ◽  
Laura Moreno

Objectives The objectives were to compare two different sedative combinations, xylazine–ketamine and dexmedetomidine–ketamine, for the short electroretinography (ERG) protocol and their impact on sedative effect, reversal times and physiological variables in cats. Methods Six healthy spayed female domestic cats were sedated using one of two ketamine-containing protocols: intramuscular xylazine hydrochloride (1 mg/kg) plus ketamine hydrochloride (3 mg/kg) (XK), and dexmedetomidine hydrochloride (5 µg/kg) plus ketamine hydrochloride (3 mg/kg) (DK). A short ERG protocol was recorded from the left eye of each cat under XK and DK sedation. Thirty minutes later, the effects were reversed with yohimbine or atipamezole for the XK and DK treatment, respectively. The cats were evaluated for time to recumbency, time to head elevation, and time to standing position after reversal treatments. Other variables recorded were: systolic blood pressure, cardiac rhythm, heart rate, pulse oximetry and respiratory rate. Recorded ERG variables included a- and b-wave amplitudes and implicit times under photopic, scotopic and scotopic mixed ERG conditions. Results Time to lateral recumbency with XK was shorter than for DK ( P <0.05). After reversal, head elevation and standing position times were significantly longer for the XK than the DK group ( P <0.05). Heart rate increased and systolic blood pressure decreased from baseline in both groups ( P <0.05), but there were no significant differences between treatment groups. The b-wave amplitude recorded in the photopic study of cats treated with XK was lower than in animals treated with DK ( P <0.05). No other significant differences in ERG variables were observed between treatment groups ( P >0.05). Conclusions and relevance The present study shows that XK and DK treatments are chemical restraint alternatives for ERG recording in cats, with significant differences only in the photopic b-wave amplitude.


1977 ◽  
Vol 43 (5) ◽  
pp. 801-806 ◽  
Author(s):  
D. Cousineau ◽  
R. J. Ferguson ◽  
J. de Champlain ◽  
P. Gauthier ◽  
P. Cote ◽  
...  

Coronary patients exercised on an ergometric bicycle before and after physical training. Plasma catecholamines were sampled simultaneously at the arterial and coronary sinus levels and assayed with a radioenzymatic method. The increase in the level of coronary sinus catecholamines exceeded the increase in the arterial level, indicating a liberation of catecholamines by the myocardium and an activation of the peripheral sympathetic fibers during exercise. With high work loads, these values no longer differed, suggesting that the additional increase in circulating catecholamines originate from extra-myocardial stores, presumably the adrenal medulla. Arterial catecholamine levels were significantly correlated with work loads, heart rate, changes in systolic blood pressure, and rate-pressure product. After physical training, arterial catecholamine increases for various work loads were lower; these lower elevations were associated with diminished responses in heart rate and systolic blood pressure, resulting in a lower rate-pressure product. Physical training results in diminished sympathetic responses for a given level of exercise, which could be associated with the clinical improvement of these patients.


1998 ◽  
Vol 95 (3) ◽  
pp. 269-275 ◽  
Author(s):  
Jacques-Olivier FORTRAT ◽  
Olivier NASR ◽  
Monique DUVAREILLE ◽  
Claude GHARIB

1.We studied cardiovascular variability, baroreflex and blood volume regulating hormones to determine the relative roles of autonomic regulation and hormones during blood donation. 2.The sympathetic response was studied by measuring the R–R interval and systolic blood pressure variability using coarse graining spectral analysis in eight blood donors. Beat-by-beat R–R intervals and blood pressure were recorded for 20 ;min before and 5 ;min after a whole-blood donation of 480±10 ;ml (about 7 ;ml/kg of blood volume, over 4 ;min). Plasma catecholamines, vasopressin, atrial natriuretic peptide, endothelin, active renin, osmolality, Na+, K+, haemoglobin and haematocrit were measured just before and after blood withdrawal. 3.Blood donation led to increases in the plasma catecholamines (adrenaline, 21±2 versus 35±3 ;pg/ml; noradrenaline, 229±26 versus 323±37 ;pg/ml; dopamine, 34±3 versus 66±9 ;pg/ml) and in systolic blood pressure (130±6 versus 140±5 ;mmHg). These changes were independent of ionic or slow endocrine mechanisms. Heart rate, cardiovascular variability and the spontaneous baroreflex sensitivity did not change despite the increase in blood pressure and catecholamines. Thus the peripheral vascular control was probably involved. 4.We conclude that the absence of any change in heart rate usually observed during non-hypotensive hypovolaemic stress is probably due to the sympathetic activation being counterbalanced by the high supine vagal tone at the heart and not to the heterogeneous nature of the sympathetic neural response or to changes in sympathetic and parasympathetic activity without any change in autonomic balance.


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