Implications of obesity and medical illness for major depression – a different endophenotype of major depression in obese patients?

2005 ◽  
Vol 38 (05) ◽  
Author(s):  
S Kloiber ◽  
M Ising ◽  
S Lucae ◽  
R Lieb ◽  
F Holsboer
Keyword(s):  
Major Depression ◽  
Medical Illness ◽  
Obese Patients

Defining guilt in depression: a comparison of subjects with major depression, chronic medical illness and healthy controls

2002 ◽  
Vol 68 (2-3) ◽  
pp. 307-315 ◽  
Author(s):  
Kayhan Ghatavi ◽  
Rob Nicolson ◽  
Cathy MacDonald ◽  
Sue Osher ◽  
Anthony Levitt
Keyword(s):  
Major Depression ◽  
Medical Illness ◽  
Healthy Controls ◽  
Chronic Medical Illness

Obesity and psychopathology. A study of psychiatric comorbidity among patients attending a specialist obesity unit

2009 ◽  
Vol 18 (2) ◽  
pp. 119-127 ◽  
Author(s):  
Bernardo Carpiniello ◽  
Federica Pinna ◽  
Gianluca Pillai ◽  
Valentina Nonnoi ◽  
Enrica Pisano ◽  
...  
Keyword(s):  
Mental Health ◽  
Major Depression ◽  
Mood Disorders ◽  
Clinical Sample ◽  
Psychiatric Evaluation ◽  
Routine Practice ◽  
Obese Patients ◽  
High Prevalence ◽  
Axis I ◽  
Treatment Of Obesity

SummaryAims – The study aims to evaluate the frequency of association between Axis I and II disorders according to DSMIVTR criteria and obesity, and use of mental health services in a clinical sample of patients attending a centre for the diagnosis and treatment of Obesity. Methods – 150 consecutive patients (32 Males, 118 females, mean age 44.614.3 yrs; mean BMI 35.46.2) were interviewed by means of SCID I and SCID II. Results – Lifetime Prevalence of Axis I disorders was 58% (males 50%; females 61%); the highest prevalence rate was found for Anxiety Disorders (approx 35%), whilst 30% of subjects were affected by Mood disorders, chiefly Major Depression (20%), and 18% by Eating Disorders. 28% of obese patients presented a Personality Disorder, 23% of patients being affected both by an Axis I and Axis II disorder. Mood Disorders, in particular Major Depression, were significantly prevalent among female obese. 50% of females and approx 37% males included in the sample had contacted mental health units for treatment. Conclusion – Data obtained in the present study confirm the high prevalence rates of mental disorders in obese patients seeking treatment. Specialist units should therefore include thorough psychiatric evaluation of patients as a routine practice.Declaration of Interest: The study was supported by a research grant by University of Cagliari (ex 60% funding, financial year 2006); the authors declare no conflict of interest.

scholarly journals Quality of depression treatment in Black Americans with major depression and comorbid medical illness

2014 ◽  
Vol 36 (4) ◽  
pp. 431-436 ◽  
Author(s):  
Amma A. Agyemang ◽  
Briana Mezuk ◽  
Paul Perrin ◽  
Bruce Rybarczyk
Keyword(s):  
Major Depression ◽  
Black Americans ◽  
Depression Treatment ◽  
Medical Illness

scholarly journals Depression, Anxiety and Stress among Obese Patients with Chronic Illnesses: Prevalence and Associated Factors in North East Malaysia

2019 ◽  
Vol 18 (2) ◽  
pp. 252-259
Author(s):  
Raihan Hassan ◽  
Maryam Mohd Zulkifli ◽  
Imran Ahmad ◽  
Siti Suhaila MohdYusoff
Keyword(s):  
Family History ◽  
Outpatient Clinic ◽  
Psychiatric Illness ◽  
Medical Science ◽  
High Body Mass Index ◽  
Medical Illness ◽  
Obese Patients ◽  
Factors Associated ◽  
Younger Age ◽  
History Of

Introduction: Concomitant obesity and chronic medical illness is a significant health problem in Malaysia and worldwide. The comorbid psychological impact in obese patients is associated with a social stigma and low self-esteem. The aim of this study was to determine the prevalence and the factors associated with depression, anxiety and stress in obese patients with chronic medical illnesses attending an outpatient clinic. Methods: This was a cross-sectional study among obese patients with chronic medical illnesses presenting at the Universiti Sains Malaysia Hospital outpatient clinic. A total of 274 patients were involved. The 21-item Depression, Anxiety and Stress Scale questionnaire was used, and the results were evaluated using single and multiple logistic regression analyses. Results: The prevalences of depression, anxiety and stress among the obese patients with chronic medical illnesses were 13.9%, 23.4% and 10.9%, respectively. Younger age [p=0.003, adjusted odds ratio (AOR),1.0; 95%confidence interval (CI),0.91–0.98], unemployed employment(p=0.013, AOR,3.7;95% CI,1.32–10.09) and smoking (p=0.022, AOR,3.2; 95% CI,1.18–8.55) were associated with depression. No formal education (p=0.011, AOR,5.7; 95%CI,1.49–21.89), high body mass index (p=0.029, AOR,1.1;95% CI,1.01–1.13) and family history of psychiatric illness (p=0.018, AOR,5.1; 95% CI,1.33–19.56) were associated with anxiety. Stress was strongly associated with females (p=0.004, AOR,5.0; 95% CI,1.70–15.13) and smoking(p=0.002, AOR,6.5; 95% CI,2.03–20.7). Conclusion: Interestingly, younger age group was associated with depression. Current smokers, no education, family history of psychiatric illness and female sex were significantly associated with anxiety and stress. This notifies new emerging knowledge on factors associated with obese patients that would empower the development of effective preventive strategies for it. Bangladesh Journal of Medical Science Vol.18(2) 2019 p.252-259

Religious vs. Conventional Cognitive Behavioral Therapy for Major Depression in Persons With Chronic Medical Illness

2015 ◽  
Vol 203 (4) ◽  
pp. 243-251 ◽  
Author(s):  
Harold G. Koenig ◽  
Michelle J. Pearce ◽  
Bruce Nelson ◽  
Sally F. Shaw ◽  
Clive J. Robins ◽  
...  
Keyword(s):  
Major Depression ◽  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Medical Illness ◽  
Chronic Medical Illness

Antidepressant treatment of cytokine-induced mood disorders

2002 ◽  
Vol 14 (6) ◽  
pp. 336-343 ◽  
Author(s):  
Charles L Raison ◽  
Michael Marcin ◽  
Andrew H Miller
Keyword(s):  
Major Depression ◽  
Immune Cell ◽  
Antidepressant Treatment ◽  
Sickness Behavior ◽  
Laboratory Animals ◽  
Interferon Α ◽  
Medical Illness ◽  
Hepatitis C Infection ◽  
Induced Mood ◽  
Second Messenger Pathways

Significant evidence suggests that the immune system is capable of profoundly affecting central nervous system (CNS) functioning in ways that may contribute to the development and expression of neuropsychiatric disorders, including disorders of mood. This paper reviews evidence that the production of proinflammatory cytokines, whether in the context of therapeutic administration (e.g. interferon-α-2b for hepatitis C infection) or medical illness, induces a state of sickness behavior that closely resembles major depression. Antidepressants have been shown to abolish or attenuate cytokine-induced sickness behavior in laboratory animals and to protect against the development of major depression in the context of therapeutic cytokine administration in humans. Potential mechanisms by which antidepressants ameliorate depressive and/or sickness symptoms in the context of immune activation include direct effects on immune cell functioning, as well as modulatory effects on monoamine neurotransmitters, intracellular second messenger pathways and the neuroendocrine system, in particular the hypothalamic–pituitary–adrenal axis.

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