Preparation and evaluation of N, N1-methylenebisacrylamide crosslinked polymer for the controlled release of water and fertilizer in agriculture sector

2021 ◽  
Author(s):  
V. Dhanapal ◽  
P. Subhapriya ◽  
N. Arunadevi ◽  
S. Radjarejesri
Author(s):  
Sreeja C Nair ◽  
Karthika Ramesh ◽  
Krishnapriya M ◽  
Asha Paul

ABSTRACTObjective: The objective behind our study is that a mucoadhesive rectal hydrogel chitosan sodium alginate carbamazepine (CBZ) microspheres forthe purpose of controlled release for the treatment of epilepsy to avoid the possible side effects.Methods: The study was conducted to formulate controlled release chitosan sodium alginate CBZ microspheres with the dispersion of CBZ into thenatural polymers chitosan and sodium alginate forming microspheres conducting along with their evaluation studies.Results: The formulated microspheres were subjected to various evaluation parameters, and all the physical parameters examined are within theacceptable limits. Further, the optimized microsphere formulation (CM5) was characterized. Hence, the developed optimized microsphere formulation(CM5) seems to be a viable substitute to conventional drug delivery system for the effective management of epilepsy.Conclusion: The prepared formulation also provides a desired CBZ loaded sodium alginate microspheres with the controlled release drug delivery.Keywords: Carbamazepine, Sodium alginate microspheres, Particle size.


1995 ◽  
Vol 10 (2) ◽  
pp. 121-125
Author(s):  
Kiyoshi Niwa ◽  
Tomohiro Takaya ◽  
Shinichiro Kondo ◽  
Yoko Takeshita ◽  
Kanji Takada

1984 ◽  
Vol 10 (10) ◽  
pp. 1597-1616 ◽  
Author(s):  
Y. Pongpaibul ◽  
J. C. Price ◽  
C. W. Whitworth

2008 ◽  
Vol 58 (3) ◽  
pp. 309-316 ◽  
Author(s):  
Anita Lalwani ◽  
Jolly Parikh

Preparation and evaluation of an ispaghula based directly compressible matrixing agent for controlled releaseThe objective of the present investigation was to prepare and evaluate an ispaghula husk based directly compressible (DC) adjuvant that can be used as matrixing agent using an agglomeration technique. Addition of hydroxypropyl methylcellulose was found necessary to improve cohesion. Lactose (X1), calcium hydrogen phosphate dihydrate (X2) and Avicel PH101 (X3), used along with ispaghula in preparation of agglomerates, were selected as three independent variables in a simplex lattice design affecting compressional and dissolution characteristics of the drug from the DC adjuvant. The agglomerates were evaluated for their flow properties. Tablets were prepared using 70% agglomerates and 30% acetaminophen, a poorly compressible drug, and were subjected toin vitrodrug release study. Amounts of the drug released at the end of 60 min (Y60), 300 min (Y300) and 480 min (Y480) were selected as dependent variables in a simplex lattice design. Batch IH05 that contained lactose and calcium hydrogen phosphate dihydrate in a 1:2 ratio could control the release for 12 hours and thus form the basis for twice a-day-dosing.


Sign in / Sign up

Export Citation Format

Share Document