Synthesis and Self-Assembly of a Peptide - Amphiphile as a Drug Delivery Vehicle

2013 ◽  
Vol 66 (1) ◽  
pp. 23 ◽  
Author(s):  
Soo Jung Son ◽  
Margaret A. Brimble ◽  
Sunghyun Yang ◽  
Paul W. R. Harris ◽  
Tom Reddingius ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Glutamic Acid ◽  
Long Range ◽  
Self Assembly ◽  
The Self ◽  
Long Range Order ◽  
Delivery Vehicle ◽  
Peptide Amphiphile ◽  
Drug Delivery Vehicle ◽  
Hydrophobic Moiety

The formation of functional liposomes by the self assembly of a peptide–amphiphile that comprises the neuroprotective tripeptide motif glycyl-prolyl-glutamic acid linked to a hydrophobic moiety is reported. The self-assembled peptide–lipid conjugate displays long range order and can be dispersed as nanometre sized particles.

scholarly journals Self-Assembly Mechanism of a Peptide-Based Drug Delivery Vehicle

ACS Omega ◽  
2018 ◽  
Vol 3 (3) ◽  
pp. 3143-3155 ◽  
Author(s):  
Gopal Pandit ◽  
Karabi Roy ◽  
Umang Agarwal ◽  
Sunanda Chatterjee
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Assembly Mechanism

scholarly journals Chiral self-sorting of active semiflexible filaments with intrinsic curvature

Soft Matter ◽  
2021 ◽  
Author(s):  
Jeffrey M Moore ◽  
Matthew Glaser ◽  
Meredith D. Betterton
Keyword(s):  
Long Range ◽  
Self Assembly ◽  
Range Order ◽  
The Self ◽  
Long Range Order ◽  
Active Matter ◽  
Many Body ◽  
Intrinsic Curvature ◽  
Dynamic Structures ◽  
Many Body Interactions

Many-body interactions in systems of active matter can cause particles to move collectively and self-organize into dynamic structures with long-range order. In cells, the self-assembly of cy- toskeletal filaments is...

scholarly journals Pillar[5]arene-based amphiphilic supramolecular brush copolymers: fabrication, controllable self-assembly and application in self-imaging targeted drug delivery

2016 ◽  
Vol 7 (40) ◽  
pp. 6178-6188 ◽  
Author(s):  
Guocan Yu ◽  
Run Zhao ◽  
Dan Wu ◽  
Fuwu Zhang ◽  
Li Shao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Self Assembly ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Targeted Drug

Here we construct the first pillararene-based amphiphilic supramolecular brush copolymer, which can be utilized as a targeting self-imaging drug delivery vehicle.

Synthesis of PMMA-b-PS Block Copolymer by Emulsion ATRP and its Self-Assembly Property

2013 ◽  
Vol 705 ◽  
pp. 115-119
Author(s):  
Bao Yong Tian ◽  
Er Jun Tang ◽  
Miao Yuan ◽  
Rui Xia Hao ◽  
Cun Man Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Self Assembly ◽  
Potential Application ◽  
Morphological Characteristic ◽  
Living Polymerization ◽  
The Self ◽  
Emulsion System ◽  
Copolymer Concentration ◽  
Ft Ir

The well-defined block copolymer PMMA-b-PS was prepared by two-step ATRP in emulsion system. GPC results indicate that Mn increased linearly with conversion and polydispersity remained relatively narrow. It presents the characteristics of living polymerization in emulsion system. FT-IR demonstrated that block copolymer PMMA-b-PS could be successfully synthesized by ATRP with macroinitiator PMMA-Cl in emulsion system. The morphological characteristic of the self-assembly depends on the block copolymer concentration and transforms between spheres and rodlike micelles. The property indicates a perfect potential application in drug delivery materials.

scholarly journals Application of Pickering Emulsion with Cyclodextrin as an Emulsifier to a Transdermal Drug Delivery Vehicle

2019 ◽  
Vol 42 (1) ◽  
pp. 116-122 ◽  
Author(s):  
Hiroyuki Taguchi ◽  
Haruki Tanaka ◽  
Kaname Hashizaki ◽  
Yoshihiro Saito ◽  
Makiko Fujii
Keyword(s):  
Drug Delivery ◽  
Transdermal Drug Delivery ◽  
Pickering Emulsion ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle

2018 ◽  
Vol 54 (55) ◽  
pp. 7617-7620 ◽  
Author(s):  
Kristina Roth Stefaniak ◽  
Charity C. Epley ◽  
Joshua J. Novak ◽  
Margaret L. McAndrew ◽  
Hannah D. Cornell ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Small Molecules ◽  
Metal Organic Framework ◽  
Delivery Vehicle ◽  
Triggered Release ◽  
Drug Delivery Vehicle ◽  
Metal Organic ◽  
Organic Framework

A nano metal–organic-framework (nanoMOF) was employed as a first-of-its kind drug delivery vehicle (DDV) for the photo-controlled release of therapeutics with simultaneous breakdown of the carrier into small molecules.

Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery

2018 ◽  
Vol 6 (18) ◽  
pp. 2758-2768 ◽  
Author(s):  
Hongzhao Qi ◽  
Lijun Yang ◽  
Xueping Li ◽  
Qi Zhan ◽  
Donglin Han ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Clinical Translation ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Related Drug ◽  
Targeted Drug

A new exosome-related drug delivery vehicle was explored based on the “STOP” criteria, dramatically promoting the clinical translation of exosomes.

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