Synthesis of Cyclopropyl Amino Acid Derivatives
Keyword(s):
Derivatives of α,β-methanovaline, α,β-methanophenylalanine and β-methyl-αβmethanoalanine have been prepared by regioselective side-chain functionalization of suitably protected amino acid derivatives, followed by cyclization with either sodium hydride or 1,8-diazabicyclo[5.4.O]undec-7-ene. The approach used in this work illustrates a method for the synthesis of cyclopropyl amino acid derivatives which is complementary to existing procedures.
2014 ◽
Vol 14
(7)
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pp. 984-993
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Keyword(s):
1959 ◽
Vol 81
(2)
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pp. 377-382
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1972 ◽
Vol 61
(3)
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pp. 477-478
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1955 ◽
Vol 77
(21)
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pp. 5721-5725
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