Transmembrane signaling by a chimera of the Escherichia coli aspartate receptor and the human insulin receptor.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.86.15.5683 ◽

1989 ◽

Vol 86 (15) ◽

pp. 5683-5687 ◽

Author(s):

G. R. Moe ◽

G. E. Bollag ◽

D. E. Koshland

Keyword(s):

Escherichia Coli ◽

Insulin Receptor ◽

Human Insulin ◽

Transmembrane Signaling ◽

Aspartate Receptor ◽

Human Insulin Receptor

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Linking functional domains of the human insulin receptor with the bacterial aspartate receptor.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.83.21.8137 ◽

1986 ◽

Vol 83 (21) ◽

pp. 8137-8141 ◽

Author(s):

L. Ellis ◽

D. O. Morgan ◽

D. E. Koshland ◽

E. Clauser ◽

G. R. Moe ◽

...

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Functional Domains ◽

Aspartate Receptor ◽

Human Insulin Receptor

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Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.84.15.5101 ◽

1987 ◽

Vol 84 (15) ◽

pp. 5101-5105 ◽

Author(s):

L. Ellis ◽

D. O. Morgan ◽

S. M. Jong ◽

L. H. Wang ◽

R. A. Roth ◽

...

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Transmembrane Signaling ◽

Ovary Cells ◽

Human Insulin Receptor

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Mutation of the High Cysteine Region of the Human Insulin Receptor α-Subunit Increases Insulin Receptor Binding Affinity and Transmembrane Signaling

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)71563-9 ◽

1989 ◽

Vol 264 (27) ◽

pp. 15900-15904 ◽

Author(s):

R Rafaeloff ◽

R Patel ◽

C Yip ◽

I D Goldfine ◽

D M Hawley

Keyword(s):

Insulin Receptor ◽

Binding Affinity ◽

Human Insulin ◽

Receptor Binding ◽

Transmembrane Signaling ◽

Receptor Binding Affinity ◽

Insulin Receptor Binding ◽

Human Insulin Receptor

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Faculty Opinions recommendation of Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732691104.793557409 ◽

2019 ◽

Author(s):

M Amin Arnaout ◽

Johannes van Agthoven

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Full Length ◽

Transmembrane Signaling ◽

Human Insulin Receptor

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Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41806-6 ◽

1992 ◽

Vol 267 (27) ◽

pp. 19521-19528 ◽

Author(s):

A.L. Frattali ◽

J.L. Treadway ◽

J.E. Pessin

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Beta Subunit ◽

Transmembrane Signaling ◽

Receptor Kinase ◽

Kinase Activation ◽

Human Insulin Receptor ◽

Insulin Receptor Kinase

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Human insulin-receptor gene. Partial sequence and amplification of exons by polymerase chain reaction

Diabetes ◽

10.2337/diabetes.39.1.123 ◽

1990 ◽

Vol 39 (1) ◽

pp. 123-128 ◽

Author(s):

S. Seino ◽

M. Seino ◽

G. I. Bell

Keyword(s):

Polymerase Chain Reaction ◽

Insulin Receptor ◽

Human Insulin ◽

Receptor Gene ◽

Partial Sequence ◽

Chain Reaction ◽

Insulin Receptor Gene ◽

Human Insulin Receptor ◽

Polymerase Chain

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Substitution of lysine for asparagine at position 15 in the alpha-subunit of the human insulin receptor. A mutation that impairs transport of receptors to the cell surface and decreases the affinity of insulin binding.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)30636-1 ◽

1990 ◽

Vol 265 (31) ◽

pp. 19143-19150

Author(s):

T Kadowaki ◽

H Kadowaki ◽

D Accili ◽

S.I. Taylor

Keyword(s):

Cell Surface ◽

Insulin Receptor ◽

Human Insulin ◽

Insulin Binding ◽

Alpha Subunit ◽

Human Insulin Receptor

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Deletion analysis of the human insulin receptor ectodomain reveals independently folded soluble subdomains and insulin binding by a monomeric alpha-subunit.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)38291-2 ◽

1990 ◽

Vol 265 (22) ◽

pp. 13248-13253 ◽

Author(s):

E M Schaefer ◽

K Siddle ◽

L Ellis

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Insulin Binding ◽

Deletion Analysis ◽

Alpha Subunit ◽

Human Insulin Receptor

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Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)50389-1 ◽

1992 ◽

Vol 267 (13) ◽

pp. 9065-9070

Author(s):

Y Takata ◽

N.J. Webster ◽

J.M. Olefsky

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Intracellular Signaling ◽

Human Insulin Receptor ◽

Carboxyl Terminal ◽

Tyrosine Autophosphorylation

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Identification of retinal insulin receptors using site-specific antibodies to a carboxyl-terminal peptide of the human insulin receptor alpha-subunit. Up-regulation of neuronal insulin receptors in diabetes.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)38266-8 ◽

1990 ◽

Vol 265 (29) ◽

pp. 18030-18034

Author(s):

S A Rosenzweig ◽

C Zetterström ◽

A Benjamin

Keyword(s):

Insulin Receptor ◽

Human Insulin ◽

Insulin Receptors ◽

Alpha Subunit ◽

Site Specific ◽

Specific Antibodies ◽

Receptor Alpha ◽

Human Insulin Receptor ◽

Carboxyl Terminal

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