GβγSubunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor

Louis M. Luttrell; Tim van Biesen; Brian E. Hawes; Walter J. Koch; Kazushige Touhara; Robert J. Lefkowitz

doi:10.1074/jbc.270.28.16495

GβγSubunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.270.28.16495 ◽

1995 ◽

Vol 270 (28) ◽

pp. 16495-16498 ◽

Cited By ~ 156

Author(s):

Louis M. Luttrell ◽

Tim van Biesen ◽

Brian E. Hawes ◽

Walter J. Koch ◽

Kazushige Touhara ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Tyrosine Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

Download Full-text

Inhibition of insulin-like growth factor-I mitogenic action by zinc chelation is associated with a decreased mitogen-activated protein kinase activation in RAT-1 fibroblasts

FEBS Letters ◽

10.1016/s0014-5793(99)00419-6 ◽

1999 ◽

Vol 449 (2-3) ◽

pp. 284-288 ◽

Cited By ~ 17

Author(s):

Donatienne Lefebvre ◽

Charlotte M. Boney ◽

Jean-Marie Ketelslegers ◽

Jean-Paul Thissen

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Kinase Activation ◽

Factor I ◽

Protein Kinase Activation ◽

Mitogenic Action ◽

Mitogen Activated Protein ◽

Zinc Chelation

Download Full-text

Insulin-like Growth Factor-I-mediated Neurite Outgrowthin VitroRequires Mitogen-activated Protein Kinase Activation

Journal of Biological Chemistry ◽

10.1074/jbc.272.34.21268 ◽

1997 ◽

Vol 272 (34) ◽

pp. 21268-21273 ◽

Cited By ~ 113

Author(s):

Bhumsoo Kim ◽

Phillip S. Leventhal ◽

Alan R. Saltiel ◽

Eva L. Feldman

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Kinase Activation ◽

Factor I ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Growth Factor I

Download Full-text

A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1

Journal of Biological Chemistry ◽

10.1074/jbc.272.35.22330 ◽

1997 ◽

Vol 272 (35) ◽

pp. 22330-22339 ◽

Cited By ~ 329

Author(s):

Monsif Bouaboula ◽

Sylvie Perrachon ◽

Laura Milligan ◽

Xavier Canat ◽

Murielle Rinaldi-Carmona ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Cannabinoid Receptor ◽

Inverse Agonist ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

Download Full-text

The lipid raft proteins flotillins/reggies interact with Gαq and are involved in Gq-mediated p38 mitogen-activated protein kinase activation through tyrosine kinase

Cellular Signalling ◽

10.1016/j.cellsig.2007.01.012 ◽

2007 ◽

Vol 19 (6) ◽

pp. 1301-1308 ◽

Cited By ~ 43

Author(s):

Yo Sugawara ◽

Hiroko Nishii ◽

Tomoko Takahashi ◽

Junji Yamauchi ◽

Norikazu Mizuno ◽

...

Keyword(s):

Protein Kinase ◽

Tyrosine Kinase ◽

Lipid Raft ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

Download Full-text

Characterization of platelet-derived growth factor-induced p38 mitogen-activated protein kinase activation in vascular smooth muscle cells

European Journal of Clinical Investigation ◽

10.1046/j.1365-2362.2001.00865.x ◽

2001 ◽

Vol 31 (8) ◽

pp. 672-680 ◽

Cited By ~ 11

Author(s):

H. Yamaguchi ◽

M. Igarashi ◽

A. Hirata ◽

H. Tsuchiya ◽

S. Susa ◽

...

Keyword(s):

Smooth Muscle ◽

Growth Factor ◽

Protein Kinase ◽

Vascular Smooth Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Platelet Derived Growth Factor ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

Download Full-text

Uncoupling Ligand-dependent and -independent Mechanisms for Mitogen-activated Protein Kinase Activation by the Murine Ron Receptor Tyrosine Kinase

Journal of Biological Chemistry ◽

10.1074/jbc.m505737200 ◽

2005 ◽

Vol 280 (42) ◽

pp. 35098-35107 ◽

Cited By ~ 17

Author(s):

Xin Wei ◽

Shuang Ni ◽

Pamela H. Correll

Keyword(s):

Protein Kinase ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Ron Receptor

Download Full-text

Protein kinase A activity is required for depolarization-induced proline-rich tyrosine kinase 2 and mitogen-activated protein kinase activation in PC12 cells

Neuroscience Letters ◽

10.1016/s0304-3940(00)01313-6 ◽

2000 ◽

Vol 290 (1) ◽

pp. 25-28 ◽

Cited By ~ 9

Author(s):

Jae Hong Park ◽

Joong Kyu Park ◽

Kee Won Bae ◽

Hwan Tae Park

Keyword(s):

Protein Kinase ◽

Tyrosine Kinase ◽

Protein Kinase A ◽

Pc12 Cells ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Tyrosine Kinase 2 ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Kinase A

Download Full-text

Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway

British Journal of Pharmacology ◽

10.1038/sj.bjp.0703952 ◽

2001 ◽

Vol 132 (8) ◽

pp. 1657-1664 ◽

Cited By ~ 38

Author(s):

Yasunari Kanda ◽

Katsushige Mizuno ◽

Yasutomi Kuroki ◽

Yasuhiro Watanabe

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Protein Kinase ◽

Growth Factor Receptor ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Epidermal Growth ◽

Receptor Transactivation

Download Full-text

Mycophenolic Acid Inhibits Platelet-Derived Growth Factor-Induced Reactive Oxygen Species and Mitogen-Activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells

American Journal of Transplantation ◽

10.1111/j.1600-6143.2004.00610.x ◽

2004 ◽

Vol 4 (12) ◽

pp. 1982-1990 ◽

Cited By ~ 43

Author(s):

Jehyun Park ◽

Hunjoo Ha ◽

Jiyeon Seo ◽

Myoung Soo Kim ◽

Hae Jin Kim ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Smooth Muscle ◽

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Platelet Derived Growth Factor ◽

Oxygen Species ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

Download Full-text

8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor

British Journal of Cancer ◽

10.1038/sj.bjc.6690820 ◽

1999 ◽

Vol 81 (7) ◽

pp. 1134-1141 ◽

Cited By ~ 15

Author(s):

A Budillon ◽

E Di Gennaro ◽

M Caraglia ◽

D Barbarulo ◽

A Abbruzzese ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Cell Growth ◽

Epidermal Growth Factor ◽

Growth Stimulation ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Epidermal Growth

Download Full-text