scholarly journals Interleukin-1 Enhances the Ability of Cultured Human Umbilical Vein Endothelial Cells to Oxidize Linoleic Acid

1995 ◽  
Vol 270 (29) ◽  
pp. 17279-17286 ◽  
Author(s):  
Mercedes Camacho ◽  
Nuria Godessart ◽  
Rosa Antón ◽  
Montserrat Garca ◽  
Lus Vila
1992 ◽  
Vol 67 (04) ◽  
pp. 473-477 ◽  
Author(s):  
Kjell Sverre Pettersen ◽  
Merete Thune Wiiger ◽  
Nobuhiro Narahara ◽  
Kiyoshi Andoh ◽  
Gustav Gaudernack ◽  
...  

SummaryIncubation of human umbilical vein endothelial cells with one of the following compounds: endotoxin, recombinant interleukin-1β, recombinant tumor necrosis factor α, allogenic lymphocyte subpopulations or phorbol ester resulted in significant induction of tissue factor synthesis. Diacylglycerol had the same effect and also enhanced synergistically the induction caused by endotoxin and interleukin-1β. Two different inhibitors of protein kinase C, H7 and sphingosine, inhibited tissue factor synthesis at concentrations which did not depress protein synthesis in general, suggesting that protein kinase C is involved in the processes leading to tissue factor synthesis. Cells down-regulated for the tissue factor response to TPA responded essentially normally to endotoxin and interleukin-1 with regard to tissue factor synthesis.


2004 ◽  
Vol 70 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Michiharu Tanabe ◽  
Sadaharu Tabuchi ◽  
Masato Iwatsuki ◽  
Masamichi Kurosaki ◽  
Hideki Kamitani ◽  
...  

1997 ◽  
Vol 40 (11) ◽  
pp. 2030-2038 ◽  
Author(s):  
Michel de Bandt ◽  
Véronique Ollivier ◽  
Catherine Babin-Chevaye ◽  
Fouzi Khechaï ◽  
Dominique de Prost ◽  
...  

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