Interaction of Glucocorticoid Receptor (GR) with Estrogen Receptor (ER) α and Activator Protein 1 (AP1) in Dexamethasone-mediated Interference of ERα Activity

Sudipan Karmakar; Yetao Jin; Akhilesh K. Nagaich

doi:10.1074/jbc.m113.473819

Interaction of Glucocorticoid Receptor (GR) with Estrogen Receptor (ER) α and Activator Protein 1 (AP1) in Dexamethasone-mediated Interference of ERα Activity

Journal of Biological Chemistry ◽

10.1074/jbc.m113.473819 ◽

2013 ◽

Vol 288 (33) ◽

pp. 24020-24034 ◽

Cited By ~ 69

Author(s):

Sudipan Karmakar ◽

Yetao Jin ◽

Akhilesh K. Nagaich

Keyword(s):

Estrogen Receptor ◽

Glucocorticoid Receptor ◽

Activator Protein 1 ◽

Activator Protein

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Genome-Wide Mapping of Estrogen Receptor-β–Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1

Cancer Research ◽

10.1158/0008-5472.can-09-4407 ◽

2010 ◽

Vol 70 (12) ◽

pp. 5174-5183 ◽

Cited By ~ 49

Author(s):

Chunyan Zhao ◽

Hui Gao ◽

Yawen Liu ◽

Zoi Papoutsi ◽

Sadaf Jaffrey ◽

...

Keyword(s):

Estrogen Receptor ◽

Transcription Factor ◽

Cross Talk ◽

Estrogen Receptor Β ◽

Activator Protein 1 ◽

Activator Protein ◽

Genome Wide ◽

Binding Regions

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pS2 Gene Expression in HepG2 cells: Complex Regulation through Crosstalk between the Estrogen Receptor α, an Estrogen-Responsive Element, and the Activator Protein 1 Response Element

Molecular Pharmacology ◽

10.1124/mol.61.6.1273 ◽

2002 ◽

Vol 61 (6) ◽

pp. 1273-1283 ◽

Cited By ~ 26

Author(s):

Tomas Barkhem ◽

Lars-Arne Haldosén ◽

Jan-Åke Gustafsson ◽

Stefan Nilsson

Keyword(s):

Gene Expression ◽

Estrogen Receptor ◽

Hepg2 Cells ◽

Estrogen Receptor Α ◽

Activator Protein 1 ◽

Response Element ◽

Activator Protein ◽

Estrogen Responsive Element ◽

Complex Regulation ◽

Responsive Element

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Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Nucleic Acids Research ◽

10.1093/nar/gkx509 ◽

2017 ◽

Vol 45 (14) ◽

pp. 8596-8608 ◽

Cited By ~ 24

Author(s):

Emily R. Weikum ◽

Ian Mitchelle S. de Vera ◽

Jerome C. Nwachukwu ◽

William H. Hudson ◽

Kendall W. Nettles ◽

...

Keyword(s):

Glucocorticoid Receptor ◽

Activator Protein 1 ◽

Inflammatory Genes ◽

Activator Protein ◽

Recognition Motifs

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Suppression of Granulocyte-Macrophage Colony-Stimulating Factor Expression by Glucocorticoids Involves Inhibition of Enhancer Function by the Glucocorticoid Receptor Binding to Composite NF-AT/Activator Protein-1 Elements

The Journal of Immunology ◽

10.4049/jimmunol.167.5.2502 ◽

2001 ◽

Vol 167 (5) ◽

pp. 2502-2510 ◽

Cited By ~ 22

Author(s):

Philip J. Smith ◽

David J. Cousins ◽

Young-Koo Jee ◽

Dontcho Z. Staynov ◽

Tak H. Lee ◽

...

Keyword(s):

Glucocorticoid Receptor ◽

Receptor Binding ◽

Activator Protein 1 ◽

Colony Stimulating Factor ◽

Activator Protein ◽

Factor Expression ◽

Macrophage Colony Stimulating Factor ◽

Enhancer Function ◽

Macrophage Colony ◽

Stimulating Factor

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Receptor-Interacting Protein 140 Binds c-Jun and Inhibits Estradiol-Induced Activator Protein-1 Activity by Reversing Glucocorticoid Receptor-Interacting Protein 1 Effect

Molecular Endocrinology ◽

10.1210/me.2002-0324 ◽

2003 ◽

Vol 17 (2) ◽

pp. 287-299 ◽

Cited By ~ 23

Author(s):

Catherine Teyssier ◽

Karine Belguise ◽

Florence Galtier ◽

Vincent Cavailles ◽

Dany Chalbos

Keyword(s):

Glucocorticoid Receptor ◽

Activator Protein 1 ◽

Interacting Protein ◽

Activator Protein

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The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

Endocrine Reviews ◽

10.1210/er.2002-0006 ◽

2003 ◽

Vol 24 (4) ◽

pp. 488-522 ◽

Cited By ~ 557

Author(s):

Karolien De Bosscher ◽

Wim Vanden Berghe ◽

Guy Haegeman

Keyword(s):

Glucocorticoid Receptor ◽

Molecular Mechanisms ◽

Nuclear Factor Κb ◽

Gene Repression ◽

Nuclear Factor ◽

Activator Protein 1 ◽

Activator Protein

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Aberrant Expression of Fra-1 in Estrogen Receptor-negative Breast Cancers and Suppression of their Propagation In Vivo by Ascochlorin, an Antibiotic that Inhibits Cellular Activator Protein-1 Activity

The Journal of Antibiotics ◽

10.1038/ja.2007.87 ◽

2007 ◽

Vol 60 (11) ◽

pp. 682-689 ◽

Cited By ~ 16

Author(s):

Hiroo Nakajima ◽

Naruhiko Mizuta ◽

Koichi Sakaguchi ◽

Ikuya Fujiwara ◽

Mitsuhiko Mizuta ◽

...

Keyword(s):

Estrogen Receptor ◽

Activator Protein 1 ◽

Breast Cancers ◽

Aberrant Expression ◽

Activator Protein ◽

Estrogen Receptor Negative

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Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1

Biochemical Pharmacology ◽

10.1016/j.bcp.2013.05.025 ◽

2013 ◽

Vol 86 (3) ◽

pp. 401-409 ◽

Cited By ~ 11

Author(s):

María Laura Ruiz ◽

Juan Pablo Rigalli ◽

Agostina Arias ◽

Silvina Stella Maris Villanueva ◽

Claudia Banchio ◽

...

Keyword(s):

Estrogen Receptor ◽

Multidrug Resistance ◽

Estrogen Receptor Α ◽

Activator Protein 1 ◽

Activator Protein

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Identification of Endogenous Glucocorticoid Repressed Genes Differentially Regulated by a Glucocorticoid Receptor Mutant Able to Separate between Nuclear Factor-κB and Activator Protein-1 Repression

Molecular Pharmacology ◽

10.1124/mol.104.005801 ◽

2004 ◽

Vol 67 (3) ◽

pp. 815-826 ◽

Cited By ~ 34

Author(s):

Lars-Göran Bladh ◽

Johan Lidén ◽

Karin Dahlman-Wright ◽

Mark Reimers ◽

Stefan Nilsson ◽

...

Keyword(s):

Glucocorticoid Receptor ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Activator Protein 1 ◽

Activator Protein ◽

Receptor Mutant

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Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor–Negative Mammary Tumors

Cancer Prevention Research ◽

10.1158/1940-6207.capr-08-0034 ◽

2008 ◽

Vol 1 (1) ◽

pp. 45-55 ◽

Cited By ~ 11

Author(s):

Qiang Shen ◽

Ivan P. Uray ◽

Yuxin Li ◽

Yun Zhang ◽

Jamal Hill ◽

...

Keyword(s):

Estrogen Receptor ◽

Transcription Factor ◽

Mammary Tumors ◽

Activator Protein 1 ◽

Activator Protein ◽

Estrogen Receptor Negative

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