scholarly journals Erythrocyte cell membrane phospholipid levels compared against reported dietary intakes of polyunsaturated fatty acids in pregnant Mexican women

2002 ◽  
Vol 5 (6a) ◽  
pp. 931-937 ◽  
Author(s):  
Maria-Socorro Parra ◽  
Lourdes Schnaas ◽  
Mohsen Meydani ◽  
Estela Perroni ◽  
Sandra Martíanez ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Cell Membrane ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake ◽  
Pregnant Women ◽  
Pearson Correlation ◽  
Membrane Phospholipid ◽  
Mexican Women ◽  
Dietary Intakes ◽  
Tuna Fish

AbstractObjective:To evaluate the validity of a food-frequency questionnaire (FFQ) for assessment of the dietary intakes of polyunsaturated fatty acids (PUFAs) against a biochemical marker of fat intake, erythrocyte cell membrane phospholipid levels, during pregnancy.Design:Cross-sectional analysis.Setting:Developmental Neurobiology Department, National Institute of Perinatology, Mexico City.Subjects:One hundred forty-six healthy pregnant women during the last trimester of pregnancy. Among women enrolled, the first 35 pregnant women (24%) had their erythrocytes analysed for fatty acid status.Methods:We administered an FFQ and compared intakes of PUFAs against their erythrocyte cell membrane concentrations, processed by gas chromatography.Results:Pearson correlation coefficients among α-linolenic acid (ALN), docosahexaenoic acid (DHA) and eicosapentaenoic acid in erythrocyte cell membranes against their crude dietary counterparts were 0.32, 0.35 and 0.36 (each P < 0.05). In a simple linear regression, erythrocyte DHA and arachidonic acid (AA) were significantly related to their respective dietary intakes (β = 0.30, 95% confidence interval (CI): 0.007–0.60, P = 0.045 for DHA; β = 0.49, 95% CI: 0.010–0.98, P = 0.044 for AA). Erythrocyte cell membrane ALN concentration (%/total) was only marginally related to ALN dietary intake (mg day−1) (β = 0.52, 95% CI: −0.020–1.10, P = 0.061). However, after adjustment for long-chain n–3 PUFA/AA, this association reached significance (β = 0.44, 95% CI: 0.026–0.825, P = 0.038). Main dietary sources for n–3 PUFAs were canned tuna fish and fresh catfish; for n–6 these were eggs and cow's milk. The use of this FFQ in these pregnant Mexican women provided estimates of average long-term intakes of PUFAs and correlated reasonably well with their erythrocyte cell membrane phospholipid status. However, we need to consider that, during pregnancy, there is a faster turnover of PUFAs from fat storage that may modify the profile of erythrocyte PUFAs and lower the correlation between dietary intake and erythrocyte PUFAs.

scholarly journals Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women

2010 ◽  
Vol 7 (2) ◽  
pp. 140-147 ◽  
Author(s):  
Socorro Parra-Cabrera ◽  
Aryeh D. Stein ◽  
Meng Wang ◽  
Reynaldo Martorell ◽  
Juan Rivera ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Mexican Women ◽  
Dietary Intakes

Modulation of Kupffer cell membrane phospholipid function by n-3 polyunsaturated fatty acids

1989 ◽  
Vol 46 (5) ◽  
pp. 439-444 ◽  
Author(s):  
P.E. Bankey ◽  
T.R. Billiar ◽  
W.Y. Wang ◽  
A. Carlson ◽  
R.T. Holman ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Cell Membrane ◽  
Polyunsaturated Fatty Acids ◽  
Kupffer Cell ◽  
Membrane Phospholipid

The Associations of Dietary Intake of Polyunsaturated Fatty Acids With Diabetic Retinopathy in Well-Controlled Diabetes

2015 ◽  
Vol 56 (12) ◽  
pp. 7473 ◽  
Author(s):  
Mariko Sasaki ◽  
Ryo Kawasaki ◽  
Sophie Rogers ◽  
Ryan Eyn Kidd Man ◽  
Katsumasa Itakura ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Diabetic Retinopathy ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake

scholarly journals Positive Associations of Dietary Marine Omega-3 Polyunsaturated Fatty Acids with Lung Function: A Meta-analysis (P18-087-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Bonnie Patchen ◽  
Jiayi Xu ◽  
R Graham Barr ◽  
Ester van Eekelen ◽  
Josee Dupuis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lung Function ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Fish Intake ◽  
Omega 3 ◽  
Black And White ◽  
Former Smokers

Abstract Objectives Our previous study found positive associations between plasma levels of the omega-3 polyunsaturated fatty acids (n-3 PUFAs), specifically docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA), and lung function, especially in current smokers. Given that plasma n-3 PUFA concentrations are driven by dietary intake, we extended our prior findings to a larger sample by studying dietary n-3 PUFAs, including DHA, DPA, eicosapentanoic acid (EPA), and alpha-linolenic acid (ALA), and fish intake. Methods Nine cohorts from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (N = 37,077 black and white participants) contributed dietary intake and lung function data. In each cohort and each ancestry, separately, associations of dietary n-3 PUFA/fish intake with lung function were estimated in linear regression models. Models were extended to test for n-3 PUFA/fish × smoking status interaction. Fixed-effects meta-analysis was used to generate summarized effect estimates across the cohorts and ancestries. Results Dietary DPA, DHA, EPA, and fish intake were positively associated with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). ALA had little to no association with these lung function parameters. Associations were similar for black and white participants, and consistent in direction and magnitude across most cohorts. For all participants, 1 standard deviation (SD) higher intake of DPA (∼30 mg/d), DHA (∼200 mg/d), and EPA (∼150 mg/d) were associated with 12–16 mL higher FEV1 and 10–15 mL higher FVC. The effect estimates for fish were in the same direction but smaller in magnitude. Smoking modified the associations of DHA and EPA with FEV1 and FVC; 1 SD higher intake of DHA and EPA were associated with 28–32 mL higher FEV1 and 24–25 mL higher FVC in current smokers, 17–21 mL higher FEV1 and 7–12 mL higher FVC in former smokers, and little to no association in never smokers. Conclusions Dietary DHA, DPA, and EPA, but not ALA, are positively associated with FEV1 and FVC, corroborating our previous findings for plasma n-3 PUFAs. This large cross-sectional meta-analysis shows that diets rich in marine n-3 PUFAs are associated with higher lung function, especially for current and former smokers. Funding Sources National Institutes of Health, NHLBI and NIDDK.

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