IgE Antibodies to Malassezia furfur, M. sympodialis and Pityrosporum orbiculare in Patients with Atopic Dermatitis, Seborrheic Eczema or Pityriasis Versicolor, and Identification of Respective Allergens

Background: Pityriasis versicolor is a superficial fungal infection caused by the polymorphous endogenous yeast Malassezia furfur. Infection typically occurs on the trunk and proximal upper extremities and is characterized by distinctive scaly, coalescent hyperpigmented and/or hypopigmented to erythematous patches. Tinea versicolor is a superficial chronically recurring fungal infection of the stratum corneum, characterized by scaly, hypo and hyperpigmented irregular macules, usually located on the trunk and proximal extremities caused by pityrosporum orbiculare.Methods: 100 patients of untreated tinea versicolor who attended the outpatient department were selected at random irrespective of their age, socioeconomic status, occupation. A detailed history was taken, regarding the age, sex, religion, occupation, socioeconomic status, residence, duration and course of the disease, site of distribution of lesion and any other associated cutaneous and systemic diseases.Results: The majority patients i.e. 27 (27%) were students and followed by the unskilled workers who comprised 20% of patients. The incidence is quite low in business and official class 3% and 11% respectively. Conclusions: The duration of the disease in 93% of patients was less than 10 years and in 7% the duration was more than 10 years.

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PROFIL PITIRIASIS VERSIKOLOR DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R.D KANDOU MANADO PERIODE JANUARI – DESEMBER 2012

e-CliniC ◽

10.35790/ecl.3.1.2015.6761 ◽

2015 ◽

Vol 3 (1) ◽

Author(s):

Silvia Nathalia ◽

Nurdjannah J. Niode ◽

Herry E. J. Pandaleke

Keyword(s):

Civil Servant ◽

Pityriasis Versicolor ◽

The Body ◽

Malassezia Furfur ◽

Age Group ◽

Epidermal Layer ◽

Lesion Location ◽

The Face ◽

Pityrosporum Orbiculare ◽

Anti Fungal

Abstract: Pityriasis versicolor is a superficial fungal infection of the epidermal layer caused by Malassezia furfur or Pityrosporum orbiculare. This infection is chronic, mild, and usually without inflammation. Pityriasis versicolor infects the face, neck, torso, upper arms, underarms, thighs, andgroin. Skin disorders are very superficial and pityriasis versicolor is most commonly found in the body. The disorder is seen a spatches of colorful irregular shape to a regular, well defined to diffuse. The disorder is usually asymptomatic so that sometimes people do not know they have been infected. This study aims to determine profil of pityriasis versicolor at dermatovenereology clinic of Prof. Dr. R. D. Kandou General Hospital Manado periods January- December 2012. This retrospective descriptivestudy is based on the number of cases, gender, age, occupation, color of lesion, location of lesion, and the type of treatment. The results of this study showed that out of the 50 pityriasis versicolor cases (1.24%), male as the most infected gender (74%), along with the age group 25-44years (28%), the most job is civil servant (24%), and with hypopigmented lesions as the most types found (78%). The most frequent location of lesion is a combination of several places such as the face, body and extremities (60%), and the most used treatment is a combination therapy of oral and topical anti fungal (72%).Keywords: pityriasis versicolorAbstrak: Pitiriasis versikolor adalah infeksi jamur superfisial pada lapisan tanduk kulit yang disebabkan oleh Malassezia furfur atau Pityrosporum orbiculare. Infeksi ini bersifat menahun, ringan, dan biasanya tanpa peradangan. Pitiriasis versikolor mengenai muka, leher, badan, lengan atas, ketiak, paha, dan lipat paha. Kelainan kulit pitiriasis versikolor sangat superfisial dan ditemukan terutama di badan. Kelainan ini terlihat sebagai bercak-bercak berwarna-warni bentuk tidak teratur sampai teratur, batas jelas sampai difus. Kelainan biasanya asimptomatik sehingga adakalanya penderita tidak mengetahui bahwa ia berpenyakit tersebut. Tujuan penelitian ini adalah untuk mengetahui profil pitiriasis versikolor di Poliklinik Kulit dan Kelamin RSUP Prof. DR. R.D. Kandou Manado periode Januari-Desember 2012. Penelitian ini merupakan penelitian deskriptif retrospektif berdasarkan jumlah kasus, jenis kelamin, umur, pekerjaan, warna lesi, lokasi lesi, dan jenis pengobatan. Hasil penelitian ini menunjukkan bahwa dari 50 kasus pitiriasis versikolor ( 1,24% ) terbanyak adalah jenis kelamin laki-laki (74%), kelompok umur 25-44 tahun (28%), pekerjaan yang terbanyak adalah PNS (24%), jenis lesi paling banyak lesi hipopigmentasi (78%), lokasi lesi paling sering yaitu kombinasi yang terdapat dibeberapa tempat seperti wajah, badan dan ekstremitas ( 60%), dan pengobatan yang paling banyak adalah terapi kombinasi antijamur oral dan antijamur topikal (72%).Kata kunci: pitiriasis versikolor

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Head and Neck Atopic Dermatitis and Malassezia-furfur-Specific IgE Antibodies

Dermatology ◽

10.1159/000086438 ◽

2005 ◽

Vol 211 (2) ◽

pp. 107-113 ◽

Cited By ~ 32

Author(s):

O. Bayrou ◽

C. Pecquet ◽

A. Flahault ◽

C. Artigou ◽

N. Abuaf ◽

...

Keyword(s):

Atopic Dermatitis ◽

Head And Neck ◽

Specific Ige ◽

Malassezia Furfur ◽

Ige Antibodies ◽

Specific Ige Antibodies

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IgE antibodies to protein and mannan antigens of pityrosporum ovale in atopic dermatitis patients

Clinical & Experimental Allergy ◽

10.1046/j.1365-2222.1997.d01-425.x ◽

1997 ◽

Vol 27 (1) ◽

pp. 87-95 ◽

Cited By ~ 17

Author(s):

P. LINTU ◽

J. SAVOLAINEN ◽

K. KALIMO

Keyword(s):

Atopic Dermatitis ◽

Ige Antibodies ◽

Pityrosporum Ovale

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Anti-Malassezia furfur activity of essential oils against causal agent of Pityriasis versicolor disease

African Journal of Pharmacy and Pharmacology ◽

10.5897/ajpp12.097 ◽

2012 ◽

Vol 6 (13) ◽

Author(s):

Richa Sharma

Keyword(s):

Essential Oils ◽

Pityriasis Versicolor ◽

Causal Agent ◽

Malassezia Furfur

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Treatment of Atopic Dermatitis by Allergen-Antibody Complexes: Long-Term Clinical Results and Evolution of IgE Antibodies

Dermatology ◽

10.1159/000247565 ◽

1992 ◽

Vol 184 (4) ◽

pp. 271-274 ◽

Cited By ~ 8

Author(s):

B.P. Leroy ◽

J.-M. Lachapelle ◽

M. Jacquemin ◽

J.-M. Saint-Remy

Keyword(s):

Atopic Dermatitis ◽

Clinical Results ◽

Ige Antibodies

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CLINICAL SIGNIFICANCE OF DETERMINATION OF IGE ANTIBODIES TO STAPHYLOCOCCUS AUREUS AND MALASSEZIA SPECIES IN SERUM OF CHILDREN WITH ATOPIC DERMATITIS

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) ◽

10.21508/1027-4065-2018-63-4-84-88 ◽

2018 ◽

Vol 63 (4) ◽

pp. 84-88

Author(s):

T. S. Okuneva ◽

M. V. Kushnareva ◽

A. N. Pampura ◽

E. E. Varlamov ◽

N. G. Konyukova

Keyword(s):

Staphylococcus Aureus ◽

Atopic Dermatitis ◽

Clinical Significance ◽

Specific Ige ◽

Frequency Of Occurrence ◽

Ige Antibodies ◽

Malassezia Species ◽

Specific Ige Antibodies ◽

Malassezia Spp

We studied the frequency of occurrence and concentration of allergen-specific IgE antibodies (asIgE) to enterotoxins A, B, C and TSST-1 of Staphylococcus aureus and Malassezia spp. in the serum of children with atopic dermatitis in the acute period of the disease. The determination of asIgE levels was performed in 84 children aged from 5 months to 17 years using the immunochemiluminescent method on the UniCAP 100 analyzer (Phadia, Sweden). The level of asIgE was evaluated on a scale of 6 classes.The sensitization to S. aureus enterotoxins was detected in 29 children with аsIgE concentration from 0.35 to 25.8 kU/L (I–IV classes). In 16 children were observed 8 polysensitization options to S. aureus allergens. Combinations of asIgE to A + B and A + B + C enterotoxins were most common – in every fourth and fifth child,respectively. Sensitization to Malassezia spp. was observed in 41 children with concentration from 0.38 to 98.9 KU/L (I–V classes). Polysensitization to both S. aureus and Malassezia spp. allergens was observed in one of two children. A higher degree of sensitisation to Malassezia spp allergens has been established compared to S. aureus.Conclusion. To improve the specific diagnostics of atopic dermatitis, it is advisable to examine the serum for a complete panel of recombinant S. aureus enterotoxins in combination with the determination of asIgE to Malassezia spp.

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