Efficient Synthesis ofbis- andtris-Indolylalkanes Catalyzed by a Brønsted Acid–Surfactant Catalyst in Water

An efficient approach for the synthesis of chromene derivatives from vinyl o-quinone methides was established via a Brønsted acid catalyzed electrocyclization. By using this methodology, a series of structurally diversified chromenes was synthesized in a highly atom-economic and environmentally benign manner with generally good to excellent yields (up to 98% yield). This reaction will not only provide an efficient method for the construction of chromene scaffolds, but also enrich the research area of o-quinone methides.

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Brønsted acid cocatalysis in photocatalytic intramolecular coupling of tertiary amines: efficient synthesis of 2-arylindols

Organic & Biomolecular Chemistry ◽

10.1039/c6ob01239f ◽

2016 ◽

Vol 14 (31) ◽

pp. 7447-7450 ◽

Cited By ~ 13

Author(s):

Xiaoqian Yuan ◽

Xinxin Wu ◽

Shupeng Dong ◽

Guibing Wu ◽

Jinxing Ye

Keyword(s):

Visible Light ◽

Visible Light Irradiation ◽

Room Temperature ◽

Coupling Reaction ◽

Bronsted Acid ◽

Tertiary Amines ◽

Brønsted Acid ◽

Efficient Synthesis ◽

Unsaturated Ketones ◽

Brönsted Acid

We report herein a highly efficient intramolecular coupling reaction of tertiary amines and ketones (α,β-unsaturated ketones) by using a Brønsted acid as a cocatalyst, affording 2-arylindols in good to excellent yields (up to 92%) under visible light irradiation at room temperature.

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The first example of glucose-containing carbene Brønsted acid synthesis and catalysis: efficient synthesis of five substituted tetrahydropyridines

Tetrahedron ◽

10.1016/j.tet.2015.06.062 ◽

2015 ◽

Vol 71 (38) ◽

pp. 7070-7072 ◽

Cited By ~ 8

Author(s):

Qiu-ju Zhou ◽

Yu Wan ◽

Xiao-xiao Zhang ◽

Li-zhuo Zhang ◽

Huan Zou ◽

...

Keyword(s):

Acid Synthesis ◽

Bronsted Acid ◽

Brønsted Acid ◽

Efficient Synthesis ◽

Brönsted Acid

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Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

Chemical Communications ◽

10.1039/c3cc49063g ◽

2014 ◽

Vol 50 (17) ◽

pp. 2196-2198 ◽

Cited By ~ 20

Author(s):

Lin Qiu ◽

Xin Guo ◽

Chaoqun Ma ◽

Huang Qiu ◽

Shunying Liu ◽

...

Keyword(s):

Michael Addition ◽

Cascade Reactions ◽

Bronsted Acid ◽

Brønsted Acid ◽

Efficient Synthesis ◽

Mannich Reactions ◽

Cyclic Acetals ◽

Brönsted Acid

Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.

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Highly Efficient Synthesis of Tri- and Tetrasubstituted Conjugated Enynes from Brønsted Acid Catalyzed Alkoxylation of 1-Cyclopropylprop-2-yn-1-ols with Alcohols

The Journal of Organic Chemistry ◽

10.1021/jo9008244 ◽

2009 ◽

Vol 74 (16) ◽

pp. 5887-5893 ◽

Cited By ~ 28

Author(s):

Srinivasa Reddy Mothe ◽

Philip Wai Hong Chan

Keyword(s):

Bronsted Acid ◽

Brønsted Acid ◽

Efficient Synthesis ◽

Highly Efficient ◽

Brönsted Acid ◽

Conjugated Enynes ◽

Acid Catalyzed

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Efficient synthesis of pyrrolo[1,2-a]quinoxalines catalyzed by a Brønsted acid through cleavage of C–C bonds

Organic & Biomolecular Chemistry ◽

10.1039/c6ob01401a ◽

2016 ◽

Vol 14 (36) ◽

pp. 8529-8535 ◽

Cited By ~ 19

Author(s):

Caixia Xie ◽

Lei Feng ◽

Wanli Li ◽

Xiaojun Ma ◽

Xinkun Ma ◽

...

Keyword(s):

Direct Synthesis ◽

Domino Reaction ◽

Bronsted Acid ◽

Brønsted Acid ◽

Efficient Synthesis ◽

One Pot ◽

Keto Esters ◽

Brönsted Acid

An efficient and convenient one-pot domino reaction for the direct synthesis of pyrrolo[1,2-a]quinoxalines has been developed. β-Diketones and β-keto esters are well tolerated to give the corresponding products in moderate to excellent yields.

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