A comparative study on the interaction with calf thymus DNA of a Ni(II) complex of the anticancer drug adriamycin and a Ni(II) complex of sodium 1,4-dihydroxy-9,10-anthraquinone-2-sulphonate

2012 ◽  
Vol 65 (4) ◽  
pp. 705-721 ◽  
Author(s):  
Partha Sarathi Guin ◽  
P.C. Mandal ◽  
Saurabh Das
Keyword(s):  
Comparative Study ◽  
Anticancer Drug ◽  
Calf Thymus Dna ◽  
Calf Thymus

Effects of the anticancer drug cis-diamminedichloroplatinum(II) on the activities of calf thymus DNA polymerase .epsilon.

Biochemistry ◽  
1993 ◽  
Vol 32 (3) ◽  
pp. 841-848 ◽  
Author(s):  
Lin Huang ◽  
John J. Turchi ◽  
Alan F. Wahl ◽  
Robert A. Bambara
Keyword(s):  
Dna Polymerase ◽  
Anticancer Drug ◽  
Calf Thymus Dna ◽  
Dna Polymerase Epsilon ◽  
Calf Thymus ◽  
Polymerase Epsilon

Immobilization of methotrexate anticancer drug onto the graphene surface and interaction with calf thymus DNA and 4T1 cancer cells

2018 ◽  
Vol 119 ◽  
pp. 1-9 ◽  
Author(s):  
Reza Karimi Shervedani ◽  
Hadiseh Mirhosseini ◽  
Marzieh Samiei Foroushani ◽  
Mostafa Torabi ◽  
Fatemeh Rahnemaye Rahsepar ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Anticancer Drug ◽  
Calf Thymus Dna ◽  
Graphene Surface ◽  
Calf Thymus

scholarly journals Exploration of Electrochemical Intermediates of the Anticancer Drug Doxorubicin Hydrochloride Using Cyclic Voltammetry and Simulation Studies with an Evaluation for Its Interaction with DNA

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Partha Sarathi Guin ◽  
Saurabh Das
Keyword(s):  
Cyclic Voltammetry ◽  
Anticancer Drug ◽  
Dna Interaction ◽  
Calf Thymus Dna ◽  
Potential Range ◽  
Spectroscopic Techniques ◽  
Doxorubicin Hydrochloride ◽  
Cathodic Peak ◽  
Peak Current ◽  
Calf Thymus

Electrochemical behavior of the anticancer drug doxorubicin hydrochloride was studied using cyclic voltammetry in aqueous medium using Hepes buffer (pH~7.4). At this pH, doxorubicin hydrochloride undergoes a reversible two-electron reduction withE1/2value −665±5 mV (versus Ag/AgCl, saturated KCl). Depending on scan rates, processes were either quasireversible (at low scan rates) or near perfect reversible (at high scan rates). This difference in behavior of doxorubicin hydrochloride with scan rate studied over the same potential range speaks of differences in electron transfer processes in doxorubicin hydrochloride. Attempt was made to identify and understand the species involved using simulation. The information obtained was used to study the interaction of doxorubicin hydrochloride with calf thymus DNA. Cathodic peak current gradually decreased as more calf thymus DNA was added. The decrease in cathodic peak current was used to estimate the interaction of the drug with calf thymus DNA. Nonlinear curve fit analysis was applied to evaluate the intrinsic binding constant and site size of interaction that was compared with previous results on doxorubicin hydrochloride-DNA interaction monitored by cyclic voltammetry or spectroscopic techniques.

Interaction Studies of Anticancer Drug Lomustine with Calf Thymus DNA using Surface Enhanced Raman Spectroscopy

MAPAN ◽  
2013 ◽  
Vol 28 (4) ◽  
pp. 273-277 ◽  
Author(s):  
Ranjana Mehrotra ◽  
Deepak K. Jangir ◽  
Shweta Agarwal ◽  
Bhumika Ray ◽  
Parul Singh ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Anticancer Drug ◽  
Surface Enhanced Raman Spectroscopy ◽  
Calf Thymus Dna ◽  
Interaction Studies ◽  
Calf Thymus ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Binding Interaction of Cationic Phenazinium Dyes with Calf Thymus DNA: A Comparative Study

2008 ◽  
Vol 112 (30) ◽  
pp. 9243-9249 ◽  
Author(s):  
Deboleena Sarkar ◽  
Paramita Das ◽  
Soumen Basak ◽  
Nitin Chattopadhyay
Keyword(s):  
Comparative Study ◽  
Calf Thymus Dna ◽  
Binding Interaction ◽  
Calf Thymus
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