INHALATION OF DIESEL EXHAUST FOR THREE MONTHS AFFECTS MAJOR CYTOKINE EXPRESSION AND INDUCES BRONCHUS-ASSOCIATED LYMPHOID TISSUE FORMATION IN MURINE LUNGS

2003 ◽  
Vol 29 (8) ◽  
pp. 607-622 ◽  
Author(s):  
Kumiko Hiramatsu ◽  
Arata Azuma ◽  
Shoji Kudoh ◽  
Masashi Desaki ◽  
Hajime Takizawa ◽  
...  
Keyword(s):  
Diesel Exhaust ◽  
Lymphoid Tissue ◽  
Cytokine Expression ◽  
Tissue Formation

scholarly journals Diesel Exhaust Particles Enhance Antigen-induced Airway Inflammation and Local Cytokine Expression in Mice

1997 ◽  
Vol 156 (1) ◽  
pp. 36-42 ◽  
Author(s):  
HIROHISA TAKANO ◽  
TOSHIKAZU YOSHIKAWA ◽  
TAKAMICHI ICHINOSE ◽  
YUICHI MIYABARA ◽  
KOICHI IMAOKA ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Diesel Exhaust ◽  
Cytokine Expression ◽  
Diesel Exhaust Particles ◽  
Exhaust Particles ◽  
Local Cytokine

scholarly journals Nfil3 is required for the development of all innate lymphoid cell subsets

2014 ◽  
Vol 211 (9) ◽  
pp. 1733-1740 ◽  
Author(s):  
Cyril Seillet ◽  
Lucille C. Rankin ◽  
Joanna R. Groom ◽  
Lisa A. Mielke ◽  
Julie Tellier ◽  
...  
Keyword(s):  
Lymphoid Cell ◽  
Lymphoid Tissue ◽  
Nk Cell ◽  
Cell Development ◽  
Tissue Formation ◽  
Infectious Agents ◽  
Immune Protection ◽  
Innate Lymphoid Cell ◽  
Adaptive Immune ◽  
Genetic Deletion

Innate lymphoid cell (ILC) populations protect against infection and are essential for lymphoid tissue formation and tissue remodeling after damage. Nfil3 is implicated in the function of adaptive immune lineages and NK cell development, but it is not yet known if Nfil3 regulates other innate lymphoid lineages. Here, we identify that Nfil3 is essential for the development of Peyer’s patches and ILC2 and ILC3 subsets. Loss of Nfil3 selectively reduced Peyer’s patch formation and was accompanied by impaired recruitment and distribution of lymphocytes within the patches. ILC subsets exhibited high Nfil3 expression and genetic deletion of Nfil3 severely compromised the development of all subsets. Subsequently, Nfil3−/− mice were highly susceptible to disease when challenged with inflammatory or infectious agents. Thus, we demonstrate that Nfil3 is a key regulator of the development of ILC subsets essential for immune protection in the lung and gut.

scholarly journals Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice

2005 ◽  
Vol 79 (10) ◽  
pp. 595-599 ◽  
Author(s):  
Ken-ichiro Inoue ◽  
Hirohisa Takano ◽  
Rie Yanagisawa ◽  
Takamichi Ichinose ◽  
Akinori Shimada ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Diesel Exhaust ◽  
Cytokine Expression ◽  
Diesel Exhaust Particles ◽  
Pulmonary Exposure ◽  
Exhaust Particles

scholarly journals Stromal cells and B cells orchestrate ectopic lymphoid tissue formation in nasal polyps

Allergy ◽  
2020 ◽  
Author(s):  
Zhe‐Zheng Wang ◽  
Jia Song ◽  
Hai Wang ◽  
Jing‐Xian Li ◽  
Qiao Xiao ◽  
...  
Keyword(s):  
B Cells ◽  
Stromal Cells ◽  
Lymphoid Tissue ◽  
Nasal Polyps ◽  
Tissue Formation

scholarly journals Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation

Immunity ◽  
2016 ◽  
Vol 45 (6) ◽  
pp. 1299-1310 ◽  
Author(s):  
Etsushi Kuroda ◽  
Koji Ozasa ◽  
Burcu Temizoz ◽  
Keiichi Ohata ◽  
Christine X. Koo ◽  
...  
Keyword(s):  
Alveolar Macrophage ◽  
Lymphoid Tissue ◽  
Fine Particles ◽  
Tissue Formation ◽  
Interleukin 1Α
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