Cognitive outcome in children and young adults who sustained severe and moderate traumatic brain injury 10 years earlier

Brain Injury ◽  
2009 ◽  
Vol 23 (11) ◽  
pp. 907-914 ◽  
Author(s):  
Göran Horneman ◽  
Ingrid Emanuelson
Keyword(s):  
Traumatic Brain Injury ◽  
Young Adults ◽  
Brain Injury ◽  
Cognitive Outcome ◽  
Moderate Traumatic Brain Injury ◽  
Children And Young Adults

Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study

The Lancet ◽  
2009 ◽  
Vol 373 (9669) ◽  
pp. 1105-1110 ◽  
Author(s):  
Jakob Christensen ◽  
Marianne G Pedersen ◽  
Carsten B Pedersen ◽  
Per Sidenius ◽  
Jørn Olsen ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Young Adults ◽  
Cohort Study ◽  
Brain Injury ◽  
Population Based ◽  
Children And Young Adults

Cognitive and neurobehavioral functioning after mild versus moderate traumatic brain injury in older adults

2001 ◽  
Vol 7 (3) ◽  
pp. 373-383 ◽  
Author(s):  
FELICIA C. GOLDSTEIN ◽  
HARVEY S. LEVIN ◽  
WILLIAM P. GOLDMAN ◽  
ALLISON N. CLARK ◽  
TRACY KENEHAN ALTONEN
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Outcome ◽  
Cognitive Measures ◽  
Post Injury ◽  
Mild Tbi ◽  
Moderate Traumatic Brain Injury ◽  
Comparable Control ◽  
Neurobehavioral Outcomes

This study evaluated the early cognitive and neurobehavioral outcomes of older adults with mild versus moderate traumatic brain injury (TBI). Thirty-five patients who were age 50 years and older and sustained mild or moderate TBI were prospectively recruited from acute care hospitals. Patients were administered cognitive and neurobehavioral measures up to 2 months post-injury. Demographically comparable control participants received the same measures. Patients and controls did not have previous histories of substance abuse, neuropsychiatric disturbance, dementia, or neurologic illness. Moderate TBI patients performed significantly poorer than mild TBI patients and controls on most cognitive measures, whereas the mild patients performed comparably to controls. In contrast, both mild and moderate patients exhibited significantly greater depression and anxiety/somatic concern than controls. The results indicate that the classification of TBI as mild versus moderate is prognostically meaningful as applied to older adults. The findings extend previous investigations in young adults by demonstrating a relatively good cognitive outcome on objective measures, but subjective complaints after a single, uncomplicated mild TBI in older persons. (JINS, 2001, 7, 373–383.)

scholarly journals Overview of admissions for traumatic brain injury in Brazil in the last 5 years

2021 ◽  
Author(s):  
Caio Felipe Thomazin Panicio ◽  
Ana Beatriz Tomiyoshi Koyama ◽  
André Felipe Cortez Mendes ◽  
Andressa Algazal ◽  
Angelo Luis Tonon Santana ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Information System ◽  
Young Adults ◽  
Brain Injury ◽  
Data Collection ◽  
Traffic Accidents ◽  
Descriptive Study ◽  
Age Group ◽  
Progressive Decline ◽  
Children And Young Adults

Introduction: Head trauma (TBI) is the main cause of morbidity and mortality in children and young adults. The most frequent causes involve: traffic accidents, falls and aggressions. The objective is to assess the epidemiology of TBI in Brazil according to age, sex and deaths over a 5-year period. Methods: Ecological and descriptive study. The data collection for this study was based on results obtained through the Health Information (TABNET) and the SUS Hospital Information System (SIH / SUS) in the period from 2016 to 2020. Results: There were 515,235 admissions due to TBI, with a higher prevalence in the Southeast, with 211,972 cases (41.14%), followed by the Northeast, with 136,705 (26.53%). There was a predominance of males, with 391,991 (76.08%). The age group most affected was between 20 and 29 years and 30 to 39 years, with 83,581 (16.22%) and 75,312 (14.61%), respectively. From 2016 to 2020 there was a decrease of 7.33% in the number of cases, 2016 being the most prevalent year, with 106,497, and 2020 the least incident year, with 98,690 hospitalizations. Of the 515,235 cases, 9.59% died, with its peak in 2016, with 10,364 deaths. Conclusion: The profile was given by a male figure between 20 and 29 years old, from the Southeast region. Taking into account the progressive decline in incidence, it can be deduced that orientations are being made. However, the numbers are still high, requiring measures to raise awareness about risks and prevention, since, most cases can be preventable.

scholarly journals The effect of serum D-dimer levels on the cognitive outcome of patients with moderate traumatic brain injury

2021 ◽  
Vol 36 (1) ◽  
Author(s):  
Mohammed F.A Ali ◽  
Ahmed M.F Ghoul ◽  
Mohamed I Refaat
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Statistical Significance ◽  
Elevated Serum ◽  
Serum Levels ◽  
Cognitive Outcome ◽  
Treatment Protocols ◽  
Surgical Interventions ◽  
Moderate Traumatic Brain Injury ◽  
D Dimer

Abstract Background Cognitive impairment after traumatic brain injury (TBI) is a main source of morbidity for affected individuals, their family members, and their community. There are numerous serum biomarkers, which are elevated after TBI; one of these is D-dimer. Several studies have related that trauma-related coagulopathy, marked by elevated D-dimer levels, is associated with poor prognosis. Objective The aim of this study was to find if there is a correlation between elevated serum levels of D-dimer and impairment of final cognitive outcome in case suffering of Moderate TBI. Patients and method This is a prospective cohort study with a random sample of 87 patients suffering from moderate TBI. Serum level of D-dimer was requested for all cases after confirming the diagnosis of moderate TBI with post-traumatic GCS 9–12. Head trauma treatment protocols were followed according to each case diagnosis and then at the time of discharge cognitive outcome was assessed for all cases. Neurocognition was assessed by Montreal cognitive assessment-Basic (MoCA-B). Results Eighty-seven cases were included in this trial with a mean age 28 years. 48.3% of cases were treated conservatively while the remaining 51.7% needed surgical interventions for different pathologies. Seventy-five cases had elevated levels of serum D-dimer (86.2%) whereas only 12 cases have within normal levels (13.8%). A twofold increase in the serum D-dimer level was found in 41% of cases, while 34.5% of cases had three- to sixfold increases, and 10% of cases had more than sixfold increase. The mean MoCA-B score was 24 points (range 13–27). Correlating the D-dimer levels statistically with the MoCA scores, age, admission and discharge GCS, and durations of hospital stay did not show any statistical significance with any of these variables. Conclusion The role played by D-dimer in the pathophysiology of cognitive deficits and its correlation with post moderate TBI cognitive outcome was not proven.

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