Uterine fibroid embolization can still be improved: observations on post-procedure magnetic resonance imaging

2005 ◽  
Vol 46 (5) ◽  
pp. 547-553 ◽  
Author(s):  
E. J. Dorenberg ◽  
Z. Novakovic ◽  
H.-J. Smith ◽  
G. Hafsahl ◽  
J. Å. Jakobsen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Resonance Imaging ◽  
Post Contrast ◽  
Uterine Fibroid Embolization ◽  
Uterine Arteries ◽  
Uterine Volume

Purpose: To evaluate the efficacy and completeness of uterine fibroid embolization (UFE) measured by changes in volume and signal intensity at magnetic resonance imaging (MRI), and to compare with clinical outcome. Material and Methods: 40 women with symptomatic uterine fibroids underwent bilateral uterine artery embolization. At MRI studies, including post-contrast sequences before and repeatedly after treatment, the uterus and dominant fibroids were evaluated for volume, location, and contrast enhancement. Prior to treatment, all myomas showed significant contrast enhancement. The mean uterine volume was 929 ml. Clinical examinations with emphasis on menorrhagia, pelvic pain, and urinary dysfunction were performed before and 6 and 12 months after treatment. Results: UFE was bilaterally successful in 38 patients. After UFE, MRI showed no enhancement of myomas in 30 patients. In 8 patients, post-procedural MRI revealed partially remaining vascularization of fibroids despite angiographically complete embolization of the uterine arteries. On average, uterine volume decreased by 46.2% at 12 months. There was significant improvement of symptoms in the majority of patients, but slightly less improvement in patients with partially remaining vascularization of myomas. Conclusion: UFE causes significant volume reduction of myomas and clinical improvement. MRI can reveal remaining vascularization in myomas despite angiographically complete embolization of uterine arteries.

scholarly journals Correlative Magnetic Resonance Imaging and Histopathology in Small Ruminant Listeria Rhombencephalitis

2020 ◽  
Vol 11 ◽  
Author(s):  
Christina Precht ◽  
Peter Vermathen ◽  
Diana Henke ◽  
Anne Staudacher ◽  
Josiane Lauper ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Signal Intensity ◽  
Small Ruminants ◽  
Large Animal ◽  
Resonance Imaging ◽  
Post Contrast ◽  
Mri Features ◽  
Inflammatory Infiltrates

Background: Listeria rhombencephalitis, infection of the brainstem with Listeria monocytogenes, occurs mainly in humans and farmed ruminants and is associated with high fatality rates. Small ruminants (goats and sheep) are a large animal model due to neuropathological similarities. The purpose of this study was to define magnetic resonance imaging (MRI) features of listeria rhombencephalitis in naturally infected small ruminants and correlate them with histopathology. Secondly, the purpose of this study was to compare the results with MRI findings reported in humans.Methods: Twenty small ruminants (13 sheep and 7 goats) with listeria rhombencephalitis were prospectively enrolled and underwent in vivo MRI of the brain, including T2-weighted, fluid attenuation inversion recovery, and T1-weighted sequences pre- and post-contrast administration and postmortem histopathology. In MRI, lesions were characterized by location, extent, border definition, signal intensity, and contrast enhancement. In histopathology, the location, cell type, severity, and chronicity of inflammatory infiltrates and signs of vascular damage were recorded. In addition, histopathologic slides were matched to MRIs, and histopathologic and MRI features were compared.Results: Asymmetric T2-hyperintense lesions in the brainstem were observed in all animals and corresponded to the location and pattern of inflammatory infiltrates in histopathology. Contrast enhancement in the brainstem was observed in 10 animals and was associated with vessel wall damage and perivascular fibrin accumulation in 8 of 10 animals. MRI underestimated the extension into rostral brain parts and the involvement of trigeminal ganglia and meninges.Conclusion: Asymmetric T2-hyperintense lesions in the brainstem with or without contrast enhancement can be established as criteria for the diagnosis of listeria rhombencephalitis in small ruminants. Brainstem lesions were similar to human listeria rhombencephalitis in terms of signal intensity and location. Different from humans, contrast enhancement was a rare finding, and abscessation was not observed.

scholarly journals Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism

2018 ◽  
Vol 7 (3) ◽  
pp. 413-424 ◽  
Author(s):  
Marianne Aa Grytaas ◽  
Kjersti Sellevåg ◽  
Hrafnkell B Thordarson ◽  
Eystein S Husebye ◽  
Kristian Løvås ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Primary Aldosteronism ◽  
T1 Mapping ◽  
Newly Diagnosed ◽  
Resonance Imaging ◽  
Post Contrast ◽  
Lv Mass

Background Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. Cardiac magnetic resonance imaging (CMR) contrast enhancement and novel sensitive T1 mapping to estimate increased extracellular volume (ECV) are available to measure the extent of fibrosis. Objectives To assess LV mass and fibrosis before and after treatment of PA using CMR with contrast enhancement and T1 mapping. Methods Fifteen patients with newly diagnosed PA (PA1) and 24 age- and sex-matched healthy subjects (HS) were studied by CMR with contrast enhancement. Repeated imaging with a new scanner with T1 mapping was performed in 14 of the PA1 and 20 of the HS median 18 months after specific PA treatment and in additional 16 newly diagnosed PA patients (PA2). Results PA1 had higher baseline LV mass index than HS (69 (53–91) vs 51 (40–72) g/m2; P < 0.001), which decreased significantly after treatment (58 (40–86) g/m2; P < 0.001 vs baseline), more with adrenalectomy (n = 8; −9 g/m2; P = 0.003) than with medical treatment (n = 6; −5 g/m2; P = 0.075). No baseline difference was found in contrast enhancement between PA1 and HS. T1 mapping showed no increase in ECV as a myocardial fibrosis marker in PA. Moreover, ECV was lower in the untreated PA2 than HS 10 min post-contrast, and in both PA groups compared with HS 20 min post-contrast. Conclusion Specific treatment rapidly reduced LV mass in PA. Increased myocardial fibrosis was not found and may not represent a common clinical problem.

Magnetic resonance imaging changes following natalizumab discontinuation in multiple sclerosis patients with progressive multifocal leukoencephalopathy

2018 ◽  
Vol 24 (14) ◽  
pp. 1902-1908 ◽  
Author(s):  
Jérôme Hodel ◽  
Blanche Bapst ◽  
Olivier Outteryck ◽  
Sébastien Verclytte ◽  
Vincent Deramecourt ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Multifocal Leukoencephalopathy ◽  
Contrast Enhancement ◽  
Mass Effect ◽  
Resonance Imaging ◽  
Post Contrast ◽  
Fluid Attenuated Inversion Recovery ◽  
Multiple Sclerosis Patients ◽  
Mri Changes

Background: Detecting early progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome (PML-IRIS) is clinically relevant. Objective: Evaluating magnetic resonance imaging (MRI) changes following natalizumab (NTZ) discontinuation and preceding PML-IRIS. Methods: MRIs (including diffusion-weighted imaging (DWI), T2-weighted fluid-attenuated inversion recovery (T2-FLAIR), post-contrast T1-weighted sequences) were performed every week following PML diagnosis in 11 consecutive NTZ-PML patients. PML expansion, punctate lesions, contrast-enhancement, and mass-effect/edema were evaluated on each MRI sequence, following NTZ discontinuation. Results: PML-IRIS occurred from 26 to 89 days after NTZ discontinuation. MRI changes prior to early PML-IRIS appeared significantly more pronounced using DWI compared to T2-FLAIR imaging ( p < 0.003). Two DWI features (marked PML expansion, punctate lesions) systematically preceded contrast-enhancement. Conclusion: Subtle changes may occur on DWI preceding contrast-enhancement.

Predictive value of magnetic resonance imaging signal and contrast-enhancement characteristics on post-embolization volume reduction of uterine fibroids

2006 ◽  
Vol 47 (4) ◽  
pp. 427-435 ◽  
Author(s):  
M. Harman ◽  
Ş. ZeteroĞlu ◽  
H. Arslan ◽  
M. Şengül ◽  
Ö. Etlik
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Uterine Fibroids ◽  
Volume Reduction ◽  
High Signal ◽  
Resonance Imaging ◽  
Signal Characteristics ◽  
Before And After ◽  
Tumor Volume Reduction

Purpose: To assess the magnetic resonance imaging (MRI) signal and contrast-enhancement features of uterine fibroids before and after embolization, and to determine whether or not there are pre-embolization MRI characteristics that predict the volume reduction of fibroids. Material and Methods: Uterine fibroid embolization (UFE) was carried out in 28 fibroids of 20 patients, all of whom were symptomatic. The patients were prospectively evaluated with T1-weighted, T2-weighted, and gadolinium-enhanced T1 MRI sequences before and 6 months after embolization. The relationship between the characteristics of MRI signal and contrast-enhancement features of fibroids before the procedure and the change in size of the lesions after treatment was investigated. Results: Before embolization, the mean volume of fibroids was 123 cm3 (8–560 cm3). The decrease rate in fibroid volumes was 44.6% (range 7–70%) 6 months after embolization. Volume reduction was more prominent in fibroids that had a high signal intensity on T2-weighted images and a marked contrast enhancement on T1-weighted images ( P<0.001). However, the volume reduction was insufficient in fibroids with high signal characteristics on pre-contrast T1-weighted images ( P<0.001). Conclusion: MRI is an effective method for revealing size and signal changes of fibroids after embolization. MRI signal characteristics and the contrast-enhancement pattern of fibroids before embolization can predict tumor volume reduction after embolization.

Lipoma in olecranon bursa: A case report

2021 ◽  
Vol 3 ◽  
pp. 67-69
Author(s):  
Shalini Agarwal ◽  
Jyoti Siwach ◽  
Ramneet Wadi ◽  
Nipun Gupta
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Local Anesthesia ◽  
Signal Intensity ◽  
Ultrasound Examination ◽  
Fat Cells ◽  
Resonance Imaging ◽  
Diffusion Weighted Images

We report a case of a 55-year-old male patient who presented with swelling over his right elbow of 5-year duration. An ultrasound examination revealed an echogenic mass within the olecranon bursa. On magnetic resonance imaging, the mass revealed the signal intensity of fat, and it was attached to the bursal lining by means of a pedicle. There was no restriction on diffusion-weighted images and no significant contrast enhancement. Excision was performed under local anesthesia. The excised specimen revealed mature fat cells on histopathology.

Magnetic Resonance Imaging of Brain Involvement in Dogs Using Paramagnetic Contrast Enhancement with Mn(II)-DCTA P

2016 ◽  
Vol 161 (5) ◽  
pp. 715-718
Author(s):  
W. Yu. Ussov ◽  
M. L. Belyanin ◽  
A. I. Bezlepkin ◽  
O. Yu. Borodin ◽  
E. E. Bobrikova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Enhancement ◽  
Resonance Imaging ◽  
Brain Involvement
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