scholarly journals The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen

Platelets ◽  
2021 ◽  
pp. 1-11
Author(s):  
Joy R Wright ◽  
Sarah Jones ◽  
Sasikumar Parvathy ◽  
Leonard K Kaczmarek ◽  
Ian Forsythe ◽  
...  
Keyword(s):  
K Channel ◽  
Voltage Gated ◽  
Α2β1 Integrin

Structural Influence of Hanatoxin Binding on the Carboxyl Terminus of S3 Segment in Voltage-Gated K + -Channel Kv2.1

2002 ◽  
Vol 8 (2) ◽  
pp. 79-85 ◽  
Author(s):  
P. T. Huang ◽  
T. Y. Chen ◽  
L. J. Tseng ◽  
K. L. Lou ◽  
H. H. Liou ◽  
...  
Keyword(s):  
Carboxyl Terminus ◽  
K Channel ◽  
Voltage Gated ◽  
S3 Segment ◽  
Structural Influence

TNF-α inhibits the CD3-mediated upregulation of voltage-gated K+ channel (Kv1.3) in human T cells

2010 ◽  
Vol 391 (1) ◽  
pp. 909-914 ◽  
Author(s):  
Bo Pang ◽  
Haifeng Zheng ◽  
Dong Hoon Shin ◽  
Kyeong Cheon Jung ◽  
Jae Hong Ko ◽  
...  
Keyword(s):  
T Cells ◽  
K Channel ◽  
Voltage Gated ◽  
Human T Cells ◽  
Tnf Α

Hanging Gondola Structure of the T1 Domain in a Voltage-Gated K+Channel†

Biochemistry ◽  
2000 ◽  
Vol 39 (34) ◽  
pp. 10347-10352 ◽  
Author(s):  
William R. Kobertz ◽  
Carole Williams ◽  
Christopher Miller
Keyword(s):  
K Channel ◽  
Voltage Gated ◽  
T1 Domain

scholarly journals Regulation of the Voltage Gated K+Channel Kv1.3by Recombinant Human Klotho Protein

2014 ◽  
Vol 39 (6) ◽  
pp. 609-622 ◽  
Author(s):  
Ahmad Almilaji ◽  
Sabina Honisch ◽  
Guilai Liu ◽  
Bernat Elvira ◽  
Sumant Singh Ajay ◽  
...  
Keyword(s):  
K Channel ◽  
Voltage Gated ◽  
Klotho Protein

Kv2.1: A Voltage-Gated K+ Channel Critical to Dynamic Control of Neuronal Excitability

2005 ◽  
Vol 26 (5) ◽  
pp. 743-752 ◽  
Author(s):  
Hiroaki Misonou ◽  
Durga P. Mohapatra ◽  
James S. Trimmer
Keyword(s):  
Neuronal Excitability ◽  
Dynamic Control ◽  
K Channel ◽  
Voltage Gated

scholarly journals Kv5, Kv6, Kv8, and Kv9 subunits: No simple silent bystanders

2016 ◽  
Vol 147 (2) ◽  
pp. 105-125 ◽  
Author(s):  
Elke Bocksteins
Keyword(s):  
Therapeutic Strategies ◽  
K Channel ◽  
Biophysical Properties ◽  
Tissue Specific ◽  
Voltage Gated ◽  
Novel Treatments ◽  
Novel Therapeutic Strategies ◽  
Different Tissues ◽  
Novel Therapeutic

Members of the electrically silent voltage-gated K+ (Kv) subfamilies (Kv5, Kv6, Kv8, and Kv9, collectively identified as electrically silent voltage-gated K+ channel [KvS] subunits) do not form functional homotetrameric channels but assemble with Kv2 subunits into heterotetrameric Kv2/KvS channels with unique biophysical properties. Unlike the ubiquitously expressed Kv2 subunits, KvS subunits show a more restricted expression. This raises the possibility that Kv2/KvS heterotetramers have tissue-specific functions, making them potential targets for the development of novel therapeutic strategies. Here, I provide an overview of the expression of KvS subunits in different tissues and discuss their proposed role in various physiological and pathophysiological processes. This overview demonstrates the importance of KvS subunits and Kv2/KvS heterotetramers in vivo and the importance of considering KvS subunits and Kv2/KvS heterotetramers in the development of novel treatments.

scholarly journals Developmental regulation of voltage-gated K+ channel and GABAA receptor expression in Bergmann glial cells

1994 ◽  
Vol 14 (5) ◽  
pp. 2503-2514 ◽  
Author(s):  
T Muller ◽  
JM Fritschy ◽  
J Grosche ◽  
GD Pratt ◽  
H Mohler ◽  
...  
Keyword(s):  
Gabaa Receptor ◽  
Glial Cells ◽  
Developmental Regulation ◽  
Receptor Expression ◽  
K Channel ◽  
Voltage Gated ◽  
Bergmann Glial Cells
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