Aiming at the problem of lower removal efficiency of ammonia nitrogen in the activated sludge process for wastewater treatment plant of Jilin Chemical Company, a few tests were studied such as filler selection, biological hydrolysis-acidification process, nitrobacteria cultivation, activated sludge process and biofilm process, the feasibility of simultaneous nitrification and denitrification(SND) was developed with biofilm treatment for chemical poor-biological wastewater. The results showed that: SND occurred in the aerobic section, effluent total basicity (TB) in biofilm process was 2mmol / L or more, and was higher than activated sludge process, while the effluent TB in activated sludge process was about 0.1mmol / L,and nitrate produced by activated sludge process was 30mg/L higher than that of biofilm process. Nitrogen removal efficiency using SJ-1-type filler made in Jiangsu Suzhou Purification Group Co., Ltd was 15.01% more than that using combined filler.