The use of commercially available games for a combined physical and cognitive challenge during exercise for individuals with Parkinson’s disease – a case series report

2018 ◽  
Vol 35 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Sujata Pradhan
2021 ◽  
pp. 1-5
Author(s):  
Jonathan R. Isaacson ◽  
Salima Brillman ◽  
Nisha Chhabria ◽  
Stuart H. Isaacson

Background: The diagnosis of Parkinson’s disease (PD) is primarily clinical, but in cases of diagnostic uncertainty, evaluation of nigrostriatal dopaminergic degeneration (NSDD) by imaging of the dopamine transporter using DaTscan with single-photon emission computed tomography (SPECT) brain imaging may be helpful. Objective/Methods: In the current paper, we describe clinical scenarios for which DaTscan imaging was used in a prospective case series of 201 consecutive patients in whom a movement disorder specialist ordered DaTscan imaging to clarify NSDD. We describe the impact of DaTscan results on changing or confirming pre-DaTscan clinical diagnosis and on post-DaTscan treatment changes. Results/Conclusion: DaTscan imaging can be useful in several clinical scenarios to determine if NSDD is present. These include in patients with early subtle symptoms, suboptimal response to levodopa, prominent action tremor, drug-induced parkinsonism, and in patients with lower extremity or other less common parkinsonism clinical presentations. We also found DaTscan imaging to be useful to determine underlying NSDD in patients with PD diagnosis for 3-5 years but without apparent clinical progression or development of motor fluctuations. Overall, in 201 consecutive patients with clinically questionable NSDD, DaTscan was abnormal in 58.7% of patients, normal in 37.8%, and inconclusive in 3.5%. DaTscan imaging changed clinical diagnosis in 39.8% of patients and led to medication therapy changes in 70.1% of patients.


2013 ◽  
Vol 271 (7) ◽  
pp. 1851-1856 ◽  
Author(s):  
B. K. Mukara ◽  
P. Munyarugamba ◽  
S. Dazert ◽  
J. Löhler

2012 ◽  
Vol 38 (10) ◽  
pp. 1435-1442 ◽  
Author(s):  
Mohamed I. Fayad ◽  
Paul J. Ashkenaz ◽  
Bradford R. Johnson

2018 ◽  
Vol 58 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Kimberly K. Monroe ◽  
Alexandra Rubin ◽  
Kerry P. Mychaliska ◽  
Maria Skoczylas ◽  
Heather L. Burrows

Lotus birth is the practice of leaving the umbilical cord uncut until separation occurs naturally. Our case series report describes delivery characteristics, neonatal clinical course, cord and placenta management, maternal reasons for a lotus birth, and desire for future lotus births. Between April 2014 and January 2017, six lotus births occurred. Mothers (four of the six) were contacted by phone after giving birth. A chart review was completed on each patient to evaluate if erythromycin ointment, hepatitis B vaccine, and vitamin K (intramuscular or oral) were administered, treatment of the placenta, maternal group B streptococcus status, postnatal infant fevers, infant hemoglobin or hematocrit levels, jaundice requiring phototherapy, and infant readmissions. Three of the six families decided to cut the cord before hospital discharge. No infections were noted. All contacted mothers would elect for a lotus birth again (4/6). One hepatitis B vaccine was given; all others declined perinatal immunization.


2016 ◽  
Vol 11 (4) ◽  
pp. 2899-2902 ◽  
Author(s):  
BO DENG ◽  
YI WANG ◽  
DONG XIE ◽  
SHAWN M. STODDARD ◽  
PING YANG

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