Serum vitamin D levels in relation to type-2 diabetes and prediabetes in adults: a systematic review and dose–response meta-analysis of epidemiologic studies

Author(s):  
Sobhan Mohammadi ◽  
Zahra Hajhashemy ◽  
Parvane Saneei
2020 ◽  
pp. 1-9 ◽  
Author(s):  
Yonggui Zhang ◽  
Xuefeng Jiang ◽  
Xiangjun Li ◽  
Mihnea-Alexandru Găman ◽  
Hamed Kord-Varkaneh ◽  
...  

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51171 ◽  
Author(s):  
Keitaro Yokoyama ◽  
Akio Nakashima ◽  
Mitsuyoshi Urashima ◽  
Hiroaki Suga ◽  
Takeshi Mimura ◽  
...  

Author(s):  
Jaitra Bhattacharya

Background: The 21st century has seen the rise of diabetes mellitus as one of the major metabolic issues as is vitamin D deficiency which has been found to be pandemic worldwide. The present study is an endeavor to study the status of serum vitamin D levels in relation to the glycemic and insulin resistance status in type 2 diabetes mellitus patients.Methods: The present is a cross-sectional study with a sample size of 100 type 2 diabetic subjects in the age group of 30-60 years. Serum vitamin D and Insulin levels were estimated using the ELISA technique. HbA1c levels were measured using immunoturbidimetric assays and plasma glucose levels were determined using glucose oxidase- peroxidase method.Results: The fasting plasma glucose, HbA1c and serum insulin levels were found to be significantly higher in those with vitamin D levels below the normal cut-off value of less than 30ng/ml (p value <0.01). Also, the insulin resistance calculated using HOMA-IR was found to be higher in those subjects having vitamin D deficiency or insufficiency.Conclusions: Hence, the study suggests that vitamin D deficiency contributes to further insulin resistance and poorer long-term diabetic control in type 2 diabetes mellitus subjects.


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