Interactions of ?Ultra-Low? Doses of Naltrexone and Morphine in Mature and Young Male and Female Rats

2004 ◽  
Vol 10 (2) ◽  
pp. 73-81 ◽  
Author(s):  
Scott Hamann ◽  
Hammad Malik ◽  
Jewell Sloan ◽  
Elzbieta Wala
2004 ◽  
Vol 10 (2) ◽  
pp. 73-81 ◽  
Author(s):  
Scott R. Hamann ◽  
Hammad Malik ◽  
Jewell W. Sloan ◽  
Elzbieta P. Wala

1978 ◽  
Vol 39 (3) ◽  
pp. 615-626 ◽  
Author(s):  
J. Bitman ◽  
Joan R. Weyant ◽  
D. L. Wood ◽  
T. R. Wrenn

1. The effect of vitamin B12 on growth was studied in young male and female rats fed on diets sufficient (+B12) or deficient (−B12) in vitamin B12 containing 30% of the dietary energy as fat, either maize oil (CO) or triundecanoin (TUD).2. Vitamin B12 deficiency severely depressed growth. After 6 weeks the weight gain of CO(−B12) rats was only 72% of that of CO(+B12) rats and the gain of TUD(−B12) rats was only 47% of TUD(+B12) rats.3. After fasting 24 or 96 h TUD-fed rats, both + B12 and −B12, had greater glycogen reserves and higher plasma glucose levels than CO-fed rats.4. It is concluded that vitamin B12 is required for the metabolism and utilization of both an odd-carbon-number medium-chain fat, TUD, and an even-C-number long-chain fat, CO, during growth in rats.


2000 ◽  
Vol 46 (5) ◽  
pp. 35-39
Author(s):  
L. I. Nadolnik ◽  
N. V. Emelyanov ◽  
I. P. Pasteur ◽  
V. V. Vinogradov

Main parameters of complex formation of corticosteroid-binding globulin (CSG) were studied in young male and female rats with hypothyrosis induced by mercasolyl in a daily dose of 6 and 30 mg/kg. No pronounced differences in CSG, typical of adult animals, were observed in young rats under conditions of thyroid function inhibition. Steroidand androgen-inhibitory and estrogen-inducing effects of hormones towards CSG did not manifest in hypothyrosis. Decrease in the level of thyroid hormones is characterized by increased affinity of CSG for glucocorticoids and a decrease in the concentration of binding sites. These data indicate that thyroid hormones are the primary regulators of CSG activity. Possibility of modifying CSG affinity and role of this factor in regulation of biological activity of glucocorticoids are discussed.


1986 ◽  
Vol 7 (3) ◽  
pp. 153-159 ◽  
Author(s):  
Linda Phillips Brett ◽  
Roger Levine ◽  
Seymour Levine

1997 ◽  
Vol 56 ◽  
pp. 466
Author(s):  
D. Djergovic ◽  
I. Zivkovic ◽  
A. Kezic ◽  
D. Kosec ◽  
M. Lovren ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document