A comparative study on the in-vitro antibacterial behaviour of chemically-modified calcium phosphate coatings

The high-tech method of creating anticorrosion calcium phosphate coating on the magnesium alloy MA8 (MgMnCe) has been developed. As was demonstrated by the volumetry method the sealing of the layer formed on the surface of Mg alloy using plasma electrolytic oxidation by superdispersed polytetrafluoroethylene substantially reduced the rate of the corrosion process. Here, the surface of the calcium phosphate layer containing hydroxyapatite (Ca/P = 1.61) remains biologically active. Studies of architectonics of the surface of innate immune cells have been performed in vitro.

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Electrostatic spray deposition (ESD) of calcium phosphate coatings, an in vitro study with osteoblast-like cells

Biomaterials ◽

10.1016/j.biomaterials.2003.08.050 ◽

2004 ◽

Vol 25 (11) ◽

pp. 2019-2027 ◽

Cited By ~ 47

Author(s):

M.C Siebers ◽

X.F Walboomers ◽

S.C.G Leeuwenburgh ◽

J.G.C Wolke ◽

J.A Jansen

Keyword(s):

Calcium Phosphate ◽

Spray Deposition ◽

In Vitro Study ◽

Vitro Study ◽

Electrostatic Spray Deposition ◽

Phosphate Coatings ◽

Calcium Phosphate Coatings ◽

Electrostatic Spray

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Calcium phosphate coatings enhance biocompatibility and degradation resistance of magnesium alloy: Correlating in vitro and in vivo studies

Bioactive Materials ◽

10.1016/j.bioactmat.2020.10.024 ◽

2021 ◽

Vol 6 (5) ◽

pp. 1223-1229

Author(s):

Julia Gao ◽

Yingchao Su ◽

Yi-Xian Qin

Keyword(s):

Magnesium Alloy ◽

Calcium Phosphate ◽

In Vivo Studies ◽

Phosphate Coatings ◽

Calcium Phosphate Coatings

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Calcium phosphate coatings: A comparative study between simultaneous vapor deposition and electron beam deposition techniques

Surface and Coatings Technology ◽

10.1016/j.surfcoat.2006.06.029 ◽

2006 ◽

Vol 201 (6) ◽

pp. 3123-3128 ◽

Cited By ~ 5

Author(s):

M. Hamdi ◽

Ari-Ide Ektessabi

Keyword(s):

Electron Beam ◽

Calcium Phosphate ◽

Comparative Study ◽

Vapor Deposition ◽

Phosphate Coatings ◽

Electron Beam Deposition ◽

Calcium Phosphate Coatings ◽

Deposition Techniques ◽

Beam Deposition

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In Vitro and In Vivo Surface Reactivity of Various Calcium Phosphate Coatings Deposited Using Electrostatic Spray Deposition (ESD)

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.309-311.607 ◽

2006 ◽

Vol 309-311 ◽

pp. 607-610

Author(s):

Sander C.G. Leeuwenburgh ◽

Joop G.C. Wolke ◽

M.C. Siebers ◽

J. Schoonman ◽

John A. Jansen

Keyword(s):

Calcium Phosphate ◽

Fibrous Tissue ◽

Tissue Response ◽

Specific Chemical ◽

Phosphate Coatings ◽

Time Periods ◽

Tissue Reactions ◽

Calcium Phosphate Coatings

The dissolution and precipitation behavior of various porous, ESD-derived calcium phosphate coatings was investigated a) in vitro after soaking in Simulated Body Fluid (SBF) for several time periods (2, 4, 8, and 12 weeks), and b) in vivo after subcutaneous implantation in the back of goats for identical time periods. At the end of these studies, the physicochemical properties of the coated substrates were characterized by means of Scanning Electron Microscopy (SEM), XRay Diffraction (XRD), Fourier-Transform InfraRed spectroscopy (FTIR) and Energy Dispersive Spectroscopy (EDS). Moreover, part of the implants was prepared for light microscopical evaluation of the tissue response. In vitro, a highly bioactive behavior was observed for all ESD-coatings, characterized by the deposition of a thick and homogeneous carbonate hydroxyapatite precipitation layer on top of the porous coatings. Regarding the in vivo study, no adverse tissue reactions (toxic effects/inflammatory cells) were observed using light microscopy, and all coatings became surrounded by a thin, dense fibrous tissue capsule after implantation. The ESD-coatings degraded gradually at a dissolution rate depending on the specific chemical phase, thereby enabling synthesis of CaP coatings with a tailored degradation rate.

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