Screening approaches against claudin-4 focusing on therapeutics through molecular docking and the analysis of their relative dynamics: a theoretical approach

2020 ◽  
Vol 40 (5) ◽  
pp. 436-441
Author(s):  
Majji Rambabu ◽  
Sivaraman Jayanthi
Keyword(s):  
Molecular Docking ◽  
Theoretical Approach ◽  
Relative Dynamics ◽  
Screening Approaches

scholarly journals Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches

RSC Advances ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. 5286-5297 ◽  
Author(s):  
De Kang ◽  
Xiaocong Pang ◽  
Wenwen Lian ◽  
Lvjie Xu ◽  
Jinhua Wang ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cancer Therapy ◽  
Drug Screening ◽  
Bayesian Classification ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Naive Bayesian ◽  
Naïve Bayesian ◽  
Effective Drugs ◽  
Screening Approaches

The high morbidity and mortality of cancer make it one of the leading causes of global death, thus it is an urgent need to develop effective drugs for cancer therapy.

Differential polarization imaging of sickled cells

1988 ◽  
Vol 46 ◽  
pp. 62-63
Author(s):  
Marcos F. Maestre
Keyword(s):  
Optical Properties ◽  
Theoretical Approach ◽  
Polarized Light ◽  
Polarization Microscopy ◽  
Spectroscopic Techniques ◽  
Polarization Imaging ◽  
Circularly Polarized Light ◽  
Circularly Polarized ◽  
Microscopic Scale ◽  
Chiral Structures

Recently we have developed a form of polarization microscopy that forms images using optical properties that have previously been limited to macroscopic samples. This has given us a new window into the distribution of structure on a microscopic scale. We have coined the name differential polarization microscopy to identify the images obtained that are due to certain polarization dependent effects. Differential polarization microscopy has its origins in various spectroscopic techniques that have been used to study longer range structures in solution as well as solids. The differential scattering of circularly polarized light has been shown to be dependent on the long range chiral order, both theoretically and experimentally. The same theoretical approach was used to show that images due to differential scattering of circularly polarized light will give images dependent on chiral structures. With large helices (greater than the wavelength of light) the pitch and radius of the helix could be measured directly from these images.

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