Chemical composition, antibacterial and antifungal activity of the essential oil ofThymbra spicataL. from Turkey

The essential oils extracted from the young stems and leaves of Chamaecyparis lawsoniana(A.Murray) Parl. have been analysed by Gas Chromatography and Gas Chromatography coupled to Mass Spectrometry. A total of 66 compounds were identified representing around the 99% of the total oil. The oil was richer in monoterpenes than in sesquiterpenes. The only main component was limonene with a percentage composition of 77.7%. The rest of compounds that contribute to the fragrance had percentage composition lower that the 3.0%: p-cymen-7-ol (3.0%), myrcene (2.4%), camphor (2.1%), δ-elemene (1.6%), oplopanonyl acetate (1.6%), methyl perillate (1.3%), terpinen-4-ol (1.0%) and β-oplopenone 1.0%. The antibacterial and antifungal activity of this oil was also tested against different microorganisms. The only fungus tested, Candida albicans,was very sensitive to the treatment with an inhibition halos of 20mm. The oil was more effective with the Gram (+) than with Gram (-) bacteria. The inhibition halos were 12mm, 12-13mm and 12-13mm for Bacillus subtilis, Staphylococcus aureus and Micrococcus luteus respectively. We report new data of the antibacterial and antifungal activity of the essential oil of this species. The essential oil of C. lawsoniana could be considered as a good natural antibacterial and antifungal agent.

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Antimicrobial Activity of Essential Oils and Solvent Extracts from Zieria species (Rutaceae)

Natural Product Communications ◽

10.1177/1934578x1300800615 ◽

2013 ◽

Vol 8 (6) ◽

pp. 1934578X1300800

Author(s):

Nicholas J. Sadgrove ◽

Graham L. Jones

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Essential Oils ◽

Essential Oil Composition ◽

Antibacterial And Antifungal Activity ◽

Oil Composition ◽

Pharmaceutical Development ◽

Antibacterial And Antifungal ◽

Broth Dilution ◽

Nutraceutical Products

Essential oils were hydrodistilled from six Zieria species, including two previously not investigated: Z. floydii and Z. odorifera subsp. williamsii, and characterized using GC-MS. Additionally, solvent extracts of leaf material from five of these species were prepared using n-hexane, acetone and methanol as solvents, respectively. These solvent extracts were examined, along with essential oils, for antibacterial activity using micro titer plate broth dilution assays. Antifungal activity against pathogenic Trichophyton species responsible for dermal infections such as Tinea and Kangaroo Pox (uncommon), was examined using a similar method. Results of essential oil characterizations are relatively consistent with those previously reported. Interestingly, the essential oil composition of Z. floydii showed car-3-en-2-one at a concentration of 71%, similar to that observed in a previous study for Z. furfuracea and Z. granulata, thus complementing the observations of A.G. Floyd that Z. floydii is morphologically allied with these two species (CANB 598758). Antimicrobial assays demonstrated relatively high antibacterial and antifungal activity, using both essential oils and solvent extracts. This is particularly true for the n-hexane extract from Z. smithii. We therefore conclude that Zieria species may be a useful source for the development of antiseptic, cosmaceutical and/or topical nutraceutical products. In addition, they may well serve as a source of further novel, purified compounds providing scaffolds for pharmaceutical development in the future.

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p-Menthenols chemotype of Cymbopogon distans from India: composition, antibacterial and antifungal activity of the essential oil against pathogens

Journal of Essential Oil Research ◽

10.1080/10412905.2017.1375035 ◽

2017 ◽

Vol 30 (1) ◽

pp. 40-46 ◽

Cited By ~ 1

Author(s):

Rajendra C. Padalia ◽

Ram S. Verma ◽

Amit Chauhan ◽

Prakash Goswami ◽

Ved R. Singh ◽

...

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Antibacterial And Antifungal Activity ◽

Antibacterial And Antifungal

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Antibacterial and Antifungal Activity of the Essential Oil Extracted by Hydro-Distillation from Artemisia annua Grown in West-Cameroon

British Journal of Pharmacology and Toxicology ◽

10.19026/bjpt.4.5368 ◽

2013 ◽

Vol 4 (3) ◽

pp. 89-94 ◽

Cited By ~ 3

Author(s):

Chougouo Kengne Rosine Desiree ◽

Fotsing Kwetche Pierre Rene ◽

Kouamouo Jonas ◽

Domum Tchouanche Bibiane ◽

Somo Moyo Roger ◽

...

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Artemisia Annua ◽

Antibacterial And Antifungal Activity ◽

Antibacterial And Antifungal

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Analysis of Essential Oil of Coridothymus capitatus (L.) and Its Antibacterial and Antifungal Activity

Zeitschrift für Naturforschung C ◽

10.1515/znc-2003-9-1016 ◽

2003 ◽

Vol 58 (9-10) ◽

pp. 687-690 ◽

Cited By ~ 24

Author(s):

Ahmet C. Goren ◽

Gokhan Bilsel ◽

Mine Bilsel ◽

Huseyin Demir ◽

E. Esin Kocabaş

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Thermal Desorption ◽

Antibacterial And Antifungal Activity ◽

Strong Activity ◽

E Coli ◽

Oxygenated Hydrocarbons ◽

Ms Analysis ◽

Direct Thermal Desorption ◽

Antibacterial And Antifungal

AbstractThe water-distilled essential oil the leaves of Coridothymus capitatus were analyzed by GC/MS and also analyzed by direct thermal desorption GC/MS. Comparison was made between two analyses techniques. The essential oil consisted mainly of monoterpenes 98.9%, while oxygenated hydrocarbons were identified as 55.6% and non-oxygenated hydrocarbons as 43.6%. As major components were found carvacrol (35.6%), p-cymene (21.0%), thymol (18.6%), γ-terpinene (12.3%), α-terpinene (3.2%), β-myrcene (3.0%) and α-thujene (1.3%) by hydrodistillation and by the GC/MS method. The direct thermal desorption GC/MS analysis also showed the same major components, namely carvacrol (51.6%), thymol (21.7%), pcymene (9.7%) γ-terpinene (8.2%), α-terpinene (1.64%). The essential oil of C. capitatus showed strong activity against S. aureus, P. vulgaris, P. aeruginosa, E. coli, K. pneumonia, B. subtilis, E. faecalis, S. epidermidis and C. albicans.

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Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.

Plants ◽

10.3390/plants10102068 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2068

Author(s):

Jamila El Karkouri ◽

Mohamed Bouhrim ◽

Omkulthom Mohamed Al Kamaly ◽

Hamza Mechchate ◽

Amal Kchibale ◽

...

Keyword(s):

Escherichia Coli ◽

Staphylococcus Aureus ◽

Chemical Composition ◽

Antifungal Activity ◽

Chemical Analysis ◽

Essential Oil ◽

Inhibition Zone ◽

Salmonella Typhi ◽

Cistus Ladanifer ◽

Antibacterial And Antifungal

Cistus ladanifer L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (Staphylococcus aureus, Salmonella Typhi, Escherichia coli, and Acinetobacter baumannii) and nine fungi (Yeasts (Candida tropicalis, Candida glabrata, Candida dubliniensis, Candida sp., Rhodotorula rubra, Cryptococcus neoformans) and molds (Penicillium sp. (P), Fusarium sp. (F), Aspergillus niger (A. niger)), respectively. The essential oil of C. ladanifer demonstrated a powerful antibacterial activity with an inhibition zone of 55 ± 0.22 mm for Staphylococcus aureus, 42 ± 0.11 mm for Escherichia coli, 35 ± 0.27 mm for Acinetobacter baumannii (Full resistant to antibiotics) and 30 ± 0.25 mm for Salmonella Typhi. It also inhibited all tested bacteria at 10 µL/mL. For the antifungal activity test, C. tropicalis and C. neoformans appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by R. rubra and Penicillium sp. (12 mm), then C. dubliniensis and C. glabrata (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). C. ladanifer exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases.

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Natural Products in Drug Discovery: Antibacterial and Antifungal Activity of Essential Oil of Compound Isolated from Senecio royleanus

Journal of Pure and Applied Microbiology ◽

10.22207/jpam.13.3.34 ◽

2019 ◽

Vol 13 (3) ◽

pp. 1611-1617

Author(s):

Chandra Mohan Singh Bisht ◽

S.M. Shakeel Iqubal ◽

Aejaz A. Khan ◽

Tasneem Mohammed ◽

Areej Dawoud ◽

...

Keyword(s):

Natural Products ◽

Drug Discovery ◽

Antifungal Activity ◽

Essential Oil ◽

Antibacterial And Antifungal Activity ◽

Antibacterial And Antifungal

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Chemical Composition, Anti-inflammatory, Analgesic, Antipyretic, Myorelaxant, Antibacterial and Antifungal activity of Rabdosia rugosus Wall. (Syn. Plectranthus rugosus Wall.)

Journal of Medicinal Herbs and Ethnomedicine ◽

10.25081/jmhe.2019.v5.3831 ◽

1970 ◽

pp. 08-15

Author(s):

Prakash Singh, Ravendra Kumar ◽

Om Prakash, Anil Kumar Pant ◽

Mahesh Kumar ◽

Valary A. Isidorov, Lech Szczepaniak

Keyword(s):

Antimicrobial Activity ◽

Chemical Composition ◽

Essential Oil ◽

The Other ◽

Major Constituent ◽

Antibacterial And Antifungal Activity ◽

Germacrene D ◽

Anti Inflammatory ◽

Total Oil ◽

Antibacterial And Antifungal

For the present investigation Rabdosia rugosus Wall. Syn. Plectranthus rugosus Wall. was collected from Pancheshwar, Uttarakhand on the way to Badrinath. The GC and GC-MS analysis, revealed the presence of more than forty compounds out of which 35 compounds were identified amounting to 97.3% of the total oil. The essential oil of R. rugosus was rich in sesquiterpinoids (~90%) and was poor in monoterpenoids (8.1%). α-bisabolol (41.9%) was the major constituent of the oil and the other identified major compounds were germacrene-D (9.7%), β-caryophyllene (7.6%), dehydroabietane (5.2%), ar-curcumene (5.0), trans-ferruginol (3.3%) α-cadinol (3.2%), τ-muurolol (2.3%), p-Cymene (3.2%) and γ-terpinene (2.0%). The essential oil of Rabdosia rugosus showed insignificant anti-inflammatory and analgesic activity but shows significant antipyretic, myorelaxant and antimicrobial activity.

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