Analysis of Essential Oil of Coridothymus capitatus (L.) and Its Antibacterial and Antifungal Activity

2003 ◽  
Vol 58 (9-10) ◽  
pp. 687-690 ◽  
Author(s):  
Ahmet C. Goren ◽  
Gokhan Bilsel ◽  
Mine Bilsel ◽  
Huseyin Demir ◽  
E. Esin Kocabaş

AbstractThe water-distilled essential oil the leaves of Coridothymus capitatus were analyzed by GC/MS and also analyzed by direct thermal desorption GC/MS. Comparison was made between two analyses techniques. The essential oil consisted mainly of monoterpenes 98.9%, while oxygenated hydrocarbons were identified as 55.6% and non-oxygenated hydrocarbons as 43.6%. As major components were found carvacrol (35.6%), p-cymene (21.0%), thymol (18.6%), γ-terpinene (12.3%), α-terpinene (3.2%), β-myrcene (3.0%) and α-thujene (1.3%) by hydrodistillation and by the GC/MS method. The direct thermal desorption GC/MS analysis also showed the same major components, namely carvacrol (51.6%), thymol (21.7%), pcymene (9.7%) γ-terpinene (8.2%), α-terpinene (1.64%). The essential oil of C. capitatus showed strong activity against S. aureus, P. vulgaris, P. aeruginosa, E. coli, K. pneumonia, B. subtilis, E. faecalis, S. epidermidis and C. albicans.

2021 ◽  
Vol 2 (2) ◽  
pp. 93-103
Author(s):  
Nathaniel Hiwandika ◽  
Susana Elya Sudrajat ◽  
Ika Rahayu

Cloves is one of the native Indonesian plants and is used in many aspects of life. Cloves are used in multiple industries and as detergents, soaps, perfumes, food seasonings, aromatherapy, etc. Cloves are mainly used for ingredients in kretek cigarettes in Indonesia. Various studies of cloves reported they have good pharmacological and therapeutic effects. The main compounds of clove extract are eugenol and β-caryophyllene, which are powerful antibacterial and antifungal agents. The clove ethanolic extract showed the activity to inhibit Gram positive and negative bacteria such as B. cereus, S. aureus, E. coli, P. aeruginosa, S. pneumoniae, S. aureus, S. epidermidis, A. hydrophila, K. pneumoniae, P. gingivalis, and P. mirabilis. Clove essential oil has shown the ability to inhibit the growth of V. inaequalis, C. albicans, C. glabrata, and C. tropicalis. Cloves extract can be used as an essential ingredient of various medicines. However, it requires further research and trials.


2012 ◽  
Vol 27 (3) ◽  
pp. 216-223 ◽  
Author(s):  
Marija Marin ◽  
Miroslav Novaković ◽  
Vele Tešević ◽  
Ivan Vučković ◽  
Nataša Milojević ◽  
...  

2012 ◽  
Vol 7 (10) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Jesús Palá-Paúl ◽  
Jaime Usano-Alemany ◽  
Elena Granda ◽  
Ana-Cristina Soria

The essential oils extracted from the young stems and leaves of Chamaecyparis lawsoniana(A.Murray) Parl. have been analysed by Gas Chromatography and Gas Chromatography coupled to Mass Spectrometry. A total of 66 compounds were identified representing around the 99% of the total oil. The oil was richer in monoterpenes than in sesquiterpenes. The only main component was limonene with a percentage composition of 77.7%. The rest of compounds that contribute to the fragrance had percentage composition lower that the 3.0%: p-cymen-7-ol (3.0%), myrcene (2.4%), camphor (2.1%), δ-elemene (1.6%), oplopanonyl acetate (1.6%), methyl perillate (1.3%), terpinen-4-ol (1.0%) and β-oplopenone 1.0%. The antibacterial and antifungal activity of this oil was also tested against different microorganisms. The only fungus tested, Candida albicans,was very sensitive to the treatment with an inhibition halos of 20mm. The oil was more effective with the Gram (+) than with Gram (-) bacteria. The inhibition halos were 12mm, 12-13mm and 12-13mm for Bacillus subtilis, Staphylococcus aureus and Micrococcus luteus respectively. We report new data of the antibacterial and antifungal activity of the essential oil of this species. The essential oil of C. lawsoniana could be considered as a good natural antibacterial and antifungal agent.


2013 ◽  
Vol 8 (6) ◽  
pp. 1934578X1300800
Author(s):  
Nicholas J. Sadgrove ◽  
Graham L. Jones

Essential oils were hydrodistilled from six Zieria species, including two previously not investigated: Z. floydii and Z. odorifera subsp. williamsii, and characterized using GC-MS. Additionally, solvent extracts of leaf material from five of these species were prepared using n-hexane, acetone and methanol as solvents, respectively. These solvent extracts were examined, along with essential oils, for antibacterial activity using micro titer plate broth dilution assays. Antifungal activity against pathogenic Trichophyton species responsible for dermal infections such as Tinea and Kangaroo Pox (uncommon), was examined using a similar method. Results of essential oil characterizations are relatively consistent with those previously reported. Interestingly, the essential oil composition of Z. floydii showed car-3-en-2-one at a concentration of 71%, similar to that observed in a previous study for Z. furfuracea and Z. granulata, thus complementing the observations of A.G. Floyd that Z. floydii is morphologically allied with these two species (CANB 598758). Antimicrobial assays demonstrated relatively high antibacterial and antifungal activity, using both essential oils and solvent extracts. This is particularly true for the n-hexane extract from Z. smithii. We therefore conclude that Zieria species may be a useful source for the development of antiseptic, cosmaceutical and/or topical nutraceutical products. In addition, they may well serve as a source of further novel, purified compounds providing scaffolds for pharmaceutical development in the future.


Author(s):  
Laila Jarin ◽  
Md Shafiqur Rahman ◽  
MN Anwar

Petroleum ether, carbon tetrachloride, chloroform and ethyl acetate extracts of Plumeria rubra leaves were studied for their antimicrobial activities against eleven human pathogenic bacteria, viz., Shigella dysenteriae, S. sonnei, Salmonella typhi, S. paratyphi, Bacillus subtilis, B. megaterium, B. cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Vibrio cholerae and four human pathogenic fungi, viz., Aspergillus niger, A. ochraceus, A. ustus and Candida albicans using disc diffusion and poisoned food method, respectively. Chloroform and ethyl acetate extract exhibited moderate to good antibacterial and antifungal activity against all the pathogens tested. The ethyl acetate extracts exhibited the largest zone of inhibition (25 mm in diameter with 2000 mg/disc extract) against E. coli. The highest inhibition of fungal radial mycelial growth (62.00% with 100 mg extract/ml medium) was recorded against A. ustus with ethyl acetate extract. The MICs were determined by broth macrodilution technique. The ethyl acetate extract exhibited the lowest MIC (750 mg/ml) against E. coli. However, for fungi the lowest MIC was 500 mg/ml against A. ustus with the same extract. DOI: http://dx.doi.org/10.3329/cujbs.v3i1.13409 The Chittagong Univ. J. B. Sci.,Vol. 3(1&2):87-94, 2008


2011 ◽  
Vol 8 (s1) ◽  
pp. S149-S154 ◽  
Author(s):  
P. Panneerselvam ◽  
G. Geete Ganesh

The syntheses of series of 2, 5-disubstituted 1, 3, 4-oxadiazole derivatives are described. A total of twelve new compounds were synthesized and characterized by IR,1H-NMR and Mass spectral data. All newly synthesized compounds were screened for their antimicrobial activityi.e. antibacterial activity againstS. aureusandE. coliand antifungal activity against fungusA. nigar. CompoundsG5andG7exhibited significant both antibacterial and antifungal activity whileG2,G10andG3,G9showed antibacterial and antifungal activity respectively. These compounds were 2, 5-disubstituted 1, 3, 4-oxadiazole moiety at position two and five showed reasonable antibacterial and antifungal activity.


2009 ◽  
Vol 23 (6) ◽  
pp. 572-579 ◽  
Author(s):  
Mehmet Ünlü ◽  
Gülhan Vardar-Ünlü ◽  
Nilüfer Vural ◽  
Erol Dönmez ◽  
Z. Yeşım Özbaş

Author(s):  
Neeraj Kumar ◽  
Dhruti Bhatt ◽  
Chandra Shekhar Sharma ◽  
Hamendra Pratap Singh ◽  
Harshda Pandiya ◽  
...  

A series of of Chalconyl Incorporated Schiff’s Bases of Sulphonamides was synthesized by reacting substituted chalcone derivatives with Sulphacetamide sodium in methanol. All the title compounds synthesized (2a-2d) were tested for antibacterial and antifungal activity using E. coli, P. aeruginosa, S. aureus, S. pyogenus and C. albicans, A. niger and A. clavatus respectively as microbial strains and Sulphacetamide sodium as standard. The compound 2d showed significant antibacterial activity and 2a showed moderate antifungal activity as compared with Sulphacetamide Sodium.


2013 ◽  
Vol 4 (3) ◽  
pp. 89-94 ◽  
Author(s):  
Chougouo Kengne Rosine Desiree ◽  
Fotsing Kwetche Pierre Rene ◽  
Kouamouo Jonas ◽  
Domum Tchouanche Bibiane ◽  
Somo Moyo Roger ◽  
...  

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