A new flavanone glycoside isolated from Tournefortia sibirica

2018 ◽  
Vol 33 (20) ◽  
pp. 3021-3024 ◽  
Author(s):  
Shengbao Diao ◽  
Mei Jin ◽  
Chun Shi Jin ◽  
Cheng-Xi Wei ◽  
Jinfeng Sun ◽  
...  
Keyword(s):  
2017 ◽  
Vol 19 ◽  
pp. 220-225 ◽  
Author(s):  
Adriana C. Nascimento ◽  
Ligia M.M. Valente ◽  
Mário Gomes ◽  
Rodolfo S. Barboza ◽  
Thiago Wolff ◽  
...  

2013 ◽  
Vol 8 (4) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Wei Zou ◽  
Yonggang Wang ◽  
Haibin Liu ◽  
Yulong Luo ◽  
Si Chen ◽  
...  

Citrus grandis ‘Tomentosa’ is a traditional Chinese medicine, used as an antitussive. In this research, melitidin, a flavanone glycoside, was isolated from this species for the first time by using chromatographic methods. The structure was confirmed through comprehensive analyses of its ultraviolet, infrared, 1H and 13C NMR, HMBC and HMQC spectroscopic and high-resolution mass spectrometric data. Meliditin showed a good antitussive effect on cough induced by citric acid in Guinea pig, suggesting that it was a contributor to the antitussive effect of C. grandis ‘Tomentosa’.


2009 ◽  
Vol 7 (2) ◽  
pp. 105-107 ◽  
Author(s):  
Mi ZHANG ◽  
Rong-Rong WANG ◽  
Man CHEN ◽  
Han-Qing ZHANG ◽  
Shi SUN ◽  
...  

1989 ◽  
Vol 91 (4) ◽  
pp. 1323-1328 ◽  
Author(s):  
Efraim Lewinsohn ◽  
Lothar Britsch ◽  
Yehuda Mazur ◽  
Jonathan Gressel
Keyword(s):  

2002 ◽  
Vol 57 (11-12) ◽  
pp. 986-989 ◽  
Author(s):  
Quang An Nguyen ◽  
Hanh Trinh Van-Dufat ◽  
Sylvie Michel ◽  
François Tillequin ◽  
Vincent Dumontet ◽  
...  

The alkaloids norchelerythrine, magnoflorine and (-)(S)-O-methylbalfourodinium cation were isolated from Zanthoxylum scandens bark collected in Vietnam, together with the flavanone glycoside hesperidin and the phenylpropanoids (E)-O-geranylconiferyl alcohol and (E)-O-geranylconiferyl alcohol (9Z, 12Z)-linoleate. This latter is a novel compound whose structure was elucidated on the basis of its spectral data and confirmed by chemical correlation.


2002 ◽  
Vol 59 (8) ◽  
pp. 889-895 ◽  
Author(s):  
Muhammad Shaiq Ali ◽  
Muhammad Saleem ◽  
Waqar Ahmad ◽  
Masood Parvez ◽  
Raghav Yamdagni

2001 ◽  
Vol 56 (8) ◽  
pp. 875-879 ◽  
Author(s):  
Hironobu Takahashi ◽  
Sachiyo Hirata ◽  
Hiroyuki Minami ◽  
Yoshiyasu Fukuyama

1978 ◽  
Vol 17 (6) ◽  
pp. 1064-1065 ◽  
Author(s):  
Wasiur Rahman ◽  
Khwaja Ishratullah ◽  
Hildebert Wagner ◽  
Otto Seligmann ◽  
V.Mohan Chari ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2800
Author(s):  
Fang-Ju Cheng ◽  
Thanh-Kieu Huynh ◽  
Chia-Shin Yang ◽  
Dai-Wei Hu ◽  
Yi-Cheng Shen ◽  
...  

Hesperidin (HD) is a common flavanone glycoside isolated from citrus fruits and possesses great potential for cardiovascular protection. Hesperetin (HT) is an aglycone metabolite of HD with high bioavailability. Through the docking simulation, HD and HT have shown their potential to bind to two cellular proteins: transmembrane serine protease 2 (TMPRSS2) and angiotensin-converting enzyme 2 (ACE2), which are required for the cellular entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our results further found that HT and HD suppressed the infection of VeroE6 cells using lentiviral-based pseudo-particles with wild types and variants of SARS-CoV-2 with spike (S) proteins, by blocking the interaction between the S protein and cellular receptor ACE2 and reducing ACE2 and TMPRSS2 expression. In summary, hesperidin is a potential TMPRSS2 inhibitor for the reduction of the SARS-CoV-2 infection.


Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
AC Nascimento ◽  
LM Valente ◽  
NC Garden ◽  
MD Pereira ◽  
FA Castro ◽  
...  
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