Conditioned suppression of compulsive behavior in an adolescent diagnosed with obsessive-compulsive disorder

2016 ◽  
Vol 17 (2) ◽  
pp. 192-199
Author(s):  
Heather Penney ◽  
Duncan Pritchard ◽  
Marguerite Hoerger ◽  
F. Charles Mace
CNS Spectrums ◽  
2005 ◽  
Vol 10 (3) ◽  
pp. 191-202 ◽  
Author(s):  
David Eilam ◽  
Henry Szechtman

AbstractRats treated chronically with the D2/D3, dopamine receptor agonist quinpirole show a pattern of behavior that meets a set of ethologically derived criteria of compulsive behavior in obsessive-compulsive disorder (OCD). Moreover, in both quinpirole-treated rats and OCD patients, the structure of compulsive rituals appear similar in being composed of relatively few motor acts that are organized in a flexible yet recurrent manner. In addition, the development of compulsive behavior in quinpirole-treated rats is attenuated by the OCD pharmacotherapeutic drug clomipramine. These similarities support the validity of quinpirole-treated rats as a psychostimulant-induced animal model of OCD. Considering that the induction of compulsive behavior in the rat model involves chronic hyperstimulation of dopamine receptors, this raises the possibility that dopaminergic mechanisms may play a role in OCD, at least in some subtypes of this disorder.


CNS Spectrums ◽  
2017 ◽  
Vol 22 (3) ◽  
pp. 295-304 ◽  
Author(s):  
Gabriela M. Ferreira ◽  
Murat Yücel ◽  
Andrew Dawson ◽  
Valentina Lorenzetti ◽  
Leonardo F. Fontenelle

AimsTo determine the rates and associated illness characteristics of obsessive-compulsive disorder (OCD) patients who describe their symptoms as either rewarding or habitual.MethodsSeventy-three treatment-seeking OCD patients had their dominant compulsive behavior assessed with a structured interview (the Temporal Impulsive-Compulsive Scale–Revised) to track the progression of rewarding (ie, gain in positive affect), aversive (ie, decrease in negative affect), and neutral (or non-affective) states and a self-report scale (the Self-Report Habit Index) to evaluate their habitual features. Additional measures included structured diagnostic interviews for axis I and II disorders, measures of OCD symptoms severity, and a battery of instruments to comprehensively assess relevant aspects of sensitivity to reward and fear.ResultsAlmost half (49%) of our OCD patients (particularly washers) endorsed that they anticipated obtaining a reward (ie, positive affect) from the enactment of their dominant compulsive behavior. Washers stood out in that their positive affects during and after compulsive behaviors were highly (and positively) correlated with duration of illness. In contrast, habit strength did not differ between washers, checkers, and arrangers, although it also correlated with duration of illness among checkers. Furthermore, the severity of OCD and comorbidity with impulse control disorders predicted up to 35% of the variance in the habit strength of OCD behaviors.ConclusionCompulsive washing may be more clearly characterized by problems in reward processing. In contrast, duration of checking, severity of OCD, and comorbidity with impulse control disorders shape compulsive behaviors by imparting them with habitual tendencies.


2006 ◽  
Vol 29 (6) ◽  
pp. 627-628 ◽  
Author(s):  
Aribert Rothenberger ◽  
Veit Roessner ◽  
Tobias Banaschewski

Tourette Syndrome (TS) and Obsessive-Compulsive Disorder (OCD) are highly associated and often it is difficult to differentiate their symptomatology. In TS, habit forming neuronal systems may form habits of their own – sometimes similar to ritualized behavior. However, whereas in OCD merely the “affect-loop” is touched, in TS the “sensorimotor-loop” plays the major role, although some overlap can be seen in the clinical spectrum between TS and OCD. The latter is mainly related to the “just-right” phenomenon which shows a clear developmental course. An analogous behavioral model for TS and OCD with reference to “just-right” is suggested.


1999 ◽  
Vol 187 (11) ◽  
pp. 697-699 ◽  
Author(s):  
Mark H. Townsend ◽  
Karen A. Weissbecker ◽  
James G. Barbee ◽  
José M. Peña ◽  
Leslie M. Snider ◽  
...  

2014 ◽  
Vol 13 (2) ◽  
pp. 221-223
Author(s):  
Rohayah Husain ◽  
Khairi Che Mat

This case report illustrates the management of a patient with Obsessive Compulsive Disorder who presented with hypochondriacal and persecutory ideas. Cognitive behavioural hypnotherapy approaches were applied in the management as the patient not keen for pharmacological treatment. Obsessive thoughts were managed via distraction technique, thought stopping and modified it to a more helpful compulsive behavior via direct suggestion during hypnotic state. The compulsive behavior was managed via hypno-behavioural approaches, reinforced by direct suggestion and pseudo-orientation in time. The Subjective Unit of Distress Scale (SUDS), Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales were used to measure the progress of anxiety and depressive symptoms. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18308 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.221-223


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