Intersectionality in Clinical Medicine: The Need for a Conceptual Framework

Shock states are defined by stereotypic changes in well-known physiologic parameters. While these well-known changes provide a convenient entry point into further evaluation of patients in shock or at risk for shock, use of such physiologic evaluation is not commonly seen in clinical medicine. A formal description of physiologic reasoning in the diagnosis of shock states is presented in this paper. Included with this conceptual framework is a discussion of key tests or findings that can be used to differentiate between possible diagnoses, and the pairing of treatment strategies to distinct classes of physiologic abnormalities. It is hoped that the methodology presented here will demonstrate the primacy of physiologic reasoning in the diagnosis and treatment of hemodynamic instability. Advantages of this method are speed and accuracy, efficient use of resources, and mitigation against sources of medical errors.

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Integrating intersectionality into autonomy: Reflections on feminist bioethics and egg freezing

DiGeSt Journal of Diversity and Gender Studies ◽

10.21825/digest.v7i2.16532 ◽

2021 ◽

Vol 7 (2) ◽

pp. 21-33

Author(s):

Michiel De Proost

Keyword(s):

Conceptual Framework ◽

Clinical Medicine ◽

Biomedical Ethics ◽

Relational Autonomy ◽

Feminist Inquiry ◽

Feminist Bioethics ◽

Egg Freezing ◽

Social Egg Freezing

The field of bioethics struggles with the complexity of diversity and power differences. ‘Intersectionality in Clinical Medicine: The Need for a Conceptual Framework’ (Wilson et al., 2019) and its accompanying commentaries, though inventive and thought-provoking, overlook key principles of biomedical ethics. In this paper, I reflect on the debate and consider how an intersectional approach could inform normative theorizing. Traditional principlist reasoning leads to serious problems when we are trying to deal with the complexities of intersectionality, and this is especially true if we look at the principle of autonomy. I develop the idea that intersectionality is more in line with feminist inquiry in bioethics that attempts to reconfigure autonomy. However, feminist critiques of autonomy often remain less than thoroughly engaged with intersectionality. The case of social egg freezing is used to further support this claim. By foregrounding an intersectional approach to the existing relational autonomy claims in this debate, the complicated relational and justice concerns of reproduction are better brought into focus.

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Drug Induced Changes in Cell Organelles

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100100299 ◽

1968 ◽

Vol 26 ◽

pp. 110-111

Author(s):

Sarah A. Luse

Keyword(s):

Clinical Medicine ◽

Cell Organelles ◽

Riboflavin Deficiency ◽

Drug Induced ◽

New Era ◽

Health And Disease ◽

In The Beginning ◽

Cellular Pathology ◽

Induced Changes ◽

The Impact

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.

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A conceptual framework for advanced practice: an action research project operationalizing anadvanced practitioner/consultant nurse role

Journal of Clinical Nursing ◽

10.1046/j.1365-2702.1997.00143.x ◽

1997 ◽

Vol 6 (3) ◽

pp. 179-190 ◽

Cited By ~ 20

Author(s):

Kim Manley

Keyword(s):

Action Research ◽

Conceptual Framework ◽

Advanced Practice ◽

Action Research Project ◽

Research Project ◽

Nurse Role

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Mortality Rate Versus Funeral Rate in Clinical Medicine

Gastroenterology ◽

10.1016/s0016-5085(64)80034-2 ◽

1964 ◽

Vol 46 (6) ◽

pp. 788-791 ◽

Cited By ~ 16

Author(s):

Thomas C. Chalmers

Keyword(s):

Mortality Rate ◽

Clinical Medicine ◽

Rate Versus

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Evaluating research in developmental disabilities: a conceptual framework for reviewing treatment outcomes

Developmental Medicine & Child Neurology ◽

10.1017/s0012162299000110 ◽

1999 ◽

Vol 41 (1) ◽

pp. 55-59 ◽

Cited By ~ 51

Author(s):

Charlene Butler ◽

Henry Chambers ◽

Murray Goldstein ◽

Susan Harris ◽

Judy Leach ◽

...

Keyword(s):

Developmental Disabilities ◽

Conceptual Framework ◽

Treatment Outcomes

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Understanding Why Older People Develop a Wish to Die

Crisis ◽

10.1027/0227-5910/a000078 ◽

2011 ◽

Vol 32 (4) ◽

pp. 204-216 ◽

Cited By ~ 52

Author(s):

M. L. Rurup ◽

H. R. W. Pasman ◽

J. Goedhart ◽

D. J. H. Deeg ◽

A. J. F. M. Kerkhof ◽

...

Keyword(s):

Older People ◽

Cohort Studies ◽

Conceptual Framework ◽

Life Events ◽

Traumatic Life Events ◽

Quantitative Studies ◽

Wish To Die ◽

Open Coding ◽

Death Wishes ◽

Depth Interviews

Background: Quantitative studies in several European countries showed that 10–20% of older people have or have had a wish to die. Aims: To improve our understanding of why some older people develop a wish to die. Methods: In-depth interviews with people with a wish to die (n = 31) were carried out. Through open coding and inductive analysis, we developed a conceptual framework to describe the development of death wishes. Respondents were selected from two cohort studies. Results: The wish to die had either been triggered suddenly after traumatic life events or had developed gradually after a life full of adversity, as a consequence of aging or illness, or after recurring depression. The respondents were in a situation they considered unacceptable, yet they felt they had no control to change their situation and thus progressively “gave up” trying. Recurring themes included being widowed, feeling lonely, being a victim, being dependent, and wanting to be useful. Developing thoughts about death as a positive thing or a release from problems seemed to them like a way to reclaim control. Conclusions: People who wish to die originally develop thoughts about death as a positive solution to life events or to an adverse situation, and eventually reach a balance of the wish to live and to die.

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