Polybrominated diphenyl ethers concentrations in metals and plastics scrap impacted soils: Pollution load, sources, ecological, and onsite human health implications

2021 ◽  
pp. 1-16
Author(s):  
Onoriode O. Emoyan ◽  
Godswill O. Tesi ◽  
Efe Ohwo ◽  
Chijioke Olisah ◽  
Stephen U. Oghoje
Keyword(s):  
Human Health ◽  
Polybrominated Diphenyl Ethers ◽  
Pollution Load ◽  
Health Implications ◽  
Diphenyl Ethers

scholarly journals Human Health Risk Assessment by Dietary Intake and Spatial Distribution Pattern of Polybrominated Diphenyl Ethers and Dechloran Plus from Selected Cities of Pakistan

2020 ◽  
Vol 17 (24) ◽  
pp. 9543
Author(s):  
Adeel Mahmood ◽  
Jabir Hussain Syed ◽  
Waseem Raza ◽  
Amtul Bari Tabinda ◽  
Andleeb Mehmood ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Human Health ◽  
Source Apportionment ◽  
Polybrominated Diphenyl Ethers ◽  
Flame Retardants ◽  
Human Health Risk ◽  
Metropolitan Cities ◽  
Toxicological Data ◽  
Range Transport ◽  
Diphenyl Ethers

A class of intractable bio accumulative halogenated compounds polybrominated diphenyl ethers (PBDEs) was studied. Specifically, PBDEs and dechloran plus (DP) contamination in wheat and the assaulted environment—agricultural soil and dust—from metropolitan cities of Pakistan was the focus. The exposure of brominated flame retardants (BFRs) to humans, their probable toxicological impact on health, source apportionment, and the spatial tendency of BFRs were studied. Chromatographic analysis was performed, and concentrations (ng g−1) of ΣPBDE and ΣDP in soil, dust, and cereal crops were estimated in a range from 0.63 to 31.70 n.d. to 6.32 and n.d. to 3.47, respectively, and 0.11 to 7.05, n.d. to 4.56 and 0.05 to 4.95, respectively. Data analysis of source apportionment reflected that the existence of solid and e-waste sites, long-range transport, urban and industrial fraction can be the potential source of PBDE and DP pollution. Moreover, potential hazardous risks to human health across the study area via the dietary intake of cereal foods were deemed trifling, and were gauged on the basis of existing toxicological data.

Polybrominated diphenyl ethers (PBDEs) concentration in soil from San Luis Potosi, Mexico: levels and ecological and human health risk characterization

2015 ◽  
Vol 26 (3) ◽  
pp. 239-253 ◽  
Author(s):  
Francisco J. Pérez-Vázquez ◽  
Sandra T. Orta-García ◽  
Ángeles C. Ochoa-Martínez ◽  
Lucia G. Pruneda-Álvarez ◽  
Tania Ruiz-Vera ◽  
...  
Keyword(s):  
Health Risk ◽  
Human Health ◽  
Polybrominated Diphenyl Ethers ◽  
Human Health Risk ◽  
Risk Characterization ◽  
San Luis ◽  
San Luis Potosi ◽  
Diphenyl Ethers ◽  
San Luis Potosí

scholarly journals Human Excretion of Polybrominated Diphenyl Ether Flame Retardants: Blood, Urine, and Sweat Study

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Shelagh K. Genuis ◽  
Detlef Birkholz ◽  
Stephen J. Genuis
Keyword(s):  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Polybrominated Diphenyl Ethers ◽  
Flame Retardants ◽  
Diphenyl Ether ◽  
Body Fluids ◽  
Urine Samples ◽  
Health Implications ◽  
Reproductive Effects ◽  
Diphenyl Ethers

Commonly used as flame retardants, polybrominated diphenyl ethers (PBDEs) are routinely detected in the environment, animals, and humans. Although these persistent organic pollutants are increasingly recognized as having serious health implications, particularly for children, this is the first study, to our knowledge, to investigate an intervention for human elimination of bioaccumulated PBDEs. Objectives. To determine the efficacy of blood, urine, and perspiration as PBDE biomonitoring mediums; assess excretion of five common PBDE congeners (28, 47, 99, 100, and 153) in urine and perspiration; and explore the potential of induced sweating for decreasing bioaccumulated PBDEs. Results. PBDE congeners were not found in urine samples; findings focus on blood and perspiration. 80% of participants tested positive in one or more body fluids for PBDE 28, 100% for PBDE 47, 95% for PBDE 99, and 90% for PBDE 100 and PBDE 153. Induced perspiration facilitated excretion of the five congeners, with different rates of excretion for different congeners. Conclusion. Blood testing provides only a partial understanding of human PBDE bioaccumulation; testing of both blood and perspiration provides a better understanding. This study provides important baseline evidence for regular induced perspiration as a potential means for therapeutic PBDE elimination. Fetotoxic and reproductive effects of PBDE exposure highlight the importance of further detoxification research.

scholarly journals Epigenetic Effects of Polybrominated Diphenyl Ethers on Human Health

2019 ◽  
Vol 16 (15) ◽  
pp. 2703 ◽  
Author(s):  
Robert G. Poston ◽  
Ramendra N. Saha
Keyword(s):  
Human Health ◽  
Neurodevelopmental Disorders ◽  
Polybrominated Diphenyl Ethers ◽  
Flame Retardants ◽  
Consumer Products ◽  
Environmental Stability ◽  
Clear Understanding ◽  
Mechanisms Of Toxicity ◽  
Wide Range ◽  
Diphenyl Ethers

Disruption of epigenetic regulation by environmental toxins is an emerging area of focus for understanding the latter’s impact on human health. Polybrominated diphenyl ethers (PBDEs), one such group of toxins, are an environmentally pervasive class of brominated flame retardants that have been extensively used as coatings on a wide range of consumer products. Their environmental stability, propensity for bioaccumulation, and known links to adverse health effects have evoked extensive research to characterize underlying biological mechanisms of toxicity. Of particular concern is the growing body of evidence correlating human exposure levels to behavioral deficits related to neurodevelopmental disorders. The developing nervous system is particularly sensitive to influence by environmental signals, including dysregulation by toxins. Several major modes of actions have been identified, but a clear understanding of how observed effects relate to negative impacts on human health has not been established. Here, we review the current body of evidence for PBDE-induced epigenetic disruptions, including DNA methylation, chromatin dynamics, and non-coding RNA expression while discussing the potential relationship between PBDEs and neurodevelopmental disorders.

scholarly journals Epigenetic Effects of Polybrominated Diphenyl Ethers on Human Health

2019 ◽  
Author(s):  
Robert Gregory Poston ◽  
Ramendra Nath Saha
Keyword(s):  
Human Health ◽  
Neurodevelopmental Disorders ◽  
Polybrominated Diphenyl Ethers ◽  
Consumer Products ◽  
Environmental Stability ◽  
Clear Understanding ◽  
Mechanisms Of Toxicity ◽  
Wide Range ◽  
Growing Body ◽  
Diphenyl Ethers

Disruption of epigenetic regulation by environmental toxins is an emerging point of focus for understanding the latter’s impact on human health. Polybrominated diphenyl ethers (PBDEs), one such toxin, are an environmentally pervasive class of brominated flame retardants that have been extensively used as coatings on a wide range of consumer products. Their environmental stability, propensity for bioaccumulation, and known links to adverse health effects have evoked extensive research to characterize underlying biological mechanisms of toxicity. Of particular concern is the growing body of evidence correlating human exposure levels to behavioral deficits related to neurodevelopmental disorders. The developing nervous system is particularly sensitive to influence by environmental signals, including dysregulation by toxins. Several major modes of actions have been identified, but a clear understanding of how observed effects relate to negative impacts on human health has not been established. Here we review the growing body of evidence for epigenetic disruptions induced by PBDEs, including DNA methylation, chromatin dynamics, and non-coding RNA expression while discussing potential relationship between PBDEs and neurodevelopmental disorders.

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