Sleep Quality Moderates the Relationship between Anxiety Sensitivity and PTSD Symptoms in Combat-exposed Veterans

2020 ◽  
pp. 1-13
Author(s):  
Sage McNett ◽  
Mackenzie J. Lind ◽  
Ruth C. Brown ◽  
Sage Hawn ◽  
Erin C. Berenz ◽  
...  
2020 ◽  
Vol 35 (6) ◽  
pp. 923-923
Author(s):  
Walker N ◽  
Scott T ◽  
Spellman J ◽  
Rivera J ◽  
Waltzman D ◽  
...  

Abstract Objective Reviewed literature suggests that individuals with Posttraumatic Stress Disorder (PTSD) demonstrate cognitive deficits in attention, learning/memory, and executive functions. Less is known regarding the relationship between sleep disturbance and language abilities among individuals with PTSD. We hypothesized that subjective perceptions of PTSD-related sleep disturbance would impact language generativity in Veterans with PTSD. Methods 38 individuals (mean age = 46.58, SD = 13.55; 10% female) were administered a brief neurocognitive battery including measures of verbal generativity [i.e., Delis-Kaplan Executive Function System: Verbal fluency subtest], PTSD symptoms (i.e., clinically significant PTSD = > 35 on the PTSD Checklist for DSM-IV), self-report measures of sleep quality (Pittsburgh Sleep Quality Inventory; PSQI), and PTSD-related sleep disturbances (PSQI – Addendum for PTSD). All participants had a history of mild traumatic brain injury (mTBI). An analysis of covariance was used to assess the contribution of PTSD-related sleep disturbance on verbal fluency in Veterans with PTSD. Post-hoc analyses were conducted. Results Those without PTSD performed better on letter fluency than those with PTSD (p=.019). There was no significant effect of PTSD (presence or absence) on letter fluency performance after controlling for subjective sleep quality, F(1, 35) = 1.43, p = .239. Follow up analyses failed to show any associations between PTSD and other cognitive measures. Conclusions PTSD related sleep disturbance accounts for a significant portion of the variance in the relationship between PTSD and verbal generativity. Individuals with a history of mTBI and current PTSD symptoms, may have worse verbal generativity but is partially accounted for by PTSD related sleep disturbance.


2020 ◽  
Author(s):  
Joseph Carpenter ◽  
Laura Bragdon ◽  
Suzanne L. Pineles

Objective: PTSD is often associated with heightened physiological reactivity during fear conditioning procedures, but results vary across studies. The present study examined whether anxiety sensitivity (AS), or the fear of arousal-related sensations, strengthens the relationship between PTSD symptoms and skin conductance responses (SCR) during fear conditioning and extinction. Because gonadal hormones implicated in fear learning processes fluctuate across the menstrual cycle, the stability of these relationships in women was examined in two distinct menstrual cycle phases. Method: Thirty-two trauma-exposed women with (n=16) and without PTSD (n=16) completed the Clinician-Administered PTSD Scale, Anxiety Sensitivity Inventory, and a fear conditioning and extinction paradigm during the mid-luteal (mLP) and early-follicular (eFP) menstrual cycle phases. Results: In the mLP, stronger SCR to stimuli paired with shock (CS+) during fear acquisition significantly predicted greater PTSD symptoms only when AS was high and after removing an outlier. This appeared driven by effects on Numbing and Hyperarousal symptom clusters. Other hypothesized interactions between AS and CS responses were not significant. However, in the eFP, differential SCR between the CS+ and CS- during extinction predicted significantly greater PTSD symptoms, and there was a trend for this effect being stronger as AS increased. Conclusions: Results offer preliminary evidence that high AS contributes to a stronger relationship between physiological responses during fear acquisition and PTSD symptoms, at least among women in the mLP. Further research investigating the impact of individual differences in traits such as AS on the relationship between conditioned fear responses and PTSD symptoms is warranted.


2017 ◽  
Vol 5 ◽  
pp. 27-32
Author(s):  
D.R. Strasshofer ◽  
M.L. Pacella ◽  
L.A. Irish ◽  
P.A. Palmieri ◽  
D.M. Johnson ◽  
...  

SLEEP ◽  
2019 ◽  
Vol 42 (Supplement_1) ◽  
pp. A369-A369
Author(s):  
Sarah Valentina Diaz ◽  
Xin Yin ◽  
Irene Perez Ibarra ◽  
Carmela Alcántara

2016 ◽  
Vol 90 ◽  
pp. 210-213 ◽  
Author(s):  
Aaron M. Norr ◽  
Brian J. Albanese ◽  
Joseph W. Boffa ◽  
Nicole A. Short ◽  
Norman B. Schmidt

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A64-A65
Author(s):  
S Nagy ◽  
S M Pickett ◽  
M Hedge ◽  
J Mesa ◽  
R Mechal

Abstract Introduction The relationship between anxiety and sleep has been well-established, with many studies demonstrating the relationship between anxiety and reduced REM time, increased sleep latency, and reduced sleep efficiency. Anxiety sensitivity, or the fear of experiencing anxiety-related sensations, has also been associated with increased sleep latency and sleep dysfunction. This delay in sleep onset may be explained by increased arousal, both physical and cognitive, immediately before sleep related to worry or anxiety. The current study examined the relationship between anxiety and subjective sleep quality through pre-sleep arousal and investigated the moderating effect of anxiety sensitivity. Methods Participants (n=322) were recruited from Amazon’s MTurk site, with most identifying as female (58.5%) and White/Caucasian (84.4%) and with an average age of 37.51 (SD = 12.12). Participants completed the Daily Assessment of Symptoms - Anxiety Scale (DAS-A), the Anxiety Sensitivity Index (ASI), the Pre-Sleep Arousal Scale (PSAS) and the Pittsburg Sleep Quality Index (PSQI). A moderated mediation analysis was conducted using Model 58 in PROCESS for SPSS. Results Results indicated that pre-sleep arousal partially mediated the relationship between anxiety and the dichotomous sleep quality variable while controlling for the covariates of age, and therapy participation, (a1= .186, p<.001, b1= .113, p<.001, c’= .038, p<.001). Additionally, the conditional effects and interactions of the moderating anxiety sensitivity variable were significant in both pathways (a1: F=24.702, p<.001; b1: χ 2 = 5.255, p=0.22). Conclusion These results help to identify potential mechanisms and conditions of the relationship between anxiety and sleep quality and contribute to the development of evidence-based interventions for sleep disturbance or other sleep complaints in individuals experiencing anxiety and anxiety symptoms. Support N/A


2016 ◽  
Vol 37 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Nicole L. Hofman ◽  
Austin M. Hahn ◽  
Christine K. Tirabassi ◽  
Raluca M. Gaher

Abstract. Exposure to traumatic events and the associated risk of developing Posttraumatic stress disorder (PTSD) symptoms is a significant and overlooked concern in the college population. It is important for current research to identify potential protective factors associated with the development and maintenance of PTSD symptoms unique to this population. Emotional intelligence and perceived social support are two identified protective factors that influence the association between exposure to traumatic events and PTSD symptomology. The current study examined the mediating role of social support in the relationship between emotional intelligence and PTSD symptoms. Participants included 443 trauma-exposed university students who completed online questionnaires. The results of this study indicated that social support mediates the relationship between emotional intelligence and reported PTSD symptoms. Thus, emotional intelligence is significantly associated with PTSD symptoms and social support may play an integral role in the relationship between emotional intelligence and PTSD. The current study is the first to investigate the role of social support in the relationship between emotional intelligence and PTSD symptoms. These findings have important treatment and prevention implications with regard to PTSD.


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