scholarly journals Sphingosine-1-phosphate receptor: a novel therapeutic target in ulcerative colitis

2016 ◽  
Vol 12 (11) ◽  
pp. 1137-1139 ◽  
Author(s):  
Roberta Izzo ◽  
Michele M. Figliuzzi ◽  
Giovanni Monteleone
Keyword(s):  
Ulcerative Colitis ◽  
Therapeutic Target ◽  
Sphingosine 1 Phosphate ◽  
Novel Therapeutic

Sa1784 The Aryl Hydrocarbon Receptor on Dendritic Cells in Ulcerative Colitis: A Novel Therapeutic Target Linking Diet to Disease Pathogenesis

2013 ◽  
Vol 144 (5) ◽  
pp. S-305
Author(s):  
Elizabeth R. Mann ◽  
Jonathan Landy ◽  
David Bernardo Ordiz ◽  
Hafid O. Al-Hassi ◽  
Simon T. Peake ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Dendritic Cells ◽  
Aryl Hydrocarbon Receptor ◽  
Therapeutic Target ◽  
Disease Pathogenesis ◽  
Aryl Hydrocarbon ◽  
Novel Therapeutic

scholarly journals Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

Blood ◽  
2013 ◽  
Vol 122 (3) ◽  
pp. 443-455 ◽  
Author(s):  
Guoqi Zhang ◽  
Li Yang ◽  
Gab Seok Kim ◽  
Kieran Ryan ◽  
Shulin Lu ◽  
...  
Keyword(s):  
Vascular Permeability ◽  
Therapeutic Target ◽  
Vascular Inflammation ◽  
Critical Role ◽  
Vascular Disorders ◽  
Vascular Integrity ◽  
Key Points ◽  
Sphingosine 1 Phosphate ◽  
Novel Therapeutic

Key Points Endothelial S1PR2 plays a critical role in the induction of vascular permeability and vascular inflammation during endotoxemia. S1PR2 could be a novel therapeutic target to promote vascular integrity in inflammatory vascular disorders.

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