Therapeutic Benefits of Alpha-Lipoic Acid Supplementation in Diabetes Mellitus: A Narrative Review

2021 ◽  
pp. 1-20
Author(s):  
Sarah Jeffrey ◽  
Punitha Isaac Samraj ◽  
Behin Sundara Raj
Keyword(s):  
Diabetes Mellitus ◽  
Lipoic Acid ◽  
Narrative Review ◽  
Alpha Lipoic Acid ◽  
Acid Supplementation ◽  
Therapeutic Benefits

scholarly journals Effect of the Administration of Alpha-Lipoic Acid on Contrast Sensitivity in Patients with Type 1 and Type 2 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Anna Gębka ◽  
Ewelina Serkies-Minuth ◽  
Dorota Raczyńska
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Contrast Sensitivity ◽  
Lipoic Acid ◽  
Control Group ◽  
Alpha Lipoic Acid ◽  
Acid Supplementation ◽  
Frequency Changes

The aim of this study was to estimate the effects of oral supplementation of alpha-lipoic acid (ALA) on contrast sensitivity (CS) in patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). The study included 12 patients with T1DM aged43±12years, 48 patients with T2DM aged59±10years, and 20 control subjects aged33±8years. Patients from each studied group, including the control group, were randomly assigned to receive 300 mg of ALA orally once daily for 3 months. CS was evaluated with the Functional Acuity Contrast Test (FACT, Stereo Optical). In the group of patients with T1DM receiving ALA for 3 months CS remained stable and improved in those with T2DM. Reduction of CS in both T1DM and T2DM patients without alpha-lipoic acid supplementation was observed. In the control group on alpha-lipoic acid supplementation, CS improvement was noticed at one spatial frequency. Changes in the CS were observed, despite stable visual acuity and eye fundus image in all studied subjects. Our study demonstrated that oral administration of alpha-lipoic acid had influence on CS in both T1DM and T2DM patients.

The effect of alpha lipoic acid supplementation on sperm functions in idiopathic asthenozoospermic patients: a case-controlled study

2022 ◽  
pp. 1-9
Author(s):  
Yahya M. Hodeeb ◽  
Emad M. El-Rewiny ◽  
Abdullah M. Gaafar ◽  
Ahmed N. Zayed ◽  
Mohamed S. Hasan ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Controlled Study ◽  
Alpha Lipoic Acid ◽  
Acid Supplementation ◽  
Sperm Functions
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