Acute kidney injury in low- and middle-income countries: investigations, management and prevention

2017 ◽  
Vol 37 (4) ◽  
pp. 269-272 ◽  
Author(s):  
Mohamed B. Abdelraheem
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Acute Kidney Injury: Risk Factors and Management Challenges in Low- and Middle-Income Countries

2020 ◽  
pp. 60-67
Author(s):  
Daniela Ponce ◽  
Nilo Kazan ◽  
Adler Pereira ◽  
Andre Babi
Keyword(s):  
Health Care ◽  
Acute Kidney Injury ◽  
Developing Countries ◽  
Global Health ◽  
Injury Risk ◽  
Kidney Injury ◽  
Middle Income ◽  
Middle Income Countries ◽  
Few Data ◽  
Low And Middle Income

Acute kidney injury (AKI) is a major global health problem, occurring in >13 million people and responsible for >2.3 million deaths every year, 85% of which are in developing countries. Although the International Society of Nephrology (ISN) set a goal of eliminating preventable deaths by AKI by 2025, implementation of this program in developing countries presents major challenges for several reasons: there are few data on the epidemiology and causes of AKI in low- and middle-income countries (LMIC); health care resources to diagnose, manage, and treat AKI are often limited; and governments, institutions, and global health initiatives have not focussed sufficiently on the AKI problems. Thus, developing and implementing effective strategies to eliminate preventable deaths from AKI in LMIC have required efforts to better understand how to increase the awareness of AKI by health care workers and institutions.

scholarly journals Acute Kidney Injury Recognition in Low- and Middle-Income Countries

2017 ◽  
Vol 2 (4) ◽  
pp. 530-543 ◽  
Author(s):  
Jorge Cerdá ◽  
Sumit Mohan ◽  
Guillermo Garcia-Garcia ◽  
Vivekanand Jha ◽  
Srinivas Samavedam ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Predictors of mortality in children with acute kidney injury in intensive care unit

2019 ◽  
Vol 59 (2) ◽  
pp. 92-7
Author(s):  
Umi Rakhmawati ◽  
Indah K. Murni ◽  
Desy Rusmawatiningtyas
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Protective Factor ◽  
Kidney Injury ◽  
Pediatric Intensive Care ◽  
P Value ◽  
Middle Income ◽  
Predictors Of Mortality ◽  
Middle Income Countries

Background Acute kidney injury (AKI) can increase the morbidity and mortality in children admitted to the pediatric intensive care unit (PICU). Previous published studies have mostly been conducted in high-income countries. Evaluations of possible predictors of mortality in children with AKI in low- and middle-income countries have been limited, particularly in Indonesia. Objective To assess possible predictors of mortality in children with AKI in the PICU. Methods We conducted a retrospective cohort study at Dr. Sardjito Hospital, Yogyakarta, Indonesia. All children with AKI admitted to PICU for more than 24 hours from 2010 to 2016 were eligible and consecutively recruited into the study. Logistic regression analysis was used to identify independent predictors. Results Of the 152 children with AKI recruited, 119 died. In order to get a P value of <0.25, multivariate analysis is run to degree AKI, ventilator utilization, primary infection disease, MOF and age.Multivariate analysis showed that ventilator use, severe AKI, and infection were independently associated with mortality in children with AKI, with odds ratios (OR) of 19.2 (95%CI 6.2 to 59.7; P<0.001), 8.6 (95%CI 2.7 to 27.6; P<0.001), and 0.2 (95%CI 0.1 to 0.8; P=0.02), respectively. Conclusion The use of mechanical ventilation and the presence of severe AKI are associated with mortality in children with AKI admitted to the PICU. Interestingly, the presence of infection might be a protective factor from mortality in such patients. 

scholarly journals Acute Kidney Injury in Poor Countries Should No Longer Be a Death Sentence: The ISN ‘0 by 25' Project

2015 ◽  
Vol 66 (Suppl. 3) ◽  
pp. 42-44 ◽  
Author(s):  
Norberto Perico ◽  
Giuseppe Remuzzi
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Death Sentence ◽  
Public And Private ◽  
Middle Income ◽  
Poor Countries ◽  
The Public ◽  
Middle Income Countries ◽  
Timely Fashion

Acute kidney injury (AKI) is a common disorder throughout the world that is associated with severe morbidity, mortality and cost. Although deaths due to AKI occur in both high- and low- and middle-income countries (LMIC), the majority of avoidable deaths occur in LMIC nations. If managed adequately and in a timely fashion, the majority of these cases of AKI are preventable, treatable and often reversible with simple measures. AKI also has a major economic impact on healthcare expenditure. This is particularly true in poor countries where AKI especially impacts young productive people, imposing severe penury on their families. The International Society of Nephrology (ISN) has launched a long-term program, the ‘0 by 25' project, which advocates that zero people should die of untreated AKI in the poorest part of Africa, Asia and Latin America by 2025. The mission is to eventually lessen the high burden in terms of deaths consequent to this disorder in resource-poor regions worldwide. This is a challenging but potentially feasible and productive initiative that requires a broad vision about how the public and private sectors can work in partnership with the governments of the LMIC countries and leading nongovernmental organizations operating locally, to ensure sustainability of the 0 by 25 program and save many lives.

scholarly journals National trends in age-standardized incidence and mortality rates of acute kidney injury in Peru

2020 ◽  
Vol 42 (3) ◽  
pp. 330-337 ◽  
Author(s):  
Percy Herrera-Añazco ◽  
Maycol Suker Ccorahua-Ríos ◽  
Mirian Condori-Huaraka ◽  
Yerika Huamanvilca-Yepez ◽  
Elard Amaya ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Secondary Data ◽  
Mortality Rates ◽  
Epidemiological Studies ◽  
Linear Regression Models ◽  
Middle Income ◽  
Middle Income Countries ◽  
Incidence And Mortality ◽  
National Trends

ABSTRACT Introduction: Acute kidney injury (AKI) is a common disorder that causes high healthcare costs. There are limited epidemiological studies of this disorder in low- and middle-income countries. The aim of this study was to describe trends in the age-standardized incidence and mortality rates of AKI in Peru. Methods: We conducted an ecological study based on a secondary data sources of the basic cause of death from healthcare and death records obtained from establishments of the Ministry of Health of Peru for the period 2005-2016. The age-standardized incidence and mortality rates of AKI were described by region and trend effects were estimated by linear regression models. Results: During the period 2005-2016, 26,633 cases of AKI were reported nationwide. The age-standardized incidence rate of AKI per 100,000 people increased by 15.2%, from 10.5 (period 2005-2010) to 12.1 (period 2011-2016). During the period 2005-2016, 6,812 deaths due to AKI were reported, which represented 0.49% of all deaths reported for that period in Peru. The age-standardized mortality rate of AKI per 100,000 people decreased by 11.1%, from 2.7 (period 2005-2010) to 2.4 (period 2011-2016). The greatest incidence and mortality rates were observed in the age group older than 60 years. Conclusions: During the study period, incidence of AKI increased and mortality decreased, with heterogeneous variations among regions.

Some Conditions for Task Shifting in Low and Middle-Income Countries

2012 ◽  
Author(s):  
Joop de Jong ◽  
Mark Jordans ◽  
Ivan Komproe ◽  
Robert Macy ◽  
Aline & Herman Ndayisaba ◽  
...  
Keyword(s):  
Task Shifting ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income
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