Post-vaccination campaign coverage evaluation of oral cholera vaccine, oral polio vaccine and measles–rubella vaccine among Forcibly Displaced Myanmar Nationals in Bangladesh

ObjectivesTo evaluate the quality and coverage of the campaign to distribute oral cholera vaccine (OCV) during a cholera outbreak in Hoima, Uganda to guide future campaigns of cholera vaccine.DesignSurvey of communities targeted for vaccination to determine vaccine coverage rates and perceptions of the vaccination campaign, and a separate survey of vaccine staff who carried out the campaign.SettingHoima district, Uganda.ParticipantsRepresentative clusters of households residing in the communities targeted for vaccination and staff members who conducted the vaccine campaign.ResultsAmong 209 households (1274 individuals) included in the coverage survey, 1193 (94%; 95% CI 92% to 95%) reported receiving at least one OCV dose and 998 (78%; 95% CI 76% to 81%) reported receiving two doses. Among vaccinated individuals, minor complaints were reported by 71 persons (5.6%). Individuals with ‘some’ education (primary school or above) were more knowledgeable regarding the required OCV doses compared with non-educated (p=0.03). Factors negatively associated with campaign implementation included community sensitisation time, staff payment and problems with field transport. Although the campaign was carried out quickly, the outbreak was over before the campaign started. Most staff involved in the campaign (93%) were knowledgeable about cholera control; however, 29% did not clearly understand how to detect and manage adverse events following immunisation.ConclusionThe campaign achieved high OCV coverage, but the surveys provided insights for improvement. To achieve high vaccine coverage, more effort is needed for community sensitisation, and additional resources for staff transportation and timely payment for campaign staff is required. Pretest and post-test assessment of staff training can identify and address knowledge and skill gaps.

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Social and cultural determinants of anticipated acceptance of an oral cholera vaccine prior to a mass vaccination campaign in Zanzibar

Human Vaccines ◽

10.4161/hv.7.12.18012 ◽

2011 ◽

Vol 7 (12) ◽

pp. 1299-1308 ◽

Cited By ~ 12

Author(s):

Christian Schaetti ◽

Claire-Lise Chaignat ◽

Raymond Hutubessy ◽

Ahmed M. Khatib ◽

Said M. Ali ◽

...

Keyword(s):

Vaccination Campaign ◽

Mass Vaccination ◽

Cholera Vaccine ◽

Mass Vaccination Campaign ◽

Cultural Determinants ◽

Oral Cholera Vaccine

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Alternative observational designs to estimate the effectiveness of one dose of oral cholera vaccine in Lusaka, Zambia

Epidemiology and Infection ◽

10.1017/s095026882000062x ◽

2020 ◽

Vol 148 ◽

Author(s):

E. Ferreras ◽

A. Blake ◽

O. Chewe ◽

J. Mwaba ◽

G. Zulu ◽

...

Keyword(s):

Cohort Study ◽

Vaccination Campaign ◽

Case Control ◽

Cholera Vaccine ◽

Mass Vaccination Campaign ◽

Negative Case ◽

Oral Cholera Vaccine ◽

Matched Case ◽

Polymerase Chain ◽

Study Designs

Abstract We conducted a matched case-control (MCC), test-negative case-control (TNCC) and case-cohort study in 2016 in Lusaka, Zambia, following a mass vaccination campaign. Confirmed cholera cases served as cases in all three study designs. In the TNCC, control-subjects were cases with negative cholera culture and polymerase chain reaction results. Matched controls by age and sex were selected among neighbours of the confirmed cases in the MCC study. For the case-cohort study, we recruited a cohort of randomly selected individuals living in areas considered at-risk of cholera. We recruited 211 suspected cases (66 confirmed cholera cases and 145 non-cholera diarrhoea cases), 1055 matched controls and a cohort of 921. Adjusted vaccine effectiveness of one dose of oral cholera vaccine (OCV) was 88.9% (95% confidence interval (CI) 42.7–97.8) in the MCC study, 80.2% (95% CI: 16.9–95.3) in the TNCC design and 89.4% (95% CI: 64.6–96.9) in the case-cohort study. Three study designs confirmed the short-term effectiveness of single dose OCV. Major healthcare-seeking behaviour bias did not appear to affect our estimates. Most of the protection among vaccinated individuals could be attributed to the direct effect of the vaccine.

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Feasibility of a preventive mass vaccination campaign with two doses of oral cholera vaccine during a humanitarian emergency in South Sudan

Transactions of the Royal Society of Tropical Medicine and Hygiene ◽

10.1093/trstmh/tru153 ◽

2014 ◽

Vol 108 (12) ◽

pp. 810-815 ◽

Cited By ~ 16

Author(s):

M. Ilaria Porta ◽

Annick Lenglet ◽

Silvia de Weerdt ◽

Rosa Crestani ◽

Renate Sinke ◽

...

Keyword(s):

Vaccination Campaign ◽

South Sudan ◽

Mass Vaccination ◽

Cholera Vaccine ◽

Humanitarian Emergency ◽

Mass Vaccination Campaign ◽

Oral Cholera Vaccine

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Feasibility and acceptability of oral cholera vaccine mass vaccination campaign in response to an outbreakand floods in Malawi

Pan African Medical Journal ◽

10.11604/pamj.2016.23.203.8346 ◽

2016 ◽

Vol 23 ◽

Cited By ~ 10

Author(s):

Kelias Phiri Msyamboza ◽

Maurice M’bang’ombe ◽

Hannah Hausi ◽

Alexander Chijuwa ◽

Veronica Nkukumila ◽

...

Keyword(s):

Vaccination Campaign ◽

Mass Vaccination ◽

Cholera Vaccine ◽

Mass Vaccination Campaign ◽

Oral Cholera Vaccine

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Pediatric Immunizations: A Review

Journal of Pharmacy Practice ◽

10.1177/089719008900200104 ◽

1989 ◽

Vol 2 (1) ◽

pp. 21-27

Author(s):

Timothy J. O'Brien

Keyword(s):

Adverse Reactions ◽

Oral Polio Vaccine ◽

Controversial Issues ◽

Cowpox Virus ◽

Childhood Diseases ◽

Rubella Vaccine ◽

Inactivated Polio Vaccine ◽

Polio Vaccine ◽

Immunodeficiency Virus ◽

Method Of Production

Since Edward Jenner discovered that injecting cowpox virus into humans could prevent smallpox, the science of immunology has produced many vaccines that have virtually eradicated some of the worst childhood diseases known to mankind. Along with this great benefit, some vaccines carry with them potentially serious side effects. This review considers the mechanisms of immunology and how these are taken advantage of in vaccine production. The pharmacist is then acquainted with each of the vaccines used in childhood: measles, mumps, rubella (MMR); diphtheria, tetanus toxoids, and pertussis (DTP); oral polio vaccine (OPV); inactivated polio vaccine (IPV); and Hemophilus influenza type b vaccine (HIB). A review of each respective disease entity is considered along with each vaccines's method of production, immunization schedule, and adverse reactions. Some of the more controversial issues of vaccination are considered such as the use of live attenuated vaccines in human immunodeficiency virus (HIV) positive children and the inadvertent use of rubella vaccine in pregnant women. This report capitalizes on the most recent recommendations of the Immunization Practices Advisory Committee in order to provide the pharmacist with the most current information in the field of vaccine immunology today.

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Clustered lot quality assurance sampling: a tool to monitor immunization coverage rapidly during a national yellow fever and polio vaccination campaign in Cameroon, May 2009

Epidemiology and Infection ◽

10.1017/s0950268811000331 ◽

2011 ◽

Vol 140 (1) ◽

pp. 14-26 ◽

Cited By ~ 7

Author(s):

L. PEZZOLI ◽

R. TCHIO ◽

A. D. DZOSSA ◽

S. NDJOMO ◽

A. TAKEU ◽

...

Keyword(s):

Quality Assurance ◽

Yellow Fever ◽

Vaccination Campaign ◽

Immunization Coverage ◽

Vaccination Strategy ◽

Oral Polio Vaccine ◽

Polio Vaccine ◽

Polio Vaccination ◽

Lot Quality Assurance Sampling ◽

Low Coverage

SUMMARYWe used the clustered lot quality assurance sampling (clustered-LQAS) technique to identify districts with low immunization coverage and guide mop-up actions during the last 4 days of a combined oral polio vaccine (OPV) and yellow fever (YF) vaccination campaign conducted in Cameroon in May 2009. We monitored 17 pre-selected districts at risk for low coverage. We designed LQAS plans to reject districts with YF vaccination coverage <90% and with OPV coverage <95%. In each lot the sample size was 50 (five clusters of 10) with decision values of 3 for assessing OPV and 7 for YF coverage. We ‘rejected’ 10 districts for low YF coverage and 14 for low OPV coverage. Hence we recommended a 2-day extension of the campaign. Clustered-LQAS proved to be useful in guiding the campaign vaccination strategy before the completion of the operations.

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Faculty Opinions recommendation of Effectiveness of an oral cholera vaccine in Zanzibar: findings from a mass vaccination campaign and observational cohort study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717958846.793464154 ◽

2012 ◽

Author(s):

Carlos Seas ◽

Jorge Alave

Keyword(s):

Cohort Study ◽

Vaccination Campaign ◽

Observational Cohort Study ◽

Mass Vaccination ◽

Cholera Vaccine ◽

Mass Vaccination Campaign ◽

Oral Cholera Vaccine ◽

Observational Cohort

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Polio Supplementary Immunization Activities During COVID-19 Pandemic: Experience from Penampang District, Sabah, Malaysia

Journal of Primary Care & Community Health ◽

10.1177/21501327211029800 ◽

2021 ◽

Vol 12 ◽

pp. 215013272110298

Author(s):

Sam Froze Jiee ◽

Melvin Ebin Bondi ◽

Muhammad Ezmeer Emiral ◽

Anisah Jantim

Keyword(s):

Community Engagement ◽

Vaccination Campaign ◽

Oral Polio Vaccine ◽

Vaccine Uptake ◽

Successful Implementation ◽

Healthcare Staff ◽

District Health ◽

Polio Vaccine ◽

The Past ◽

Supplementary Immunization Activities

Background: Polio Supplementary Immunization Activities (SIAs) were carried out in the State of Sabah in response to the Vaccine Derived Poliovirus outbreak declared in December 2019. Prior to this, Malaysia had been polio-free over the past 27 years. This paper reported on the successful implementation of SIAs in the district of Penampang, Sabah, adapting (vaccine administration) to the COVID-19 pandemic. Methods: A series of meticulous planning, healthcare staff training, advocacy, and community engagement activities were conducted by the Penampang District Health Office. Bivalent Oral Polio Vaccine (bOPV) and monovalent Oral Polio Vaccine were administered over the period of 1 year via these methods: house to house, drive-through, static, and mobile posts. The targeted group was 22 096 children aged 13 years and below. Results: Polio SIAs in Penampang managed to achieve more than 90% coverage for both bOPV and mOPV. The overall vaccine wastage was reported to be 1.63%. No major adverse reaction was reported. Conclusion: High vaccine uptake during Polio SIAs in Penampang was attributed to good inter-agency collaboration, community engagement, intensified health promotion activities, and drive-through vaccination campaign.

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