Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditions.
1992 ◽
Vol 175
(6)
◽
pp. 1789-1792
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Keyword(s):
The receptors that mediate monocyte adhesion to cytokine-stimulated endothelial monolayers were assessed using a nonstatic (rotating) cell-attachment assay. In this system, leukocyte adhesion molecule-1 (LAM-1) (L-selectin) mediated a major portion (87 +/- 15% at 37 degrees C) of monocyte attachment to activated endothelium. mAb blocking of endothelial leukocyte adhesion molecule-1 (41% inhibition), CD18 (36%), and vascular cell adhesion molecule-1 (25%) function had lesser effects on attachment. These results suggest that LAM-1 may serve an important role in monocyte attachment to endothelium at sites of inflammation.
1992 ◽
Vol 89
(5)
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pp. 1445-1452
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Keyword(s):
1993 ◽
Vol 1
(2)
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pp. 133-142
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2015 ◽
Vol 3
(1)
◽
pp. 22
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1991 ◽
Vol 88
(16)
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pp. 7430-7433
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1992 ◽
Vol 176
(4)
◽
pp. 1183-1189
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1991 ◽
Vol 96
(5)
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pp. 763-770
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2001 ◽
Vol 29
(4)
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pp. 776-781
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