scholarly journals CHEMICAL CHANGES IN THE BLOOD OF THE DOG IN EXPERIMENTAL PERITONITIS

1928 ◽  
Vol 48 (3) ◽  
pp. 339-342 ◽  
Author(s):  
Thomas G. Orr ◽  
Russell L. Haden
Keyword(s):  
Carbon Dioxide ◽  
Intestinal Obstruction ◽  
Cause Of Death ◽  
Protein Nitrogen ◽  
Chemical Changes ◽  
General Peritonitis ◽  
Experimental Peritonitis ◽  
Carbon Dioxide Combining Power ◽  
High Intestinal Obstruction

1. A study of the blood chlorides, urea and non-protein nitrogen and the carbon dioxide-combining power in experimental general peritonitis is here reported. 2. The similarity between the chemical changes in high intestinal obstruction and general peritonitis is noted. These chemical changes suggest that the cause of death may be, at least in part, the same in the two diseases.

scholarly journals CHEMICAL CHANGES IN THE BLOOD OF THE DOG AFTER PYLORIC OBSTRUCTION

1923 ◽  
Vol 37 (3) ◽  
pp. 377-381 ◽  
Author(s):  
Russell L. Haden ◽  
Thomas G. Orr
Keyword(s):  
Intestinal Obstruction ◽  
Protein Metabolism ◽  
Close Relation ◽  
Inorganic Salts ◽  
Pyloric Obstruction ◽  
Marked Rise ◽  
Protein Nitrogen ◽  
Chemical Changes ◽  
Chemical Studies ◽  
High Intestinal Obstruction

Chemical studies of the blood and urine of four dogs following pyloric obstruction are reported. The observations of other workers that a fall in chlorides and a rise in CO2-combining power of the plasma occur, are confirmed. There is also a marked rise in the non-protein nitrogen of the blood, consisting mainly of urea nitrogen and undetermined nitrogen. The fall in chlorides is not due to the loss of chlorides in the gastric juice. The chlorine is probably bound somewhere in the process of protein destruction. There is a close relation between the fall in chlorides and the protein destruction. A study of tetany should include the protein metabolism as well as that of the inorganic salts, since it seems possible that the tetany is due to protein split-products and not to the alkalosis. The chemical changes following pyloric obstruction are essentially the same as those following high intestinal obstruction.

scholarly journals EXPERIMENTAL HIGH INTESTINAL OBSTRUCTION IN THE MONKEY

1925 ◽  
Vol 41 (1) ◽  
pp. 107-111 ◽  
Author(s):  
Russell L. Haden ◽  
Thomas G. Orr
Keyword(s):  
Uric Acid ◽  
Intestinal Obstruction ◽  
Marked Rise ◽  
Protein Nitrogen ◽  
High Intestinal Obstruction ◽  
Marked Drop

The blood findings in five monkeys after experimental high intestinal obstruction are reported. All animals showed the marked rise in non-protein nitrogen characteristic of intestinal obstruction in man and the dog. Two monkeys showed a very marked drop in chlorides, the others a less marked fall. Coincident with the change in chlorides there is a rise in the CO2-combining power. The uric acid and creatinine showed no typical changes. No vomiting was observed. This emphasizes the fact that vomiting alone does not account for the fall in blood chlorides characteristic of intestinal obstruction.

scholarly journals EXPERIMENTAL DEHYDRATION: CHEMICAL CHANGES IN THE BLOOD OF THE DOG CONTRASTED WITH THOSE FOLLOWING OBSTRUCTION OF THE CARDIAC END OF THE STOMACH

1929 ◽  
Vol 49 (6) ◽  
pp. 945-953 ◽  
Author(s):  
Russell L. Haden ◽  
Thomas G. Orr
Keyword(s):  
Body Weight ◽  
Total Protein ◽  
Urine Output ◽  
Average Duration ◽  
Chemical Study ◽  
Protein Nitrogen ◽  
Chemical Changes ◽  
Urea Nitrogen

A comparative chemical study of the blood and the urine of the dog with experimental dehydration and with obstruction of the cardiac end of the stomach is reported. The average duration of life is slightly longer with dehydration than with obstruction. The urine output per kilo of body weight is almost twice as great in dehydration as with obstruction. The increase in non-protein nitrogen and urea nitrogen is much the same in the two groups although somewhat more marked with obstruction. The chlorides of the blood are markedly increased with dehydration and slightly decreased with obstruction. The increase in fibrinogen and total protein is twice as great with obstruction as with dehydration. These findings indicate that there must be some factor or factors in addition to dehydration producing the toxemia of cardiac obstruction.

scholarly journals CHEMICAL STUDIES OF THE BLOOD IN HIGH INTESTINAL OBSTRUCTION

1932 ◽  
Vol 11 (3) ◽  
pp. 475-488 ◽  
Author(s):  
William DeWitt Andrus ◽  
George M. Guest ◽  
Richard F. Gates ◽  
Alta Ashley
Keyword(s):  
Intestinal Obstruction ◽  
Chemical Studies ◽  
High Intestinal Obstruction
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