scholarly journals Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures

2019 ◽  
Vol 1400 ◽  
pp. 033001 ◽  
Author(s):  
D N Osinnikova ◽  
E B Moroshkina ◽  
E S Mokronosova
Keyword(s):  
Nucleic Acids ◽  
Sodium Hypochlorite ◽  
Secondary Structures

scholarly journals Chlorine and its importance in the inactivation of bacteria, can it inactivate viruses?

2021 ◽  
Vol 39 (4) ◽  
Author(s):  
Laila Nayzzel Muñoz-Castellanos ◽  
Alejandra Borrego-Loya ◽  
Cindy Viviana Villalba-Bejarano ◽  
Román González-Escobedo ◽  
Nuvia Orduño-Cruz ◽  
...  
Keyword(s):  
Amino Acids ◽  
Nucleic Acids ◽  
Sodium Hypochlorite ◽  
Active Ingredient ◽  
Hypochlorous Acid ◽  
Cell Damage ◽  
Membrane Components ◽  
Fast Acting ◽  
Sulfur Containing ◽  
Inactivation Of Bacteria

Sodium hypochlorite (NaClO) and its active ingredient, hypochlorous acid (HClO), are the most widely used chlorine-based disinfectants. HClO is a fast-acting antimicrobial that interacts with many biomolecules, including amino acids, lipids, nucleic acids, and sulfur containing membrane components, causing cell damage. In this review, we present examples of the effectiveness of chlorine in general disinfection procedures to inactivate bacteria and, under some conditions, bacteria in biofilms and viruses.

scholarly journals Reaction of Sodium Hypochlorite with Nucleic Acids and Their Constituents

1971 ◽  
Vol 19 (10) ◽  
pp. 2189-2192 ◽  
Author(s):  
HIKOYA HAYATSU ◽  
SHOEKUNG PAN ◽  
TYUNOSIN UKITA
Keyword(s):  
Nucleic Acids ◽  
Sodium Hypochlorite

The Secondary Structures of Nucleic Acids in Organic Solvents1

1961 ◽  
Vol 83 (1) ◽  
pp. 138-142 ◽  
Author(s):  
George K. Helmkamp ◽  
Paul O. P. Ts'o
Keyword(s):  
Nucleic Acids ◽  
Secondary Structures

scholarly journals A short peptide that preferentially binds c-MYC G-quadruplex DNA

2020 ◽  
Vol 56 (63) ◽  
pp. 8940-8943 ◽  
Author(s):  
Aisling Minard ◽  
Danielle Morgan ◽  
Federica Raguseo ◽  
Anna Di Porzio ◽  
Denise Liano ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Human Genome ◽  
Promoter Region ◽  
Secondary Structures ◽  
Quadruplex Dna ◽  
Short Peptide ◽  
G Quadruplex

G-quadruplexes are nucleic-acids secondary structures that are highly abundant in the human genome. In this work,we identified a short-peptide that displays selectivity for the G-quadruplex formed in the promoter region of the oncogene c-MYC.

Molybdenum disulfide@5-carboxyfluorescein-probe biosensor for unamplified specific fragment detection in long nucleic acids based on magnetic composite probe-actuated deblocking of secondary structure

2020 ◽  
Vol 12 (39) ◽  
pp. 4813-4822
Author(s):  
Bin Guo ◽  
Yurong Yan ◽  
Lu Fan ◽  
Haiping Wu ◽  
Min Zhao ◽  
...  
Keyword(s):  
Secondary Structure ◽  
Nucleic Acids ◽  
Molybdenum Disulfide ◽  
Secondary Structures ◽  
Magnetic Composite ◽  
Specific Location ◽  
Specific Fragment ◽  
Location Point

Secondary structures in long circulating tumor nucleic acids have potential obstacles for specific location point hybridized detection of gene fragments.

scholarly journals On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging

2017 ◽  
Vol 53 (59) ◽  
pp. 8249-8260 ◽  
Author(s):  
Özden Karaca ◽  
Samuel M. Meier-Menches ◽  
Angela Casini ◽  
Fritz E. Kühn
Keyword(s):  
Nucleic Acids ◽  
Secondary Structures ◽  
Binding Modes ◽  
Dna Secondary Structures

This perspective review aims at providing an overview of the most representative examples of bioactive metal NHC complexes reacting with nucleic acidsviadifferent binding modes.

Stabilization of hairpins and bulged secondary structures of nucleic acids by single incorporation of α,β-D-CNA featuring a gauche(+) alpha torsional angle

RSC Advances ◽  
2014 ◽  
Vol 4 (90) ◽  
pp. 48821-48826 ◽  
Author(s):  
Béatrice Gerland ◽  
Pierre Millard ◽  
Christelle Dupouy ◽  
Brice-Loïc Renard ◽  
Jean-Marc Escudier
Keyword(s):  
Nucleic Acids ◽  
Secondary Structures ◽  
Torsional Angle ◽  
Dna Hairpin

A constrained dinucleotide unit featuring a gauche(+) alpha torsional angle configuration was used to stabilize DNA hairpin or bulged structures.

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