scholarly journals Small angle X-ray scattering study of poly(N-isopropyl acrylamide) based cryogels near the volume-phase transition temperature

2010 ◽  
Vol 247 ◽  
pp. 012041 ◽  
Author(s):  
Mohand Chalal ◽  
Françoise Ehrburger-Dolle ◽  
Isabelle Morfin ◽  
Maria-Rosa Aguilar de Armas ◽  
Maria-Luisa López ◽  
...  
Keyword(s):  
Phase Transition ◽  
Transition Temperature ◽  
Phase Transition Temperature ◽  
Small Angle ◽  
Volume Phase Transition ◽  
X Ray ◽  
Volume Phase ◽  
X Ray Scattering ◽  
Isopropyl Acrylamide ◽  
Scattering Study

Controlled Release of Growth Factor Using Poly(N-Isopropyl Acrylamide)Copolymer Hydrogels with Different Volume Phase Transition Temperatures

2005 ◽  
Vol 277-279 ◽  
pp. 77-81
Author(s):  
Young A Han ◽  
Jeong Ok Lim ◽  
Jin Hyun Choi ◽  
Byung Chul Ji
Keyword(s):  
Phase Transition ◽  
Transition Temperature ◽  
Phase Transition Temperature ◽  
Crosslinking Agent ◽  
Volume Phase Transition ◽  
Release Behavior ◽  
Volume Phase ◽  
Volume Phase Transition Temperature ◽  
Isopropyl Acrylamide ◽  
Phase Transition Temperatures

The release behavior of the basic fibroblast growth factor (bFGF) from copolymer hydrogels of N-isopropyl acrylamide (NIPAAm) and sodium methacrylate (SMA) was investigated in relation to the volume phase transition temperatures, which was increased by the incorporation of SMA. In the case of the copolymer hydrogels, a higher volume phase transition temperature was obtained when poly(ethylene glycol) diacrylate (PEGDA) was used as the crosslinking agent, suggesting that the chain length of the crosslinking agent has a significant affect on the volume phase transition temperature of a P(NIPAAm-co-SMA) hydrogel. The concentration of bFGF released from the hydrogels with PEGDA increased relative to the water content, thereby showing a dependence on the volume phase transition temperature. Hence, the release behavior of bFGF from the PNIPAAm and P(NIPAAm-co-SMA) hydrogels was found to be affected by the volume phase transition temperature, which can be easily controlled by changing the comonomer, monomer feed ratio, and crosslinking agent.

Necklace-like microstructure in shallow-quenched aqueous solutions of poly(n-isopropylacrylamide), detected by advanced small-angle neutron scattering methods

Soft Matter ◽  
2019 ◽  
Vol 15 (4) ◽  
pp. 671-682 ◽  
Author(s):  
Satoshi Koizumi ◽  
Masahiko Annaka ◽  
Dietmar Schwahn
Keyword(s):  
Phase Transition ◽  
Aqueous Solutions ◽  
Neutron Scattering ◽  
Small Angle ◽  
Small Angle Neutron Scattering ◽  
Volume Phase Transition ◽  
Volume Phase ◽  
Isopropyl Acrylamide

The microstructure of aqueous poly(N-isopropyl acrylamide) (PNIPA) gel and solution was investigated by small-angle neutron scattering (SANS) in the vicinity of the gel volume phase transition at TV (= 34 °C).

A redox-labile poly(oligo(ethylene glycol)methacrylate)-based nanogel with tunable thermosensitivity for drug delivery

2016 ◽  
Vol 7 (10) ◽  
pp. 1913-1921 ◽  
Author(s):  
Yefei Tian ◽  
Shanshan Bian ◽  
Wuli Yang
Keyword(s):  
Phase Transition ◽  
Drug Delivery ◽  
Transition Temperature ◽  
Ethylene Glycol ◽  
Phase Transition Temperature ◽  
Precipitation Polymerization ◽  
Volume Phase Transition ◽  
Glycol Methacrylate ◽  
Volume Phase ◽  
Volume Phase Transition Temperature

We developed a redox degradable P(MEO2MA-s-s-OEGMA) nanogel with tunable volume phase transition temperature for drug delivery via precipitation polymerization using a disulfide-containing crosslinker.

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