Radiopacity endowed magnetic nanocomposite with hyperthermia and in vitro mineralization potential: a combinatorial therapeutic system for osteosarcoma

Author(s):  
Sneha K.R. ◽  
Sreeja S ◽  
Sailaja GS
2015 ◽  
Vol 72 ◽  
pp. 218-226 ◽  
Author(s):  
Federica Boraldi ◽  
Angelica Bartolomeo ◽  
Caterina Di Bari ◽  
Andrea Cocconi ◽  
Daniela Quaglino

2021 ◽  
pp. 2004418
Author(s):  
Bernette Maria Oosterlaken ◽  
Maria Paula Vena ◽  
Gijsbertus With

2006 ◽  
Vol 309-311 ◽  
pp. 493-496 ◽  
Author(s):  
G.S. Sailaja ◽  
T.V. Kumari ◽  
Yoshiyuki Yokogawa ◽  
H.K. Varma

Poly(2-hydroxyethyl methacrylate-co- methyl methacrylate) HM, was synthesized by free radical copolymerization, cross-linked with ethylene glycol dimethacrylate and phosphorylated. The phosphate coupling was ensured by ATR spectroscopy. The in vitro mineralization ability of the phosphorylated HM (designated as PHM) was investigated by studying the nucleation and growth of calcium phosphate on its surface by immersing in simulated body fluid (SBF) solution. The coating morphology was studied by SEM and the Ca/P ratio of the coating by EDX analysis. The cell adhesion behaviour of PHM was studied by seeding Human osteosarcoma (HOS) cells for one week followed by SEM analysis along with HM as control. It was observed that HOS cells exhibited biomineralization of calcium phosphate on the surface of HM as well as on PHM with a significantly higher amount on the surface of PHM as observed by von kossa staining method. The results show that PHM is capable of in vitro mineralization under simulated physiological condition, promotes cell adhesion by providing an excellent cell friendly surface and it exhibits biomineralization of calcium phosphate in presence of HOS cells.


1993 ◽  
Vol 19 (14) ◽  
pp. 1755-1808 ◽  
Author(s):  
Y. Nozaki ◽  
M. Kakumoto ◽  
M. Ohta ◽  
K. Yukimatsu ◽  
Yie W. Chien

2003 ◽  
Vol 240-242 ◽  
pp. 715-718 ◽  
Author(s):  
Motohiro Hirose ◽  
Noriko Kotobuki ◽  
Hiroko Machida ◽  
E. Uchimura ◽  
Hajime Ohgushi

2007 ◽  
Vol 141 (5) ◽  
pp. 729-736 ◽  
Author(s):  
Masahiko Maeda ◽  
Motohiro Hirose ◽  
Hajime Ohgushi ◽  
Tadaaki Kirita

2017 ◽  
Vol 12 (2) ◽  
pp. 02C413 ◽  
Author(s):  
Katarzyna Kępa ◽  
David J. T. Hill ◽  
Lisbeth Grøndahl

2010 ◽  
Vol 33 (7) ◽  
pp. 1025-1033 ◽  
Author(s):  
Mamatha Tirunagari ◽  
Venkateswara Rao Jangala ◽  
Mukkanti Khagga ◽  
Ramesh Gannu

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