Determination of glucose in human urine by cyclic voltammetry method using gold electrode

The anodic behaviour of carbamazepine (CBZ), an anticonvulsant drug, has been studied on gold electrode in 0.1 mol dm-3 phosphate buffer of pH 7.0 by using cyclic voltammetry. It has been found that the value of the oxidative current of pure CBZ at +0.90 V is a linear function of the concentration in a range from 1.0?10-7 to 1.0?10?4 mol dm?3. The detection of CBZ in the concentration of 1.0?10-8 mol dm-3 is among the lowest that have been reported for this drug using voltammetric techniques. CBZ as a content of tablet Galepsine? has been quantitatively determined. It has also been demonstrated that the modification of gold electrode with bovine serum albumin (BSA) results in a decrease of the oxidative peak current due to the binding of the drug to BSA.

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The qualitative determination of oseltamivir phosphate in Tamiflu® capsule by cyclic voltammetry

Hemijska industrija ◽

10.2298/hemind100908070a ◽

2011 ◽

Vol 65 (1) ◽

pp. 87-91 ◽

Cited By ~ 3

Author(s):

Milka Avramov-Ivic ◽

Slobodan Petrovic ◽

Dusan Mijin ◽

Katica Drljevic-Djuric

Keyword(s):

Cyclic Voltammetry ◽

Electrochemical Method ◽

Gold Electrode ◽

Cyclic Voltammogram ◽

Carbon Electrode ◽

Experimental Conditions ◽

Concentration Dependency ◽

Oseltamivir Phosphate ◽

Qualitative Determination

A gold electrode was applied in the voltammetric determination of oseltamivir phosphate standard in 0.05 M NaHCO3. Oseltamivir phosphate as a standard and as a component of Tamiflu? capsule exhibited the identical cyclic voltammogram. The peaks originated from excipients in capsule do not appear under the applied electrochemical conditions. The electrochemical method for the qualitative determination of oseltamivir phosphate in Tamiflu? capsule by cyclic voltammetry was developed. The presence of oseltamivir phosphate as standard and as a content of Tamiflu? capsule in electrolyte as well as their concentrations were simultaneously checked by HPLC. The lack of the current/concentration dependency was established. The not pretreated glassy carbon electrode cannot be used for the determination of oseltamivir phosphate under identical experimental conditions presented for gold electrode.

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Standard Test Method for Determination of the Content of Nitroxide Radical (4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl) in Butadiene, Styrene and Isoprene by Cyclic Voltammetry Method

10.1520/d8301-21 ◽

2021 ◽

Author(s):

Keyword(s):

Cyclic Voltammetry ◽

Nitroxide Radical ◽

Standard Test ◽

Test Method ◽

Standard Test Method ◽

Cyclic Voltammetry Method ◽

Butadiene Styrene

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Standard Test Method for Determination of the Content of Nitroxide Radical (4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl) in Butadiene, Styrene and Isoprene by Cyclic Voltammetry Method

10.1520/d8301 ◽

2021 ◽

Author(s):

Keyword(s):

Cyclic Voltammetry ◽

Nitroxide Radical ◽

Standard Test ◽

Test Method ◽

Standard Test Method ◽

Cyclic Voltammetry Method ◽

Butadiene Styrene

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Electrochemical Detection of Dopamine at a Gold Electrode Modified with a Polypyrrole–Mesoporous Silica Molecular Sieves (MCM-48) Film

International Journal of Molecular Sciences ◽

10.3390/ijms20010111 ◽

2018 ◽

Vol 20 (1) ◽

pp. 111 ◽

Cited By ~ 12

Author(s):

Izabela Zablocka ◽

Monika Wysocka-Zolopa ◽

Krzysztof Winkler

Keyword(s):

Ascorbic Acid ◽

Cyclic Voltammetry ◽

Detection Limit ◽

Modified Electrode ◽

Electrochemical Detection ◽

Molecular Sieves ◽

Gold Electrode ◽

Square Wave Voltammetry ◽

Wave Voltammetry

A gold electrode modified with a polypyrrole–mesoporous silica molecular sieves (polypyrrole—MCM-48) nanostructure film was used for the electrochemical determination of small concentrations of dopamine (DA) by cyclic voltammetry and square-wave voltammetry techniques. This electrode showed good electrocatalytic activity for the oxidation of dopamine. The oxidation potential of dopamine was decreased significantly compared with that obtained at the bare gold electrode. The observed linear range for the determination of the dopamine concentration, without interferents through cyclic voltammetry measurements, was from 10 μM to 1.2 mM (R2 = 0.9989) for the gold electrode modified with the polypyrrole—MCM-48 nanostructure, with a detection limit of 2.5 μM. In the case of square-wave voltammetry, the linear range was 2–250 μM, with a correlation coefficient of 0.9996, and the detection limit was estimated to be 0.7 μM. The effects of interferents, such as ascorbic acid (AA) and uric acid (UA), on the electrochemical detection of dopamine were also examined. The modified electrode can successfully separate the oxidation potentials for ascorbic acid and dopamine, shifting the oxidation peak potential of ascorbic acid to a more positive potential, and significantly decreasing the peak current. The presence of ascorbic acid increased the sensitivity of dopamine determination at the modified electrode, and the detection limit was estimated to be 0.5 μM with 0.1 mM ascorbic acid to imitate physiological solutions. Additionally, studies showed that the presence of uric acid does not affect the electrochemical detection of dopamine. The modified electrode can be successfully applied for the quantitative analysis of dopamine both with and without interferents.

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The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine

Journal of the Serbian Chemical Society ◽

10.2298/jsc121228032n ◽

2013 ◽

Vol 78 (9) ◽

pp. 1373-1385 ◽

Cited By ~ 8

Author(s):

Marina Nevescanin ◽

Milka Avramov-Ivic ◽

Slobodan Petrovic ◽

Dusan Mijin ◽

Sonja Banovic-Stevic ◽

...

Keyword(s):

Quantitative Determination ◽

Human Urine ◽

High Performance ◽

Gold Electrode ◽

Simple Procedure ◽

Reference Method ◽

Linear Increase ◽

Urine Samples ◽

Amphetamine Derivatives

The catalytic abilities of gold electrode were tested for the quantitative determination of amphetamine (A) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) standards by their oxidation using cyclic voltammetry (CV). The value of the oxidative currents of A and MDMA standards at 0.80 V vs. SCE in 0.05 M NaHCO3 at the scan rate of 50 mV/s is linear function of concentration in range of 110.9-258.9 mM and 38.7-229.2 mM, respectively. Square wave voltammetry (SWV) revealed linear increase of current with concentration of MDMA (range 30.9-91.6 mM) and thus quantitative determination of amphetamine derivates. SWV analysis is successfully performed in spiked urine samples as well. A and MDMA in the presence of sucrose and as a content in illegally produced tablets were also analyzed. The voltammetric determination of A and MDMA derivatives using CV and SWV at gold electrode is a rapid, selective and simple procedure and its accuracy was confirmed with reference method, high performance liquid chromatography (HPLC). The spiked urine samples analysis offers additional possibility for the rapid detection of A and MDMA in human urine.

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Electrochemical Preparation and Application of PEDOT/Ferrocene Modified Electrode

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.727-728.61 ◽

2015 ◽

Vol 727-728 ◽

pp. 61-64 ◽

Cited By ~ 1

Author(s):

Xin Fei Zhou ◽

Yan Hui Song ◽

Kun Yun He ◽

Hai Tao Zheng ◽

Shinichiro Suye

Keyword(s):

Ascorbic Acid ◽

Cyclic Voltammetry ◽

Electron Microscope ◽

Electrochemical Impedance Spectroscopy ◽

Modified Electrode ◽

Gold Electrode ◽

Electrochemical Impedance ◽

Electrochemical Preparation ◽

Scanning Electron

A highly stable and sensitive electrochemical sensor was developed by electropolymerisation of poly (3, 4-ethylenedioxythiophene) (PEDOT) and ferrocene (Fc) on gold electrode for the determination of ascorbic acid (AA). The PEDOT/Fc composite film modified Au electrode was characterized by field emission scanning electron microscope，electrochemical impedance spectroscopy and cyclic voltammetry. Compared with bare electrode, the PEDOT/Fc modified electrode exhibited excellent electrocatalytic activity toward the oxidation of AA.

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