SARS-COV-2 infection in people living with HIV: experience from a tertiary hospital in Madrid

2021 ◽  
Author(s):  
Maria Gonzalez Guembe ◽  
Yago Tisner Pensado ◽  
Francisco Tejerina Picado ◽  
Cristina Diez ◽  
Leire Perez Latorre ◽  
...  
Keyword(s):  
Tertiary Hospital ◽  
People Living With Hiv ◽  
Living With Hiv

scholarly journals Human cytomegalovirus infection, viraemia and retinitis among people living with HIV/AIDS in Kano, North-Western Nigeria

2021 ◽  
Vol 9 (8) ◽  
pp. 2191
Author(s):  
Chinagozi P. Edwin ◽  
Sadiq Hassan ◽  
Philips I. Ebisike ◽  
Saudat G. Habib ◽  
Taiwo G. Amole ◽  
...  
Keyword(s):  
Human Cytomegalovirus ◽  
Hcmv Infection ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Cd4 Cells ◽  
Cross Sectional ◽  
Cd4 Cell Count ◽  
Living With Hiv ◽  
Cd4 Cell

Background: Human cytomegalovirus (HCMV) is a leading cause of opportunistic infection in HIV-infected patients. HCMV viraemia is an active infection marker and prelude to end-organ diseases (EODs), such as retinitis. The aim of the study was to assess the burden and associated factors of HCMV infection, viraemia and retinitis among HIV-infected patients in Nigeria.Methods: Comparative cross-sectional study of 160 HIV-infected adults, comprising 80 participants in each of <100/mm3 and ≥100 cells/mm3 CD4+ cell count groups, who attended HIV clinic at a tertiary hospital located in a major Nigerian city.  A questionnaire was used to collect data from eligible consenting participants and their case files. Sera from all participants were tested for anti-HCMV IgG using ELISA method, and plasma of seropositive participants were subjected to PCR for HCMV viraemia. Participants whose samples were HCMV viraemic were examined for HCMV retinitis using indirect ophthalmoscopy. Data was analyzed using Minitab vs 14.1.1PP.Results: All 160 participants tested positive for anti-HCMV IgG. HCMV viraemia was 14.4% (23 of 160) generally, but comparatively more among <100 CD4 cells/mm3 group (18.8%; 15 of 80) than in ≥100 cells/mm3 patient group (10%; 8 of 80). Only HCMV viraemic patients in <100 CD4 cells/mm3 group (20%; 3 of 15) were diagnosed with HCMV retinitis. WHO stage was associated with HCMV viraemia (χ2= 7.79, p=0.05) and HCMV retinitis (χ2= 4.60, p=0.03). The only predictor of HCMV retinitis was WHO staging I and II [aOR = 0.04, 95%CI (0.01- 0.52)].  Conclusions: Evidence of previous and active HCMV infection is prevalent among PLWHA in Nigeria with WHO staging being associated and a predictor of HCMV viraemia and retinitis, respectively.

scholarly journals Low Partner Testing in High HIV Prevalence Setting in Freetown, Sierra Leone: A Retrospective Study

2019 ◽  
Author(s):  
Sulaiman Lakoh ◽  
Emmanuel Firima ◽  
Darlinda F. Jiba ◽  
Momodu Sesay ◽  
Mariama Marco Conteh ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Sierra Leone ◽  
Tertiary Hospital ◽  
Hiv Prevalence ◽  
People Living With Hiv ◽  
Hiv Diagnosis ◽  
Partner Testing ◽  
Hiv Test ◽  
Living With Hiv ◽  
Testing And Counseling

Abstract Objective: Despite a 1.5% national HIV prevalence, 33% of people living with HIV in Sierra Leone know their status. Limited activities on testing partners of HIV patients could be contributory to this substantial unawareness of HIV status. We carried out a retrospective study aimed at assessing partner testing and HIV prevalence among adults (≥15 years) tested using DetermineTM and SD Bioline as recorded in the HIV testing registers from January to December 2017 at Connaught Hospital, an urban tertiary hospital in Sierra Leone. Results: Of the 3808 clients tested for HIV, 2048(53.8%) were females. The median age was 31 (IQR 24 – 42) years and 2104 (55.3%) were single. While 3014(79.1%) had Provider-Initiated Testing and Counseling (PITC), 794 (20.9%) had Client-Initiated Testing and Counseling (CITC). HIV test was positive in 925 (24.3%) {CI 22.9 – 25.6, P< 0.001} clients. Of the 17 (0.4%) partners tested for HIV, 9 (52.9%) were positive. PITC yielded more HIV positive cases (760, 25.2%) than CITC (165, 20.8%). Partner testing (P=0.007), female sex (P<0.001) and PITC (P=0.006) were associated with a positive HIV diagnosis. With high HIV prevalence and low partner testing, activities on partner testing are needed to improve the response to the epidemic.

scholarly journals Low partner testing in high HIV prevalence setting in Freetown, Sierra Leone: a retrospective study

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Sulaiman Lakoh ◽  
Emmanuel Firima ◽  
Darlinda F. Jiba ◽  
Momodu Sesay ◽  
Mariama Marco Conteh ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Sierra Leone ◽  
Tertiary Hospital ◽  
Hiv Prevalence ◽  
People Living With Hiv ◽  
Hiv Diagnosis ◽  
Partner Testing ◽  
Hiv Test ◽  
Living With Hiv ◽  
Testing And Counseling

Abstract Objective Despite a 1.5% National HIV prevalence, less than 40% of people living with HIV in Sierra Leone know their status. Limited activities on testing partners of HIV patients could be contributory to this substantial unawareness of HIV status. We carried out a retrospective study aimed at assessing partner testing and HIV prevalence among adults (≥ 15 years) tested using Determine™ and SD Bioline as recorded in the HIV testing registers from January to December 2017 at Connaught Hospital, an urban tertiary hospital in Sierra Leone. Results Of the 3808 clients tested for HIV, 2048 (53.8%) were females. The median age was 31 (IQR 24–42) years and 2104 (55.3%) were single. While 3014 (79.1%) had Provider-Initiated Testing and Counseling (PITC), 794 (20.9%) had Client-Initiated Testing and Counseling (CITC). HIV test was positive in 925 (24.3%) {CI 22.9–25.6, P < 0.001} clients. Of the 17 (0.4%) partners tested for HIV, 9 (52.9%) were positive. PITC yielded more HIV positive cases (760, 25.2%) than CITC (165, 20.8%). Partner testing (P = 0.007), female sex (P < 0.001) and PITC (P = 0.006) were associated with a positive HIV diagnosis. With high HIV prevalence and low partner testing, activities on partner testing are needed to improve the response to the epidemic.

scholarly journals Self–reported reasons for seeking HIV testing by people living with HIV/AIDS(PLWHA) in a tertiary hospital in Nigeria

2011 ◽  
Vol 1 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Rotimi S Owolabi ◽  
Olusoji Daniel ◽  
Margaret O Araoye ◽  
Gordon K Osagbemi ◽  
Louis Odeigah ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Tertiary Hospital ◽  
People Living With Hiv ◽  
Living With Hiv ◽  
Hiv Aids

scholarly journals Neurological manifestations among patients with HIV – active tuberculosis co infection

2020 ◽  
Author(s):  
Amira Sidig ◽  
Mohamed A. Taha ◽  
Osman.B.M ◽  
Musaab M.Alfaki ◽  
Mohamed I. Alfaki ◽  
...  
Keyword(s):  
Case Series ◽  
Latent Tuberculosis ◽  
Tertiary Hospital ◽  
Active Tuberculosis ◽  
People Living With Hiv ◽  
Neurological Manifestations ◽  
Case Series Study ◽  
Sub Saharan ◽  
Living With Hiv ◽  
Series Study

Abstract Introduction: At least one-third of the 35.3 million people living with HIV worldwide are infected with latent tuberculosis. Tuberculosis is the most common presenting illness among people living with HIV, including those who are taking antiretroviral treatment. There were an estimated 1.1 million HIV positive new TB cases globally in 2012. Around 75% of these people live in sub-Saharan Africa.Despite its great burden, neurological manifestations have not been described yet in patients with HIV-active tuberculosis, although tuberculosis and HIV have synergistic influence on immunity system which may contribute to change in prevalence or severity of CNS involvement in patients with HIV-active TB co infection.Objectives: To study neurological manifestations in patients with HIV-active tuberculosisMethodology: A case series study of 58 consecutive patients with laboratory confirmed HIV- active tuberculosis co infection attending tertiary hospital for tuberculosis treatment was conducted. Data about neurological symptoms and signs – conducted by a neurologist- were collected from each patient. .Results: 24% of 58 patients were found to have neurological manifestations in clinical assessment.Conclusion: the frequency of neurological manifestations among patients with HIV-active TB co infection was found to be higher compared to that of patients with HIV only;

Sign in / Sign up

Export Citation Format

Share Document