The Influence of Nebulized Drugs on Nasal Ciliary Activity

2016 ◽  
Vol 29 (4) ◽  
pp. 378-385 ◽  
Author(s):  
Mieke Boon ◽  
Mark Jorissen ◽  
Martine Jaspers ◽  
Patrick Augustijns ◽  
François L. Vermeulen ◽  
...  
Author(s):  
Anthony Paparo ◽  
Judy A. Murphy ◽  
Robert Dean

In the mid-1950's, fingernail clams virtually disappeared from a 100-mile section of the IL River, a tributary of the Mississippi River, due to unknown causes. A survey of the bottom fauna of the IL River in 1979, revealed that the clams were still absent from the middle reach of the River, where they had been abundant prior to the die-off in the 1950's. Some factor(s) in the River currently prevent the clams from recolonizing areas where they were formerly abundant. Recently, clams exposed to fluoride developed abnormal grooves in the shell matrix. Fluorides are known to be protoplasmic poisons removing essential body calcium by precipitation. Since the shell consists primarily of Ca carbonate, this investigation examines the possible role of fluoride on shell formation and the poisoning of the Ca pump which can directly inhibit lateral ciliary activity on the gill.


Author(s):  
Anthony A. Paparo ◽  
Judith A. Murphy

The purpose of this study was to localize the red neuronal pigment in Mytilus edulis and examine its role in the control of lateral ciliary activity in the gill. The visceral ganglia (Vg) in the central nervous system show an over al red pigmentation. Most red pigments examined in squash preps and cryostat sec tions were localized in the neuronal cell bodies and proximal axon regions. Unstained cryostat sections showed highly localized patches of this pigment scattered throughout the cells in the form of dense granular masses about 5-7 um in diameter, with the individual granules ranging from 0.6-1.3 um in diame ter. Tissue stained with Gomori's method for Fe showed bright blue granular masses of about the same size and structure as previously seen in unstained cryostat sections.Thick section microanalysis (Fig.l) confirmed both the localization and presence of Fe in the nerve cell. These nerve cells of the Vg share with other pigmented photosensitive cells the common cytostructural feature of localization of absorbing molecules in intracellular organelles where they are tightly ordered in fine substructures.


2000 ◽  
Vol 25 (4) ◽  
pp. 331-332
Author(s):  
W.M. Boek ◽  
N. Keles ◽  
K. Graamans ◽  
E.H. Huizing

Toxicology ◽  
1982 ◽  
Vol 23 (1) ◽  
pp. 41-55 ◽  
Author(s):  
Bertil Petersson ◽  
Margareta Curvall ◽  
Curt R. Enzell

Author(s):  
H Eyigor ◽  
E A Cetinkaya ◽  
D T Coban ◽  
G Ozturk ◽  
Ö Erdem

Abstract Objective External dacryocystorhinostomy is thought to cause mucociliary dysfunction by damaging the mucosa, in turn affecting ciliary activity and mucus quality. This study investigated the effect of external dacryocystorhinostomy on sinonasal function. Methods Patients scheduled for unilateral external dacryocystorhinostomy who underwent endoscopic nasal examination and paranasal sinus computed tomography were included in this study. A saccharine test was performed on the planned surgical side and the mucociliary clearance time was determined. The sinonasal quality of life was measured in all patients, pre-operatively and at six months post-operatively, using the Sino-Nasal Outcome Test-22. The Lund–Kennedy endoscopic score was also determined in all patients, both pre- and post-operatively. Results The study comprised 28 patients (22 females and 6 males). A statistically significant difference was found between the pre- and post-operative saccharine test results (p = 0.006), but not between the pre- and post-operative Sino-Nasal Outcome Test-22 scores (p > 0.05). Conclusion This study is one of only a few to investigate the effect of external dacryocystorhinostomy on sinonasal function. The results showed that external dacryocystorhinostomy impairs mucociliary clearance. The surgical procedure is well tolerated and does not significantly change nasal symptom scores.


Respiration ◽  
1990 ◽  
Vol 57 (1) ◽  
pp. 37-39 ◽  
Author(s):  
G. Di Benedetto ◽  
M.T. Lopez-Vidriero ◽  
L. Carratù ◽  
S.W. Clarke
Keyword(s):  

1991 ◽  
Vol 111 (sup486) ◽  
pp. 162-175 ◽  
Author(s):  
Yoshihiro Ohashi ◽  
Yoshiaki Nakai ◽  
Yoshikazu Sugiura ◽  
Yoshiharu Ohno ◽  
Hideki Okamoto

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