scholarly journals Vitamin D Deficiency in Postmenopausal Breast Cancer Survivors

2012 ◽  
Vol 21 (4) ◽  
pp. 456-462 ◽  
Author(s):  
Claire F. Friedman ◽  
Angela DeMichele ◽  
H. Irene Su ◽  
Rui Feng ◽  
Shiv Kapoor ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Deficiency ◽  
Breast Cancer Survivors ◽  
Postmenopausal Breast Cancer

Abstract P2-14-11: Vitamin D Deficiency in Post-Menopausal Breast Cancer Survivors

2010 ◽  
Author(s):  
CF Friedman ◽  
A DeMichele ◽  
HI Su ◽  
R Feng ◽  
S Kapoor ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Deficiency ◽  
Breast Cancer Survivors ◽  
Post Menopausal

Vitamin D Receptor (VDR) Allelic Variants Correlating with Response to Vitamin D3 Supplementation in Breast Cancer Survivors

2021 ◽  
pp. 1-14
Author(s):  
Elham Kazemian ◽  
Sayed Hossein Davoodi ◽  
Mohammad Esmaeil Akbari ◽  
Nariman Moradi ◽  
Safoora Gharibzadeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Receptor ◽  
Vitamin D3 ◽  
Breast Cancer Survivors ◽  
Allelic Variants ◽  
Vitamin D3 Supplementation

Breast cancer survivors and vitamin D: A review

Nutrition ◽  
2010 ◽  
Vol 26 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Stephanie L. Hines ◽  
H. Keels S. Jorn ◽  
Kristine M. Thompson ◽  
Jan M. Larson
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Breast Cancer Survivors

Testing an Intervention for Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors

2003 ◽  
Vol 35 (4) ◽  
pp. 333-338 ◽  
Author(s):  
Nancy L. Waltman ◽  
Janice J. Twiss ◽  
Carol D. Ott ◽  
Gloria Jean Gross ◽  
Ada M. Lindsey ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Postmenopausal Breast Cancer

scholarly journals Effects of Vaginal Estrogens on Serum Estradiol Levels in Postmenopausal Breast Cancer Survivors and Women at Risk of Breast Cancer Taking an Aromatase Inhibitor or a Selective Estrogen Receptor Modulator

2012 ◽  
Vol 8 (3) ◽  
pp. 144-148 ◽  
Author(s):  
Shannon Wills ◽  
Anita Ravipati ◽  
Padmaja Venuturumilli ◽  
Cynthia Kresge ◽  
Elizabeth Folkerd ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Survivors ◽  
Aromatase Inhibitor ◽  
Breast Cancer Survivors ◽  
Postmenopausal Breast Cancer ◽  
Serum Estradiol ◽  
Estradiol Treatment ◽  
Receptor Modulator ◽  
Estradiol Levels

The authors conclude that intravaginal estradiol treatment, regardless of type, results in elevated circulating E2 levels in this population and should be used with caution.

scholarly journals Vitamin D Receptor Genetic Variation and Cancer Biomarkers among Breast Cancer Patients Supplemented with Vitamin D3: A Single-Arm Non-Randomized Before and After Trial

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1264 ◽  
Author(s):  
Elham Kazemian ◽  
Mohammad Esmaeil Akbari ◽  
Nariman Moradi ◽  
Safoora Gharibzadeh ◽  
Alison M. Mondul ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Receptor ◽  
Adhesion Molecule ◽  
Vitamin D3 ◽  
Breast Cancer Survivors ◽  
Cancer Biomarkers ◽  
Vitamin D3 Supplementation ◽  
Vdr Polymorphisms

We investigated whether vitamin D receptor (VDR) polymorphisms were associated with cancer biomarkers, i.e., E-cadherin, matrix metallopeptidase 9 (MMP9), interferon β (IFNβ), soluble intercellular adhesion molecule-1 (s-ICAM-1), soluble vascular cell adhesion molecule-1 (s-VCAM-1), tumor necrosis factorα (TNFα), interleukin 6 (IL6), plasminogen activator inhibitor-1(PAI-1), and human high sensitivity C-reactive protein (hs-CRP), among breast cancer survivors who received vitamin D3 supplementation. In a single-arm non-randomized pre- and post trial, 176 breast cancer survivors who had completed treatment protocol including surgery, radio and chemotherapy were enrolled in the study and received 4000 IU of vitamin D3 daily for 12 weeks. The association between the VDR SNPs (ApaI, TaqI, FokI, BsmI and Cdx2) and response variable changes was assessed using linear regression, utilizing the “association” function in the R package “SNPassoc”. We observed that women with AA and GA [codominant model (AA compared to GG) and (GA compared to GG); dominant model (AA & GA compared to GG)] genotypes of Cdx2 showed higher increase in plasma MMP9 levels compared to the GG category. In addition, carriers of BsmI bb showed greater decrease in circulating TNFα levels after vitamin D3 supplementation [recessive model (bb compared to BB & Bb]. Likewise, significant associations were identified between haplotypes of VDR polymorphisms and on-study plasma MMP9 changes. However, our results indicate that VDR genetic polymorphisms were not associated with longitudinal changes in the remaining cancer biomarkers. Overall, our findings suggest that changes in certain inflammatory biomarkers in breast cancer survivors with low plasma 25(OH)D levels, supplemented with vitamin D3, may depend on VDR SNPs and haplotypes.

Sign in / Sign up

Export Citation Format

Share Document