Lean-body-mass composition and resting energy expenditure before and after long-term overfeeding

1992 ◽  
Vol 56 (5) ◽  
pp. 840-847 ◽  
Author(s):  
O Dériaz ◽  
G Fournier ◽  
A Tremblay ◽  
J-P Després ◽  
C Bouchard
Keyword(s):  
Energy Expenditure ◽  
Lean Body Mass ◽  
Body Mass ◽  
Resting Energy Expenditure ◽  
Mass Composition ◽  
Before And After ◽  
Body Mass Composition ◽  
Resting Energy

scholarly journals No consistent evidence of a disproportionately low resting energy expenditure in long-term successful weight-loss maintainers

2018 ◽  
Vol 108 (4) ◽  
pp. 658-666 ◽  
Author(s):  
Danielle M Ostendorf ◽  
Edward L Melanson ◽  
Ann E Caldwell ◽  
Seth A Creasy ◽  
Zhaoxing Pan ◽  
...  
Keyword(s):  
Weight Loss ◽  
Energy Expenditure ◽  
Body Mass ◽  
Resting Energy Expenditure ◽  
Weight Loss Maintenance ◽  
Fat Free Mass ◽  
Predictive Equations ◽  
Successful Weight Loss ◽  
Resting Energy

Abstract Background Evidence in humans is equivocal in regards to whether resting energy expenditure (REE) decreases to a greater extent than predicted for the loss of body mass with weight loss, and whether this disproportionate decrease in REE persists with weight-loss maintenance. Objectives We aimed to1) determine if a lower-than-predicted REE is present in a sample of successful weight-loss maintainers (WLMs) and 2) determine if amount of weight loss or duration of weight-loss maintenance are correlated with a lower-than-predicted REE in WLMs. Design Participants (18–65 y old) were recruited in 3 groups: WLMs (maintaining ≥13.6 kg weight loss for ≥1 y, n = 34), normal-weight controls [NCs, body mass index (BMI; in kg/m2) similar to current BMI of WLMs, n = 35], and controls with overweight/obesity (OCs, BMI similar to pre–weight-loss maximum BMI of WLMs, n = 33). REE was measured (REEm) with indirect calorimetry. Predicted REE (REEp) was determined via 1) a best-fit linear regression developed with the use of REEm, age, sex, fat-free mass, and fat mass from our control groups and 2) three standard predictive equations. Results REEm in WLMs was accurately predicted by equations developed from NCs and OCs (±1%) and by 3 standard predictive equations (±3%). In WLMs, individual differences between REEm and REEp ranged from −257 to +163 kcal/d. A lower REEm compared with REEp was correlated with amount of weight lost (r = 0.36, P < 0.05) but was not correlated with duration of weight-loss maintenance (r = 0.04, P = 0.81). Conclusions We found no consistent evidence of a significantly lower REE than predicted in a sample of long-term WLMs based on predictive equations developed from NCs and OCs as well as 3 standard predictive equations. Results suggest that sustained weight loss may not always result in a substantial, disproportionately low REE. This trial was registered at clinicaltrials.gov as NCT03422380.

Regional lean body mass and resting energy expenditure in non-obese adults

2001 ◽  
Vol 40 (3) ◽  
pp. 93-97 ◽  
Author(s):  
Manfred J. Müller ◽  
Kirsten Illner ◽  
Anja Bosy-Westphal ◽  
Gisbert Brinkmann ◽  
Martin Heller
Keyword(s):  
Energy Expenditure ◽  
Lean Body Mass ◽  
Body Mass ◽  
Resting Energy Expenditure ◽  
Obese Adults ◽  
Resting Energy

Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction

1997 ◽  
Vol 272 (5) ◽  
pp. E901-E907 ◽  
Author(s):  
J. J. Ramsey ◽  
E. B. Roecker ◽  
R. Weindruch ◽  
J. W. Kemnitz
Keyword(s):  
Energy Expenditure ◽  
Lean Body Mass ◽  
Body Mass ◽  
Dietary Restriction ◽  
Adult Male ◽  
Rhesus Monkeys ◽  
Resting Energy Expenditure ◽  
Treatment Groups ◽  
Male Rhesus

Energy expenditure, activity, and body composition were measured in 30 adult male rhesus monkeys used in a study having the long-term goal of determining the effects of moderate dietary restriction (DR) on aging. All animals were fed a defined diet, with the restricted animals maintained at approximately 70% of the caloric intakes of the controls. After 12 mo of DR, body fat mass of restricted monkeys was 33% less than that of controls (P = 0.004), whereas lean body mass differences were not present until after 24 mo. At the 24- and 30-mo assessments, nighttime energy expenditure was significantly reduced (P < 0.01) in the restricted compared with control monkeys after adjustment for lean body mass differences, whereas morning, afternoon, and total energy expenditure were not significantly different (P > 0.05). No significant differences (P > 0.05) in activity were noticed between treatment groups at any time point. DR resulted in a prolonged decrease in resting energy expenditure, which could contribute to the possible life-extending action of this treatment.

Role of cytokines and testosterone in regulating lean body mass and resting energy expenditure in HIV-infected men

2002 ◽  
Vol 283 (1) ◽  
pp. E138-E145 ◽  
Author(s):  
Ronenn Roubenoff ◽  
Steven Grinspoon ◽  
Paul R. Skolnik ◽  
Eric Tchetgen ◽  
Leslie Abad ◽  
...  
Keyword(s):  
Weight Loss ◽  
Energy Expenditure ◽  
Lean Body Mass ◽  
Body Mass ◽  
Highly Active Antiretroviral Therapy ◽  
Mononuclear Cells ◽  
Resting Energy Expenditure ◽  
Gradual Process ◽  
Tnf Α ◽  
Resting Energy

Although catastrophic weight loss is no longer common in HIV-infected men, we hypothesized that a more gradual process of cachexia [loss of lean body mass (LBM) without severe weight loss, often accompanied by elevated resting energy expenditure (REE)] is still common and is driven by excessive production of the catabolic cytokines tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). We performed a longitudinal analysis of an ongoing cohort study of nutritional status in 172 men with HIV infection. LBM loss of >1 kg occurred in 35% of the cohort, and LBM loss of >5% occurred in 12.2% over 8 mo of observation, but classical wasting (loss of ≈10% of weight) was rare (2%). Both TNF-α (−150 g LBM · ng−1· ml−1, P < 0.02) and IL-1β production (−130 g LBM · ng−1· ml−1, P < 0.01) by peripheral blood mononuclear cells predicted loss of LBM. A rise in REE of >200 kcal/day was found in 17.7% of the subjects regardless of weight change. IL-1β (+9 kcal/day per ng/ml, P < 0.002) and TNF-α (+10 kcal/day per ng/ml, P < 0.02) production predicted ΔREE. Serum free testosterone was inversely associated with TNF-α production and was not an independent predictor of either ΔLBM or ΔREE after adjustment for cytokine production. Even though weight loss was rare in this cohort of patients treated with highly active antiretroviral therapy, loss of LBM was common and was driven by catabolic cytokines and not by inadequate dietary intake or hypogonadism.

Sign in / Sign up

Export Citation Format

Share Document