scholarly journals Ossifying Fibroma; A Case report and review of literature

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S83-S84
Author(s):  
S Luceno ◽  
A Lazim ◽  
R Kuklani ◽  
N Jhala
Keyword(s):  
Case Report ◽  
Microscopic Examination ◽  
Accurate Diagnosis ◽  
Growth Potential ◽  
Ossifying Fibroma ◽  
Fibrous Stroma ◽  
Osseous Dysplasia ◽  
Microscopic Evaluation ◽  
Neoplastic Process

Abstract Introduction/Objective Ossifying fibroma (OF) is a rare, benign, true neoplasm with growth potential, with the mandible involved more often than the maxilla. There is female predilection in the third and fourth decades of life, with the most common site being the premolar and molar area of the mandible. These lesions are characterized by the replacement of endogenous bone with a highly cellular fibrous neoplasm containing varied amounts of bony trabeculae, and/or cementum-like spherules. Radiographically they present as well defined, unilocular, most are mixed lucent, opaque, some with sclerotic border and root divergence may be seen. Histologically most of the lesions are not encapsulated but are well demarcated from the adjacent bone. Thus radiographic, surgical and histological findings help distinguish OF from other benign fibro-osseous lesions such as fibrous dysplasia and cemento-osseous dysplasia. Distinguishing an accurate diagnosis between the above fibro-osseous neoplasms becomes significant as prognosis and treatment differ. Methods/Case Report Herein we report a case of a 59-year-old female who presented with a symptomatic mandibular lesion that radiographically illustrated a midline well-circumscribed expansile mass of the mandibular symphysis with a sclerotic margin and ground-glass internal matrix measuring 3.1 x 4.9 x 3.9 cm, favored to represent pagetoid changes more likely than neoplastic process. Microscopic examination revealed numerous variably sized islands of ossification within a hypercellular fibrous stroma. Based on the clinical, radiographic and histologic findings, a diagnosis of benign fibro-osseous lesion, favor ossifying fibroma was given. Results (if a Case Study enter NA) NA Conclusion Microscopic examination, as in our case, can resemble a variety of benign fibro-osseous neoplasms. Radiographic and clinical correlation, along with microscopic evaluation, help solidify the accurate diagnosis.

scholarly journals Peripheral Giant Cell Granuloma: A Case Report with Review on Its Histogenesis and Recurrence

2019 ◽  
Vol 07 (02) ◽  
pp. 095-098
Author(s):  
Deepti Garg Jindal ◽  
Sandhya Singh Kushwaha ◽  
Sonia Joshi ◽  
Namita Sepolia ◽  
Varun Jindal ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Giant Cell ◽  
Growth Potential ◽  
Biological Behavior ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Cell Hyperplasia ◽  
High Tendency ◽  
Peripheral Giant Cell Granuloma

AbstractGiant cell granulomas (GCGs) of the jaws are non-neoplastic lesions that arise either peripherally in periodontal ligament, mucoperiosteum, or centrally in the bone. Histologically, both peripheral and central giant cell granuloma are characterized by the presence of numerous multinucleated giant cells in a prominent fibrous stroma. Peripheral giant cell granuloma is an infrequent reactive, exophytic lesion of the oral cavity, also known as giant-cell epulis, osteoclastoma, giant cell reparative granuloma, or giant cell hyperplasia. It is the most common giant cell lesion of the jaws and originates from the connective tissue of the periosteum or from the periodontal membrane, in response to local irritation or chronic trauma. The lesion develops mostly in adults, commonly in the lower jaw, with slight female predilection although is uncommon in children. Clinically, it shows resemblance to pyogenic granuloma, peripheral ossifying fibroma, and many other peripheral lesions seen in the oral cavity, but in our case it resembled a squamous cell carcinoma, thereby histopathology is mandatory for the diagnosis of this lesion. The lesion although being relatively common, still has a lot of ambiguity. The ambiguity is in terms of its etiology, growth potential, biological behavior (recurrence), histogenesis of its cells, and its treatment. The entity further holds significance because of its notorious behavior and high tendency to recur. This is a case report of a 30-year-old female patient with history of swelling in the lower anterior region of jaw since 1 year. After complete excision of lesion, lesion reoccurred after few months.

Gonococcal arthritis case report

1989 ◽  
Vol 79 (4) ◽  
pp. 190-194 ◽  
Author(s):  
E Hirsch ◽  
M Sherman ◽  
MD Lenet
Keyword(s):  
Case Report ◽  
Clinical Presentation ◽  
Accurate Diagnosis ◽  
Definitive Evidence ◽  
Complete History ◽  
Timely Treatment

In the case reported, the diagnosis of gonococcal arthritis unfolded over the course of 1 week and was not fully conclusive until presumptive therapy was initiated. Although the clinical, microbiologic, and immunologic characteristics of gonococcal arthritis can be differentiated from other types of bacterial arthritides, not all textbook symptoms are present at one time in one particular case. There also are subtle signs that are involved. In this case study, there was little definitive evidence that stood out to confirm the diagnosis. It was the interdependence of a complete history, serologic and radiographic studies, clinical presentation, and demographic considerations that led to an accurate diagnosis and timely treatment of gonococcal arthritis.

scholarly journals Endoscopic Findings and Histopathological Correlation of Esophageal Lesions

2021 ◽  
pp. 1-10
Author(s):  
E. Harish Kumar ◽  
B. O. Parijatham ◽  
Vindu Srivastava
Keyword(s):  
Diagnostic Tool ◽  
Microscopic Examination ◽  
Endoscopic Biopsy ◽  
Accurate Diagnosis ◽  
P53 Expression ◽  
Endoscopic Findings ◽  
Histopathological Correlation ◽  
Microscopic Evaluation ◽  
Esophageal Carcinomas

Incidence of neoplastic and non-neoplastic esophageal lesions. The present study aimed to evaluate the site of occurrence of esophageal carcinomas and to study the various types of esophagitis with histochemical stains. A total of 104 esophageal lesions were received by endoscopic biopsy. A thorough Microscopic evaluation was done in each case. This proves that microscopic examination is the confirmatory diagnostic tool. The microscopic examination along with the accessory histochemical stain, immunohistochemistry for HSV antigen, p53 expression helped to arrive at an accurate diagnosis.

A case of osteofibroma on the symphysis mandible in a cow

2018 ◽  
Vol 69 (1) ◽  
pp. 879
Author(s):  
S YAYLA ◽  
E KILIÇ ◽  
H ÖZEN ◽  
S DAĞ ◽  
V BARAN ◽  
...  
Keyword(s):  
Case Report ◽  
Microscopic Examination ◽  
Histopathological Examination ◽  
Case Reports ◽  
Ossifying Fibroma ◽  
Tumor Mass ◽  
Soccer Ball ◽  
Young Horses

Osteofibroma or ossifying fibroma both in human and animals is a rarely seen benign neoplasia. It usually locates on the mandible. Although it is commonly seen in young horses no case reports were described in cattle. In this case report, an osteofibroma located at the symphysis mandible in a cow was described. The tumor mass was reported to grow over in a two-month period to the size of soccer ball. The mass was totally extirpated and histopathological examination was performed. The mass was diagnosed as osteofibroma in microscopic examination.

scholarly journals Recurrent juvenile psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of the maxilla: a case report and review of literature

2018 ◽  
Author(s):  
Sachin C. Sarode ◽  
Gargi S. Sarode ◽  
Yashwant Ingale ◽  
Manjusha Ingale ◽  
Barnali Majumdar ◽  
...  
Keyword(s):  
Case Report ◽  
Aneurysmal Bone Cyst ◽  
English Literature ◽  
Bone Cyst ◽  
Growth Potential ◽  
Ossifying Fibroma ◽  
Surgical Removal ◽  
Juvenile Ossifying Fibroma ◽  
Secondary Aneurysmal Bone Cyst ◽  
Psammomatoid Ossifying Fibroma

Juvenile ossifying fibroma is a benign fibro-osseous lesion commonly affecting the extra-gnathic craniofacial skeleton of the young individuals. The psammomatoid and trabecular variants are its two histopathological subtypes having distinctive clinico-pathological characteristics. Secondary aneurysmal bone cysts are frequently reported to arise in the pre-existing fibro-osseous lesions but rarely reported in the psammmomatoid variant of the juvenile ossifying fibroma. Such hybrid lesions, especially massive in size, tend to exhibit a greater aggressive growth potential and higher recurrence rate and mandate complete surgical removal of the lesion along with a long-term follow-up. The objective of this case report was to present a rare incident of recurrent psammomatoid ossifying fibroma associated with a secondary aneurysmal bone cyst in the maxillary jaw bone of a young patient and review the similar published reports in the English literature.

scholarly journals Trabecular Juvenile Ossifying Fibroma of the Craniofacial Skeleton: Etiopathogenesis and a Case Report of the Rare Entity

2014 ◽  
Vol 4 (1) ◽  
pp. 51-55
Author(s):  
Shwetha Kumar ◽  
Rahul Kadam
Keyword(s):  
Case Report ◽  
Age Of Onset ◽  
Bone Architecture ◽  
Ossifying Fibroma ◽  
Rare Entity ◽  
Craniofacial Skeleton ◽  
High Tendency ◽  
Fibrous Stroma ◽  
Juvenile Ossifying Fibroma ◽  
Hrpt2 Gene

ABSTRACT The term, fibro-osseous lesions, is used for a group of pathological disturbances encompassing developmental, reactive or dysplastic lesions and neoplasms characterized by replacement of normal bone architecture by tissue composed of collagen fibers and fibroblasts containing various amount of calcified tissue. The groups of the fibro-osseous lesions are best considered as a spectrum of processes arising from cells in the periodontal ligament. Juvenile ossifying fibroma (JOF) is a benign, but potentially aggressive, fibro-osseous tumor of the craniofacial bones. This uncommon neoplasm is distinguished from other fibro-osseous lesions primarily by its age of onset, clinical presentation, potential behavior and the high tendency to recur. Clinically presenting as an actively growing lesion. Histopathologically consists cell rich fibrous stroma containing bands of cellular osteoid without osteoblastic lining together with trabeculae of more typical woven bone. Pathogenesis of JOF may be related to mutations of HRPT2 gene which may arises due to haploinsufficiency of the HRPT2 gene. Here, we reported a case of trabecular JOF (TJOF) which had variations in clinical, radiographic features and histopathological characteristics and it's etiopathogenesis in detail. How to cite this article Kadam R, Patel S, Pathak J, Swain N, Kumar S. Trabecular Juvenile Ossifying Fibroma of the Craniofacial Skeleton: Etiopathogenesis and a Case Report of the Rare Entity. J Contemp Dent 2014;4(1):51-55.

scholarly journals Peripheral Ossifying Fibroma: A Case Report

2020 ◽  
Vol 4 (1) ◽  
pp. 39-42
Author(s):  
Barun Kumar Sah ◽  
Bandana Koirala ◽  
Mamta Dali ◽  
Sneha Shrestha
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Periodontal Ligament ◽  
Ossifying Fibroma ◽  
Reactive Process ◽  
Peripheral Ossifying Fibroma ◽  
Neoplastic Process ◽  
One Year

Peripheral ossifying fibroma (POF) is a common solitary gingival growth thought to arise from the periodontal ligament. Though the etiology of POF remains unknown, some investigators consider it an inflammatory or reactive process, while others suggest it is a neoplastic process. Here, we present a case of POF in a 10-year-old boy, affecting the maxillary anterior gingiva along with its clinical, radiographic, histologic characteristics, differential diagnosis, treatment and one year follow-up.

Misophonia: An Evidence-Based Case Report

2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Case History ◽  
Pure Tone ◽  
Physiological Responses ◽  
Evidence Based ◽  
Management Option ◽  
Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

Intensive Stuttering Therapy With Telepractice Follow-up: A Case Study

2011 ◽  
Vol 21 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Farzan Irani ◽  
Rodney Gabel
Keyword(s):  
Case Report ◽  
Therapeutic Intervention ◽  
Intensive Therapy ◽  
Positive Outcome ◽  
Eclectic Approach

This case report describes the positive outcome of a therapeutic intervention that integrated an intensive, residential component with follow-up telepractice for a 21 year old male who stutters. This therapy utilized an eclectic approach to intensive therapy in conjunction with a 12-month follow-up via video telepractice. The results indicated that the client benefited from the program as demonstrated by a reduction in percent stuttered syllables, a reduction in stuttering severity, and a change in attitudes and feelings related to stuttering and speaking.

Premalignant and Malignant Lesions of the Heterotopic Pancreas in the Esophagus: a Case Report and Review of the Literature

2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Unusual Case ◽  
Accurate Diagnosis ◽  
Heterotopic Pancreas ◽  
Premalignant Lesions ◽  
Resected Specimen ◽  
Review Of The Literature ◽  
Severe Dysphagia ◽  
Malignant Lesions

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.

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