scholarly journals Relationship Between Resting Heart Rate and Carotid–Femoral Pulse Wave Velocity in the Elderly With Prehypertension

2020 ◽  
Vol 33 (12) ◽  
pp. 1146-1146
Author(s):  
Ling-yu Zhang ◽  
Li Luo ◽  
Yi-hua Shen ◽  
Guo-yan Xu ◽  
Liang-di Xie

Abstract Background To investigate the relationship between resting heart rate and carotid–femoral pulse wave velocity (cfPWV) in patients with prehypertension. Methods A total of 288 outpatients with prehypertension and 326 normotensive outpatients from the First Affiliated Hospital of Fujian Medical University were enrolled between March 2017 and March 2019. Body weight, resting heart rate, and blood pressure of all patients were recorded. Blood biochemical indexes and cfPWV were determined. Results Compared with the normotensive controls, cfPWV in the prehypertension group was significantly higher (P < 0.01). There was an increase in cfPWV with advancing age in both prehypertension and control groups, and cfPWV in males was higher than females. In the prehypertension group, after stratified with age and gender, partial correlation analysis showed that resting heart rate was positively correlated with cfPWV (r = 0.230, P < 0.01). After adjusted for other cardiovascular risk factors, multivariable stepwise regression analysis indicated that resting heart rate, age, and gender were independently associated with cfPWV in the prehypertension group (all P < 0.01). Moreover, resting heart rate was independently associated with cfPWV in the patients with prehypertension aged ≥60 years in both males and females (all P < 0.01). However, in patients with prehypertension aged <60 years, no significant correlation was observed between resting heart rate and cfPWV. Conclusions In the elderly with prehypertension, resting heart rate is independently associated with cfPWV.

Author(s):  
Ciro A. Ruiz-Feria ◽  
Yimu Yang ◽  
Donald B. Thomason ◽  
Jarred White ◽  
Guibin Su ◽  
...  

2003 ◽  
Vol 166 (2) ◽  
pp. 303-309 ◽  
Author(s):  
Hirofumi Tomiyama ◽  
Akira Yamashina ◽  
Tomio Arai ◽  
Kenichi Hirose ◽  
Yutaka Koji ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e107852 ◽  
Author(s):  
Anxin Wang ◽  
Jie Tao ◽  
Xiuhua Guo ◽  
Xuemei Liu ◽  
Yanxia Luo ◽  
...  

2021 ◽  
Vol 34 (8) ◽  
pp. 888-888
Author(s):  
Ling-yu Zhang ◽  
Jian-hua Li ◽  
Yi-hua Shen ◽  
Guo-yan Xu ◽  
Ying Han ◽  
...  

Abstract Background To investigate the difference of carotid structural abnormality and stiffness, and the relationship between carotid structural abnormality and stiffness in prehypertensive and normotensive subjects. Methods A total of 581 participants (270 with prehypertension, 311 normotensive control subjects) from the First Affiliated Hospital of Fujian Medical University were enrolled from January 2017 to March 2019. Body height/weight, resting heart rate, and blood pressure were recorded. Blood biochemical indexes and carotid–femoral pulse wave velocity were determined, and carotid ultrasonography was performed. Carotid intima–media thickness ≥1.0 mm and carotid–femoral pulse wave velocity ≥10.0 m/s were defined as carotid structural abnormality and arterial stiffness, respectively. Results The percentage of patients with carotid structural abnormality (60.7% vs. 51.4%), carotid–femoral pulse wave velocity [(8.78 ± 1.48) vs. (7.92 ± 1.30) m/s], and the percentage of patients with arterial stiffness (13.7% vs. 5.8%) were increased in the prehypertension group compared with the control group (all P < 0.05). In the prehypertension group, the percentage of patients with arterial stiffness in the abnormal carotid structure subgroup (n = 164) was higher than that in the normal carotid structure subgroup (n = 106) (20.1% vs. 3.8%, χ2 = 14.551, P < 0.001). Furthermore, carotid structural abnormality, age, diabetes mellitus, resting heart rate, systolic blood pressure, fasting blood glucose, glycosylated hemoglobin A1c, and hypoglycemic therapy were all correlated with arterial stiffness (all P < 0.05). After adjusting for other cardiovascular risk factors, multiple logistic regression analysis showed that carotid structural abnormality, age, diabetes mellitus, and resting heart rate were independently correlated with arterial stiffness, and patients with carotid structural abnormality had 5.25-fold higher risk of arterial stiffness than those with a normal carotid arterial structure (odds ratio = 5.250, 95% confidence interval 1.580–17.448, P = 0.007). However, in the normotensive group, no such relationships were observed between carotid artery structural abnormality and stiffness. Conclusions In prehypertensives but not normotensives, carotid artery structural abnormalities and stiffness are common, and independently correlated.


2012 ◽  
Vol 113 (5) ◽  
pp. 727-735 ◽  
Author(s):  
Alessandra Borlotti ◽  
Ashraf W. Khir ◽  
Ernst R. Rietzschel ◽  
Marc L. De Buyzere ◽  
Sebastian Vermeersch ◽  
...  

We recently introduced noninvasive methods to assess local pulse wave velocity (PWV) and wave intensity (ndI) in arteries based on measurements of flow velocity (U) and diameter (D). Although the methods were validated in an experimental setting, clinical application remains lacking. The aim of this study was therefore to investigate the effect of age and gender on PWV and ndI in the carotid and femoral arteries of an existing population. We measured D and U in the carotid and femoral arteries of 1,774 healthy subjects aged 35-55 yr, a subgroup of the Asklepios population. With the use of the lnDU-loop method, we calculated local PWV, which was used to determine arterial distensibility (nDs). We then used the new algorithm to determine maximum forward and backward wave intensities (ndI+max and ndI−min, respectively) and the reflection index (nRI). On average, PWV was higher, and nDs was lower in the femoral than at the carotid arteries. At the carotid artery, PWV increased with age, but nDs, ndI+max, and ndI−min decreased; nRI did not change with age. At the femoral artery, PWV was higher, and nDs was lower in male, but all parameters did not change significantly with age in both women and men. We conclude that the carotid artery is more affected by the aging process than the femoral artery, even in healthy subjects. The new techniques provide mechanical and hemodynamic parameters, requiring only D and U measurements, both of which can be acquired using ultrasound equipment widely available today, hence their advantage for potential use in the clinical setting.


AGE ◽  
2013 ◽  
Vol 35 (6) ◽  
pp. 2345-2355 ◽  
Author(s):  
Pedro Magalhães ◽  
Daniel P. Capingana ◽  
Amílcar B. T. Silva ◽  
Albano V. L. Ferreira ◽  
Roberto de Sá Cunha ◽  
...  

Angiology ◽  
2017 ◽  
Vol 69 (1) ◽  
pp. 59-64
Author(s):  
Dragan Lovic ◽  
Manolis S. Kallistratos ◽  
Leonidas Poulimenos ◽  
Aggelos Skyrlas ◽  
V. Stojanov ◽  
...  

We compared pulse wave velocity (PWV) between hypertensive patients and control patients to identify demographics and patient characteristics related to PWV. We retrospectively analyzed 9923 participants (3105 controls and 6818 hypertensive patients) from 5 outpatient hypertensive clinics (in Serbia and Greece). Pulse wave velocity had different distribution between controls and hypertensive patients ( P < .001). The magnitude of PWV increase was related to blood pressure (BP) category (from optimal to stage III hypertension; P < .001). Even in hypertensive patients with systolic BP (SBP) <140 and/or diastolic BP (DBP) <90 mm Hg, PWV was greater than in control patients ( P < .001). Pulse wave velocity was associated with almost all baseline characteristics of hypertensive patients (body mass index [BMI], gender, age, SBP, DBP, smoking status, and heart rate; P < .001). This association remained after adjustment of PWV confounders. There were 2231 (32.7%) hypertensive patients who had reached SBP <140 mm Hg and DBP <90 mm Hg. Pulse wave velocity was increased in hypertensive patients, and the degree of PWV increase was associated with baseline BP as well as with anthropometric parameters (eg, BMI, gender, age, heart rate, and smoking status).


Sign in / Sign up

Export Citation Format

Share Document